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Identification
HMDB Protein ID HMDBP13359
Secondary Accession Numbers None
Name 3-ketodihydrosphingosine reductase TSC10
Synonyms
  1. 3-dehydrosphinganine reductase
  2. KDS reductase
Gene Name TSC10
Protein Type Unknown
Biological Properties
General Function Not Available
Specific Function Catalyzes the reduction of 3-ketodihydrosphingosine (KDS) to dihydrosphingosine (DHS).
Pathways
  • sphingolipid metabolism
Reactions Not Available
GO Classification
Biological Process
3-keto-sphinganine metabolic process
sphingolipid biosynthetic process
Cellular Component
endoplasmic reticulum membrane
integral to membrane
Molecular Function
3-dehydrosphinganine reductase activity
Cellular Location Not Available
Gene Properties
Chromosome Location Not Available
Locus Not Available
SNPs Not Available
Gene Sequence Not Available
Protein Properties
Number of Residues 335
Molecular Weight 36489.7
Theoretical pI 8.591
Pfam Domain Function
Signals Not Available
Transmembrane Regions
  • 288-308;
Protein Sequence Not Available
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID P0CR36
UniProtKB/Swiss-Prot Entry Name TSC10_CRYNJ
PDB IDs Not Available
GenBank Gene ID Not Available
GeneCard ID Not Available
GenAtlas ID Not Available
HGNC ID Not Available
References
General References
  1. Loftus BJ, Fung E, Roncaglia P, Rowley D, Amedeo P, Bruno D, Vamathevan J, Miranda M, Anderson IJ, Fraser JA, Allen JE, Bosdet IE, Brent MR, Chiu R, Doering TL, Donlin MJ, D'Souza CA, Fox DS, Grinberg V, Fu J, Fukushima M, Haas BJ, Huang JC, Janbon G, Jones SJ, Koo HL, Krzywinski MI, Kwon-Chung JK, Lengeler KB, Maiti R, Marra MA, Marra RE, Mathewson CA, Mitchell TG, Pertea M, Riggs FR, Salzberg SL, Schein JE, Shvartsbeyn A, Shin H, Shumway M, Specht CA, Suh BB, Tenney A, Utterback TR, Wickes BL, Wortman JR, Wye NH, Kronstad JW, Lodge JK, Heitman J, Davis RW, Fraser CM, Hyman RW: The genome of the basidiomycetous yeast and human pathogen Cryptococcus neoformans. Science. 2005 Feb 25;307(5713):1321-4. doi: 10.1126/science.1103773. Epub 2005 Jan 13. [PubMed:15653466 ]