Identification |
HMDB Protein ID
| HMDBP13373 |
Secondary Accession Numbers
| None |
Name
| Apyrase |
Synonyms
|
- ATP-diphosphatase
- ATP-diphosphohydrolase
- Adenosine diphosphatase
- ADPase
|
Gene Name
| Not Available |
Protein Type
| Unknown |
Biological Properties |
General Function
| Not Available |
Specific Function
| Facilitates hematophagy by inhibiting ADP-dependent platelet aggregation in the host. May reduce probing time by facilitating the speed of locating blood. Platelet aggregation was inhibited by 6% when 0.4 uM recombinant apyrase was added and by 9.5% when the concentration of recombinant apyrase was 0.8 uM. |
Pathways
|
Not Available
|
Reactions
| Not Available |
GO Classification
|
Biological Process |
nucleotide catabolic process |
Cellular Component |
extracellular region |
Molecular Function |
metal ion binding |
8-oxo-dGTP phosphohydrolase activity |
dATP phosphohydrolase activity |
dCTP phosphohydrolase activity |
dGTP phosphohydrolase activity |
dTTP phosphohydrolase activity |
dUTP phosphohydrolase activity |
GTP phosphohydrolase activity |
ATP binding |
hydrolase activity, acting on ester bonds |
|
Cellular Location
|
Not Available
|
Gene Properties |
Chromosome Location
| Not Available |
Locus
| Not Available |
SNPs
| Not Available |
Gene Sequence
|
Not Available
|
Protein Properties |
Number of Residues
| Not Available |
Molecular Weight
| 62750.425 |
Theoretical pI
| Not Available |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
Not Available
|
Protein Sequence
|
Not Available
|
External Links |
GenBank ID Protein
| Not Available |
UniProtKB/Swiss-Prot ID
| E0D877 |
UniProtKB/Swiss-Prot Entry Name
| APY_AEDAL |
PDB IDs
|
Not Available |
GenBank Gene ID
| Not Available |
GeneCard ID
| Not Available |
GenAtlas ID
| Not Available |
HGNC ID
| Not Available |
References |
General References
| - Dong F, Fu Y, Li X, Jiang J, Sun J, Cheng X: Cloning, expression, and characterization of salivary apyrase from Aedes albopictus. Parasitol Res. 2012 Feb;110(2):931-7. doi: 10.1007/s00436-011-2579-x. Epub 2011 Aug 14. [PubMed:21842387 ]
- Arca B, Lombardo F, Francischetti IM, Pham VM, Mestres-Simon M, Andersen JF, Ribeiro JM: An insight into the sialome of the adult female mosquito Aedes albopictus. Insect Biochem Mol Biol. 2007 Feb;37(2):107-27. doi: 10.1016/j.ibmb.2006.10.007. Epub 2006 Nov 7. [PubMed:17244540 ]
|