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Identification
HMDB Protein ID HMDBP13845
Secondary Accession Numbers None
Name 3-deoxy-manno-octulosonate cytidylyltransferase
Synonyms
  1. CMP-2-keto-3-deoxyoctulosonic acid synthase
  2. CKS
  3. CMP-KDO synthase
Gene Name KDSB
Protein Type Unknown
Biological Properties
General Function Not Available
Specific Function Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
Pathways
  • CMP-3-deoxy-D-manno-octulosonate biosynthesis
  • Lipopolysaccharide biosynthesis
Reactions Not Available
GO Classification
Biological Process
CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process
lipopolysaccharide biosynthetic process
Cellular Component
cytoplasm
Molecular Function
3-deoxy-manno-octulosonate cytidylyltransferase activity
Cellular Location Not Available
Gene Properties
Chromosome Location Not Available
Locus Not Available
SNPs Not Available
Gene Sequence Not Available
Protein Properties
Number of Residues 248
Molecular Weight 27418.185
Theoretical pI 5.832
Pfam Domain Function
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence Not Available
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID Q5PGF5
UniProtKB/Swiss-Prot Entry Name KDSB_SALPA
PDB IDs Not Available
GenBank Gene ID Not Available
GeneCard ID Not Available
GenAtlas ID Not Available
HGNC ID Not Available
References
General References
  1. McClelland M, Sanderson KE, Clifton SW, Latreille P, Porwollik S, Sabo A, Meyer R, Bieri T, Ozersky P, McLellan M, Harkins CR, Wang C, Nguyen C, Berghoff A, Elliott G, Kohlberg S, Strong C, Du F, Carter J, Kremizki C, Layman D, Leonard S, Sun H, Fulton L, Nash W, Miner T, Minx P, Delehaunty K, Fronick C, Magrini V, Nhan M, Warren W, Florea L, Spieth J, Wilson RK: Comparison of genome degradation in Paratyphi A and Typhi, human-restricted serovars of Salmonella enterica that cause typhoid. Nat Genet. 2004 Dec;36(12):1268-74. doi: 10.1038/ng1470. Epub 2004 Nov 7. [PubMed:15531882 ]