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| Identification |
|---|
| HMDB Protein ID
| HMDBP13189 |
| Secondary Accession Numbers
| None |
| Name
| 1-deoxy-D-xylulose-5-phosphate synthase |
| Synonyms
|
- 1-deoxyxylulose-5-phosphate synthase
- DXP synthase
- DXPS
|
| Gene Name
| DXS |
| Protein Type
| Unknown |
| Biological Properties |
|---|
| General Function
| Not Available |
| Specific Function
| Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP). |
| Pathways
|
- 1-deoxy-D-xylulose 5-phosphate biosynthesis
- Biosynthesis of secondary metabolites
- Terpenoid backbone biosynthesis
- Thiamine metabolism
|
| Reactions
| Not Available |
| GO Classification
|
| Biological Process |
| isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway |
| thiamine biosynthetic process |
| 1-deoxy-D-xylulose 5-phosphate biosynthetic process |
| terpenoid biosynthetic process |
| Cellular Component |
| cytosol |
| Molecular Function |
| magnesium ion binding |
| 1-deoxy-D-xylulose-5-phosphate synthase activity |
| transferase activity, transferring aldehyde or ketonic groups |
| thiamine pyrophosphate binding |
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| Not Available |
| Gene Sequence
|
Not Available
|
| Protein Properties |
|---|
| Number of Residues
| 647 |
| Molecular Weight
| 71644.49 |
| Theoretical pI
| 7.084 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
Not Available
|
| External Links |
|---|
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| Q8A0C2 |
| UniProtKB/Swiss-Prot Entry Name
| DXS_BACTN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| Not Available |
| GeneCard ID
| Not Available |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| - Xu J, Bjursell MK, Himrod J, Deng S, Carmichael LK, Chiang HC, Hooper LV, Gordon JI: A genomic view of the human-Bacteroides thetaiotaomicron symbiosis. Science. 2003 Mar 28;299(5615):2074-6. doi: 10.1126/science.1080029. [PubMed:12663928 ]
|
