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Identification
HMDB Protein ID HMDBP13916
Secondary Accession Numbers None
Name Glucose-dependent insulinotropic receptor
Synonyms
  1. G-protein coupled receptor 119
Gene Name GPR119
Protein Type Unknown
Biological Properties
General Function Not Available
Specific Function Receptor for the endogenous fatty-acid ethanolamide oleoylethanolamide (OEA) and lysophosphatidylcholine (LPC). Functions as a glucose-dependent insulinotropic receptor. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Seems to act through a G(s) mediated pathway.
Pathways
  • cAMP signaling pathway
  • Insulin secretion
Reactions Not Available
GO Classification
Biological Process
insulin secretion
regulation of metabolic process
adenylate cyclase-activating G-protein coupled receptor signaling pathway
Cellular Component
receptor complex
cytoplasm
plasma membrane
integral to membrane
Molecular Function
phosphatidylcholine binding
G protein-coupled receptor activity
Cellular Location Not Available
Gene Properties
Chromosome Location Not Available
Locus Not Available
SNPs Not Available
Gene Sequence Not Available
Protein Properties
Number of Residues 335
Molecular Weight 36888.36
Theoretical pI 8.824
Pfam Domain Function
Signals Not Available
Transmembrane Regions
  • 13-33;38-58;82-102;126-146;165-185;227-247;263-283;
Protein Sequence Not Available
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID Q8TDV5
UniProtKB/Swiss-Prot Entry Name GP119_HUMAN
PDB IDs Not Available
GenBank Gene ID Not Available
GeneCard ID Not Available
GenAtlas ID Not Available
HGNC ID Not Available
References
General References
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