Hmdb loader
Identification
HMDB Protein ID HMDBP13405
Secondary Accession Numbers None
Name Chymotrypsin-like elastase family member 2A
Synonyms
  1. Elastase-2A
Gene Name CELA2A
Protein Type Unknown
Biological Properties
General Function Not Available
Specific Function Elastase that enhances insulin signaling and might have a physiologic role in cellular glucose metabolism. Circulates in plasma and reduces platelet hyperactivation, triggers both insulin secretion and degradation, and increases insulin sensitivity.
Pathways
  • Pancreatic secretion
  • Protein digestion and absorption
Reactions Not Available
GO Classification
Biological Process
insulin catabolic process
response to insulin stimulus
regulation of platelet aggregation
cornification
proteolysis
regulation of insulin secretion
Cellular Component
cytosol
keratohyalin granule
extracellular region
extracellular space
Molecular Function
endopeptidase activity
serine hydrolase activity
serine-type endopeptidase activity
Cellular Location Not Available
Gene Properties
Chromosome Location Not Available
Locus Not Available
SNPs Not Available
Gene Sequence Not Available
Protein Properties
Number of Residues 269
Molecular Weight 28887.5
Theoretical pI 8.459
Pfam Domain Function
Signals
  • 1-16;
Transmembrane Regions Not Available
Protein Sequence Not Available
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID P08217
UniProtKB/Swiss-Prot Entry Name CEL2A_HUMAN
PDB IDs Not Available
GenBank Gene ID Not Available
GeneCard ID Not Available
GenAtlas ID Not Available
HGNC ID Not Available
References
General References
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