Hmdb loader
Identification
HMDB Protein ID HMDBP13255
Secondary Accession Numbers None
Name Alpha-enolase
Synonyms
  1. 2-phospho-D-glycerate hydro-lyase
  2. Enolase 1
  3. Non-neural enolase
  4. NNE
Gene Name ENO1
Protein Type Unknown
Biological Properties
General Function Not Available
Specific Function Glycolytic enzyme the catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate. In addition to glycolysis, involved in various processes such as growth control, hypoxia tolerance and allergic responses. May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons. Stimulates immunoglobulin production.
Pathways
  • Biosynthesis of amino acids
  • Carbon metabolism
  • glycolysis
  • Glycolysis / Gluconeogenesis
  • HIF-1 signaling pathway
  • RNA degradation
Reactions Not Available
GO Classification
Biological Process
cellular response to interleukin-7
glycolysis
in utero embryonic development
canonical glycolysis
regulation of vacuole fusion, non-autophagic
positive regulation of binding
Cellular Component
cytosol
cell surface
membrane raft
growth cone
cytoplasm
phosphopyruvate hydratase complex
plasma membrane
synaptic membrane
myelin sheath
cell cortex region
membrane
neuron projection
extrinsic component of plasma membrane
Molecular Function
magnesium ion binding
phosphopyruvate hydratase activity
protein-containing complex binding
DNA-binding transcription repressor activity, RNA polymerase II-specific
RNA polymerase II transcription regulatory region sequence-specific DNA binding
heat shock protein binding
RNA binding
protein homodimerization activity
enzyme binding
GTPase binding
identical protein binding
Cellular Location Not Available
Gene Properties
Chromosome Location Not Available
Locus Not Available
SNPs Not Available
Gene Sequence Not Available
Protein Properties
Number of Residues 434
Molecular Weight 47140.415
Theoretical pI 6.803
Pfam Domain Function
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence Not Available
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID P17182
UniProtKB/Swiss-Prot Entry Name ENOA_MOUSE
PDB IDs Not Available
GenBank Gene ID Not Available
GeneCard ID Not Available
GenAtlas ID Not Available
HGNC ID Not Available
References
General References
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