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Identification
HMDB Protein ID HMDBP13011
Secondary Accession Numbers None
Name Pyridoxal 5'-phosphate synthase subunit PdxS
Synonyms
  1. PLP synthase subunit PdxS
  2. Pdx1
Gene Name PDXS
Protein Type Unknown
Biological Properties
General Function Not Available
Specific Function Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
Pathways
  • Biosynthesis of cofactors
  • pyridoxal 5'-phosphate biosynthesis
  • Vitamin B6 metabolism
Reactions Not Available
GO Classification
Biological Process
pyridoxal phosphate biosynthetic process
Molecular Function
pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity
Cellular Location Not Available
Gene Properties
Chromosome Location Not Available
Locus Not Available
SNPs Not Available
Gene Sequence Not Available
Protein Properties
Number of Residues 295
Molecular Weight 31915.47
Theoretical pI 5.361
Pfam Domain Function
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence Not Available
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID Q4L3H8
UniProtKB/Swiss-Prot Entry Name PDXS_STAHJ
PDB IDs Not Available
GenBank Gene ID Not Available
GeneCard ID Not Available
GenAtlas ID Not Available
HGNC ID Not Available
References
General References
  1. Takeuchi F, Watanabe S, Baba T, Yuzawa H, Ito T, Morimoto Y, Kuroda M, Cui L, Takahashi M, Ankai A, Baba S, Fukui S, Lee JC, Hiramatsu K: Whole-genome sequencing of staphylococcus haemolyticus uncovers the extreme plasticity of its genome and the evolution of human-colonizing staphylococcal species. J Bacteriol. 2005 Nov;187(21):7292-308. doi: 10.1128/JB.187.21.7292-7308.2005. [PubMed:16237012 ]