| Identification |
|---|
| HMDB Protein ID
| HMDBP13977 |
| Secondary Accession Numbers
| None |
| Name
| Neuromedin-K receptor |
| Synonyms
|
- NKR
- NK-3 receptor
- Neurokinin B receptor
- Tachykinin receptor 3
- NK-3R
|
| Gene Name
| TACR3 |
| Protein Type
| Unknown |
| Biological Properties |
|---|
| General Function
| Not Available |
| Specific Function
| This is a receptor for the tachykinin neuropeptide neuromedin-K (neurokinin B). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
| Biological Process |
| G-protein coupled receptor signaling pathway |
| cell surface receptor signaling pathway |
| Cellular Component |
| integral to plasma membrane |
| Molecular Function |
| tachykinin receptor activity |
| transmembrane signaling receptor activity |
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| Not Available |
| Gene Sequence
|
Not Available
|
| Protein Properties |
|---|
| Number of Residues
| Not Available |
| Molecular Weight
| 49431.305 |
| Theoretical pI
| Not Available |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
- 60-82;93-114;135-156;177-197;221-245;275-296;310-334;
|
| Protein Sequence
|
Not Available
|
| External Links |
|---|
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| P30098 |
| UniProtKB/Swiss-Prot Entry Name
| NK3R_CAVPO |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| Not Available |
| GeneCard ID
| Not Available |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| - Page NM, Bell NJ: The human tachykinin NK1 (short form) and tachykinin NK4 receptor: a reappraisal. Eur J Pharmacol. 2002 Feb 15;437(1-2):27-30. [PubMed:11864635 ]
- Xie GX, Miyajima A, Goldstein A: Expression cloning of cDNA encoding a seven-helix receptor from human placenta with affinity for opioid ligands. Proc Natl Acad Sci U S A. 1992 May 1;89(9):4124-8. doi: 10.1073/pnas.89.9.4124. [PubMed:1315051 ]
- Donaldson LF, Haskell CA, Hanley MR: Functional characterization by heterologous expression of a novel cloned tachykinin peptide receptor. Biochem J. 1996 Nov 15;320 ( Pt 1):1-5. doi: 10.1042/bj3200001. [PubMed:8947459 ]
|
