| Identification |
|---|
| HMDB Protein ID
| HMDBP13144 |
| Secondary Accession Numbers
| None |
| Name
| 1-deoxy-D-xylulose-5-phosphate synthase |
| Synonyms
|
- 1-deoxyxylulose-5-phosphate synthase
- DXP synthase
- DXPS
|
| Gene Name
| DXS |
| Protein Type
| Unknown |
| Biological Properties |
|---|
| General Function
| Not Available |
| Specific Function
| Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP). |
| Pathways
|
- 1-deoxy-D-xylulose 5-phosphate biosynthesis
- Biosynthesis of secondary metabolites
- Terpenoid backbone biosynthesis
- Thiamine metabolism
|
| Reactions
| Not Available |
| GO Classification
|
| Biological Process |
| thiamine biosynthetic process |
| 1-deoxy-D-xylulose 5-phosphate biosynthetic process |
| terpenoid biosynthetic process |
| Molecular Function |
| magnesium ion binding |
| 1-deoxy-D-xylulose-5-phosphate synthase activity |
| thiamine pyrophosphate binding |
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| Not Available |
| Gene Sequence
|
Not Available
|
| Protein Properties |
|---|
| Number of Residues
| 621 |
| Molecular Weight
| 68940.81 |
| Theoretical pI
| 7.44 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
Not Available
|
| External Links |
|---|
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| Q18B68 |
| UniProtKB/Swiss-Prot Entry Name
| DXS_CLOD6 |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| Not Available |
| GeneCard ID
| Not Available |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| - Sebaihia M, Wren BW, Mullany P, Fairweather NF, Minton N, Stabler R, Thomson NR, Roberts AP, Cerdeno-Tarraga AM, Wang H, Holden MT, Wright A, Churcher C, Quail MA, Baker S, Bason N, Brooks K, Chillingworth T, Cronin A, Davis P, Dowd L, Fraser A, Feltwell T, Hance Z, Holroyd S, Jagels K, Moule S, Mungall K, Price C, Rabbinowitsch E, Sharp S, Simmonds M, Stevens K, Unwin L, Whithead S, Dupuy B, Dougan G, Barrell B, Parkhill J: The multidrug-resistant human pathogen Clostridium difficile has a highly mobile, mosaic genome. Nat Genet. 2006 Jul;38(7):779-86. Epub 2006 Jun 25. [PubMed:16804543 ]
|
