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Identification
HMDB Protein ID HMDBP13161
Secondary Accession Numbers None
Name 1-deoxy-D-xylulose-5-phosphate synthase
Synonyms
  1. 1-deoxyxylulose-5-phosphate synthase
  2. DXP synthase
  3. DXPS
Gene Name DXS
Protein Type Unknown
Biological Properties
General Function Not Available
Specific Function Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
Pathways
  • 1-deoxy-D-xylulose 5-phosphate biosynthesis
  • Biosynthesis of secondary metabolites
  • Terpenoid backbone biosynthesis
  • Thiamine metabolism
Reactions Not Available
GO Classification
Biological Process
thiamine biosynthetic process
1-deoxy-D-xylulose 5-phosphate biosynthetic process
terpenoid biosynthetic process
Molecular Function
magnesium ion binding
1-deoxy-D-xylulose-5-phosphate synthase activity
thiamine pyrophosphate binding
Cellular Location Not Available
Gene Properties
Chromosome Location Not Available
Locus Not Available
SNPs Not Available
Gene Sequence Not Available
Protein Properties
Number of Residues 627
Molecular Weight 66781.31
Theoretical pI 5.963
Pfam Domain Function
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence Not Available
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID Q6A8V3
UniProtKB/Swiss-Prot Entry Name DXS_CUTAK
PDB IDs Not Available
GenBank Gene ID Not Available
GeneCard ID Not Available
GenAtlas ID Not Available
HGNC ID Not Available
References
General References
  1. Bruggemann H, Henne A, Hoster F, Liesegang H, Wiezer A, Strittmatter A, Hujer S, Durre P, Gottschalk G: The complete genome sequence of Propionibacterium acnes, a commensal of human skin. Science. 2004 Jul 30;305(5684):671-3. doi: 10.1126/science.1100330. [PubMed:15286373 ]