Hmdb loader
Identification
HMDB Protein ID HMDBP13440
Secondary Accession Numbers None
Name Phosphoribosylformylglycinamidine cyclo-ligase
Synonyms
  1. AIR synthase
  2. AIRS
  3. Phosphoribosyl-aminoimidazole synthetase
Gene Name PURM
Protein Type Unknown
Biological Properties
General Function Not Available
Specific Function Not Available
Pathways
  • Biosynthesis of secondary metabolites
  • IMP biosynthesis via de novo pathway
  • Purine metabolism
Reactions Not Available
GO Classification
Biological Process
'de novo' IMP biosynthetic process
Cellular Component
cytoplasm
Molecular Function
ATP binding
phosphoribosylformylglycinamidine cyclo-ligase activity
Cellular Location Not Available
Gene Properties
Chromosome Location Not Available
Locus Not Available
SNPs Not Available
Gene Sequence Not Available
Protein Properties
Number of Residues 340
Molecular Weight 36601.825
Theoretical pI 4.823
Pfam Domain Function
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence Not Available
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID Q1JJ82
UniProtKB/Swiss-Prot Entry Name PUR5_STRPD
PDB IDs Not Available
GenBank Gene ID Not Available
GeneCard ID Not Available
GenAtlas ID Not Available
HGNC ID Not Available
References
General References
  1. Beres SB, Richter EW, Nagiec MJ, Sumby P, Porcella SF, DeLeo FR, Musser JM: Molecular genetic anatomy of inter- and intraserotype variation in the human bacterial pathogen group A Streptococcus. Proc Natl Acad Sci U S A. 2006 May 2;103(18):7059-64. doi: 10.1073/pnas.0510279103. Epub 2006 Apr 24. [PubMed:16636287 ]