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Identification
HMDB Protein ID HMDBP13474
Secondary Accession Numbers None
Name Phosphoribosylformylglycinamidine cyclo-ligase
Synonyms
  1. AIR synthase
  2. AIRS
  3. Phosphoribosyl-aminoimidazole synthetase
Gene Name PURM
Protein Type Unknown
Biological Properties
General Function Not Available
Specific Function Not Available
Pathways
  • Biosynthesis of secondary metabolites
  • IMP biosynthesis via de novo pathway
  • Purine metabolism
Reactions Not Available
GO Classification
Biological Process
'de novo' IMP biosynthetic process
Cellular Component
cytoplasm
Molecular Function
ATP binding
phosphoribosylformylglycinamidine cyclo-ligase activity
Cellular Location Not Available
Gene Properties
Chromosome Location Not Available
Locus Not Available
SNPs Not Available
Gene Sequence Not Available
Protein Properties
Number of Residues 343
Molecular Weight 37145.79
Theoretical pI 4.673
Pfam Domain Function
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence Not Available
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID Q4L580
UniProtKB/Swiss-Prot Entry Name PUR5_STAHJ
PDB IDs Not Available
GenBank Gene ID Not Available
GeneCard ID Not Available
GenAtlas ID Not Available
HGNC ID Not Available
References
General References
  1. Takeuchi F, Watanabe S, Baba T, Yuzawa H, Ito T, Morimoto Y, Kuroda M, Cui L, Takahashi M, Ankai A, Baba S, Fukui S, Lee JC, Hiramatsu K: Whole-genome sequencing of staphylococcus haemolyticus uncovers the extreme plasticity of its genome and the evolution of human-colonizing staphylococcal species. J Bacteriol. 2005 Nov;187(21):7292-308. doi: 10.1128/JB.187.21.7292-7308.2005. [PubMed:16237012 ]