Hmdb loader
Identification
HMDB Protein ID HMDBP13855
Secondary Accession Numbers None
Name UDP-3-O-acylglucosamine N-acyltransferase
Synonyms Not Available
Gene Name LPXD
Protein Type Unknown
Biological Properties
General Function Not Available
Specific Function Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Pathways
  • Lipopolysaccharide biosynthesis
  • LPS lipid A biosynthesis
Reactions Not Available
GO Classification
Biological Process
lipid A biosynthetic process
Molecular Function
N-acyltransferase activity
Cellular Location Not Available
Gene Properties
Chromosome Location Not Available
Locus Not Available
SNPs Not Available
Gene Sequence Not Available
Protein Properties
Number of Residues 346
Molecular Weight 36893.065
Theoretical pI 6.461
Pfam Domain Function
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence Not Available
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID A6KWL3
UniProtKB/Swiss-Prot Entry Name LPXD_BACV8
PDB IDs Not Available
GenBank Gene ID Not Available
GeneCard ID Not Available
GenAtlas ID Not Available
HGNC ID Not Available
References
General References
  1. Xu J, Mahowald MA, Ley RE, Lozupone CA, Hamady M, Martens EC, Henrissat B, Coutinho PM, Minx P, Latreille P, Cordum H, Van Brunt A, Kim K, Fulton RS, Fulton LA, Clifton SW, Wilson RK, Knight RD, Gordon JI: Evolution of symbiotic bacteria in the distal human intestine. PLoS Biol. 2007 Jul;5(7):e156. doi: 10.1371/journal.pbio.0050156. Epub 2007 Jun 19. [PubMed:17579514 ]