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Showing Protein Cupincin (HMDBP13981)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 1 metabolite
Identification
HMDB Protein ID HMDBP13981
Secondary Accession Numbers None
Name Cupincin
Synonyms
  1. 52 kDa globulin-like protein
Gene Name Not Available
Protein Type Unknown
Biological Properties
General Function Not Available
Specific Function Seed storage protein (Probable). Globulin-like protein that acts as zinc metalloprotease. Cleaves specifically between Leu-15 and Tyr-16 of insulin B chain, and Gln-1 and Leu-2 of neurotensin (NT) peptide in vitro. May play a role as an initiating endopeptidase in germinating seeds (PubMed:27064905).
Pathways Not Available
Reactions Not Available
GO Classification
Biological Process
protein homotrimerization
Cellular Component
extracellular space
Molecular Function
IgE binding
nutrient reservoir activity
metalloendopeptidase activity
zinc ion binding
Cellular Location Not Available
Gene Properties
Chromosome Location Not Available
Locus Not Available
SNPs Not Available
Gene Sequence Not Available
Protein Properties
Number of Residues Not Available
Molecular Weight 52059.935
Theoretical pI Not Available
Pfam Domain Function
Signals
  • 1-34;
Transmembrane Regions Not Available
Protein Sequence Not Available
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID B8AL97
UniProtKB/Swiss-Prot Entry Name CUCIN_ORYSI
PDB IDs Not Available
GenBank Gene ID Not Available
GeneCard ID Not Available
GenAtlas ID Not Available
HGNC ID Not Available
References
General References
  1. Yu J, Wang J, Lin W, Li S, Li H, Zhou J, Ni P, Dong W, Hu S, Zeng C, Zhang J, Zhang Y, Li R, Xu Z, Li S, Li X, Zheng H, Cong L, Lin L, Yin J, Geng J, Li G, Shi J, Liu J, Lv H, Li J, Wang J, Deng Y, Ran L, Shi X, Wang X, Wu Q, Li C, Ren X, Wang J, Wang X, Li D, Liu D, Zhang X, Ji Z, Zhao W, Sun Y, Zhang Z, Bao J, Han Y, Dong L, Ji J, Chen P, Wu S, Liu J, Xiao Y, Bu D, Tan J, Yang L, Ye C, Zhang J, Xu J, Zhou Y, Yu Y, Zhang B, Zhuang S, Wei H, Liu B, Lei M, Yu H, Li Y, Xu H, Wei S, He X, Fang L, Zhang Z, Zhang Y, Huang X, Su Z, Tong W, Li J, Tong Z, Li S, Ye J, Wang L, Fang L, Lei T, Chen C, Chen H, Xu Z, Li H, Huang H, Zhang F, Xu H, Li N, Zhao C, Li S, Dong L, Huang Y, Li L, Xi Y, Qi Q, Li W, Zhang B, Hu W, Zhang Y, Tian X, Jiao Y, Liang X, Jin J, Gao L, Zheng W, Hao B, Liu S, Wang W, Yuan L, Cao M, McDermott J, Samudrala R, Wang J, Wong GK, Yang H: The Genomes of Oryza sativa: a history of duplications. PLoS Biol. 2005 Feb;3(2):e38. doi: 10.1371/journal.pbio.0030038. Epub 2005 Feb 1. [PubMed:15685292 ]
  2. Kurokawa S, Nakamura R, Mejima M, Kozuka-Hata H, Kuroda M, Takeyama N, Oyama M, Satoh S, Kiyono H, Masumura T, Teshima R, Yuki Y: MucoRice-cholera toxin B-subunit, a rice-based oral cholera vaccine, down-regulates the expression of alpha-amylase/trypsin inhibitor-like protein family as major rice allergens. J Proteome Res. 2013 Jul 5;12(7):3372-82. doi: 10.1021/pr4002146. Epub 2013 Jun 25. [PubMed:23763241 ]
  3. Sreedhar R, Kaul Tiku P: Cupincin: A Unique Protease Purified from Rice (Oryza sativa L.) Bran Is a New Member of the Cupin Superfamily. PLoS One. 2016 Apr 11;11(4):e0152819. doi: 10.1371/journal.pone.0152819. eCollection 2016. [PubMed:27064905 ]