Identification |
HMDB Protein ID
| HMDBP13390 |
Secondary Accession Numbers
| None |
Name
| Chymotrypsin-like elastase family member 1 |
Synonyms
|
- Elastase-1
|
Gene Name
| CELA1 |
Protein Type
| Unknown |
Biological Properties |
General Function
| Not Available |
Specific Function
| Acts upon elastin. |
Pathways
|
Not Available
|
Reactions
| Not Available |
GO Classification
|
Biological Process |
proteolysis |
Cellular Component |
extracellular space |
Molecular Function |
metal ion binding |
serine-type endopeptidase activity |
|
Cellular Location
|
Not Available
|
Gene Properties |
Chromosome Location
| Not Available |
Locus
| Not Available |
SNPs
| Not Available |
Gene Sequence
|
Not Available
|
Protein Properties |
Number of Residues
| 266 |
Molecular Weight
| 28821.345 |
Theoretical pI
| 8.129 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
Not Available
|
Protein Sequence
|
Not Available
|
External Links |
GenBank ID Protein
| Not Available |
UniProtKB/Swiss-Prot ID
| P00772 |
UniProtKB/Swiss-Prot Entry Name
| CELA1_PIG |
PDB IDs
|
|
GenBank Gene ID
| Not Available |
GeneCard ID
| Not Available |
GenAtlas ID
| Not Available |
HGNC ID
| Not Available |
References |
General References
| - Talas U, Dunlop J, Khalaf S, Leigh IM, Kelsell DP: Human elastase 1: evidence for expression in the skin and the identification of a frequent frameshift polymorphism. J Invest Dermatol. 2000 Jan;114(1):165-70. [PubMed:10620133 ]
- Shirasu Y, Yoshida H, Mikayama T, Matsuki S, Tanaka J, Ikenaga H: Isolation and expression in Escherichia coli of a cDNA clone encoding porcine pancreatic elastase. J Biochem. 1986 Jun;99(6):1707-12. doi: 10.1093/oxfordjournals.jbchem.a135646. [PubMed:3528137 ]
- Tani T, Kawashima I, Furukawa H, Ohmine T, Takiguchi Y: Characterization of a silent gene for human pancreatic elastase I: structure of the 5'-flanking region. J Biochem. 1987 Mar;101(3):591-9. doi: 10.1093/jb/101.3.591. [PubMed:3648024 ]
- Shotton DM, Hartley BS: Evidence for the amino acid sequence of porcine pancreatic elastase. Biochem J. 1973 Apr;131(4):643-75. doi: 10.1042/bj1310643. [PubMed:4578945 ]
- Shotton DM, Hartley BS: Amino-acid sequence of porcine pancreatic elastase and its homologies with other serine proteinases. Nature. 1970 Feb 28;225(5235):802-6. doi: 10.1038/225802a0. [PubMed:5415108 ]
- Sawyer L, Shotton DM, Campbell JW, Wendell PL, Muirhead H, Watson HC: The atomic structure of crystalline porcine pancreatic elastase at 2.5 A resolution: comparisons with the structure of alpha-chymotrypsin. J Mol Biol. 1978 Jan 15;118(2):137-208. doi: 10.1016/0022-2836(78)90412-6. [PubMed:628010 ]
- Shotton DM, Watson HC: Three-dimensional structure of tosyl-elastase. Nature. 1970 Feb 28;225(5235):811-6. doi: 10.1038/225811a0. [PubMed:5415110 ]
- Huang K, Strynadka NC, Bernard VD, Peanasky RJ, James MN: The molecular structure of the complex of Ascaris chymotrypsin/elastase inhibitor with porcine elastase. Structure. 1994 Jul 15;2(7):679-89. doi: 10.1016/s0969-2126(00)00068-x. [PubMed:7922044 ]
|