Identification |
HMDB Protein ID
| HMDBP13143 |
Secondary Accession Numbers
| None |
Name
| 1-deoxy-D-xylulose-5-phosphate synthase |
Synonyms
|
- 1-deoxyxylulose-5-phosphate synthase
- DXP synthase
- DXPS
|
Gene Name
| DXS |
Protein Type
| Unknown |
Biological Properties |
General Function
| Not Available |
Specific Function
| Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP). |
Pathways
|
- 1-deoxy-D-xylulose 5-phosphate biosynthesis
- Biosynthesis of secondary metabolites
- Terpenoid backbone biosynthesis
- Thiamine metabolism
|
Reactions
| Not Available |
GO Classification
|
Biological Process |
thiamine biosynthetic process |
1-deoxy-D-xylulose 5-phosphate biosynthetic process |
terpenoid biosynthetic process |
Molecular Function |
magnesium ion binding |
1-deoxy-D-xylulose-5-phosphate synthase activity |
thiamine pyrophosphate binding |
|
Cellular Location
|
Not Available
|
Gene Properties |
Chromosome Location
| Not Available |
Locus
| Not Available |
SNPs
| Not Available |
Gene Sequence
|
Not Available
|
Protein Properties |
Number of Residues
| 640 |
Molecular Weight
| 69659.575 |
Theoretical pI
| 7.722 |
Pfam Domain Function
|
|
Signals
|
Not Available
|
Transmembrane Regions
|
Not Available
|
Protein Sequence
|
Not Available
|
External Links |
GenBank ID Protein
| Not Available |
UniProtKB/Swiss-Prot ID
| Q6G0D4 |
UniProtKB/Swiss-Prot Entry Name
| DXS_BARQU |
PDB IDs
|
Not Available |
GenBank Gene ID
| Not Available |
GeneCard ID
| Not Available |
GenAtlas ID
| Not Available |
HGNC ID
| Not Available |
References |
General References
| - Alsmark CM, Frank AC, Karlberg EO, Legault BA, Ardell DH, Canback B, Eriksson AS, Naslund AK, Handley SA, Huvet M, La Scola B, Holmberg M, Andersson SG: The louse-borne human pathogen Bartonella quintana is a genomic derivative of the zoonotic agent Bartonella henselae. Proc Natl Acad Sci U S A. 2004 Jun 29;101(26):9716-21. doi: 10.1073/pnas.0305659101. Epub 2004 Jun 21. [PubMed:15210978 ]
|