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| Identification |
|---|
| HMDB Protein ID
| HMDBP13323 |
| Secondary Accession Numbers
| None |
| Name
| Lectin |
| Synonyms
|
Not Available
|
| Gene Name
| Not Available |
| Protein Type
| Unknown |
| Biological Properties |
|---|
| General Function
| Not Available |
| Specific Function
| Has metal-independent hemagglutinating activity against erythrocytes from human, sheep, goat, rat, rabbit and chicken. Hemagglutinating activity is inhibited by glycoproteins fetuin, asialo-fetuin, fibrinogen, asialo-fibrinogen, thyroglobulin, bovine (BSM) as well as porcine submaxillary mucin and asialo-BSM but not by sugars alpha-L-fucose, D-glucose, D-galactose, D-glucosamine, D-galactosamine, lactose, D-melibiose, D/L-mannose, D-mannosamine, D-raffinose, L-rhamnose, xylose, glacaturonic acid or N-acetylglucosamine. Has antifungal activity against F.oxysporum (MIC=20 ug/ml), P.chrysogenum (MIC=35 ug/ml), A.niger (MIC=50 ug/ml), C.musae (MIC=60 ug/ml), B.cinerea (MIC=65 ug/ml), T.rubrum (MIC=65 ug/ml), T.tonsurans (MIC=20 ug/ml), T.interdigitale (MIC=20 ug/ml), E.floccosum (MIC=15 ug/ml) and M.canis (MIC=70 ug/ml). |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
| Biological Process |
| killing of cells of other organism |
| positive regulation of erythrocyte aggregation |
| defense response to fungus |
| Molecular Function |
| carbohydrate binding |
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| Not Available |
| Gene Sequence
|
Not Available
|
| Protein Properties |
|---|
| Number of Residues
| Not Available |
| Molecular Weight
| 903.045 |
| Theoretical pI
| Not Available |
| Pfam Domain Function
|
Not Available |
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
Not Available
|
| External Links |
|---|
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| P86922 |
| UniProtKB/Swiss-Prot Entry Name
| LECT_GANLU |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| Not Available |
| GeneCard ID
| Not Available |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| - U Girjal V, Neelagund S, Krishnappa M: Ganoderma lucidum: a source for novel bioactive lectin. Protein Pept Lett. 2011 Nov;18(11):1150-7. doi: 10.2174/092986611797200986. [PubMed:21728991 ]
|
