Identification |
HMDB Protein ID
| HMDBP13996 |
Secondary Accession Numbers
| None |
Name
| Homoserine O-acetyltransferase |
Synonyms
|
- HAT
- Homoserine transacetylase
- HTA
|
Gene Name
| METXA |
Protein Type
| Unknown |
Biological Properties |
General Function
| Not Available |
Specific Function
| Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. |
Pathways
|
- Biosynthesis of amino acids
- Biosynthesis of secondary metabolites
- Cysteine and methionine metabolism
- L-methionine biosynthesis via de novo pathway
- Sulfur metabolism
|
Reactions
| Not Available |
GO Classification
|
Biological Process |
methionine biosynthetic process |
Cellular Component |
cytoplasm |
Molecular Function |
homoserine O-acetyltransferase activity |
|
Cellular Location
|
Not Available
|
Gene Properties |
Chromosome Location
| Not Available |
Locus
| Not Available |
SNPs
| Not Available |
Gene Sequence
|
Not Available
|
Protein Properties |
Number of Residues
| 490 |
Molecular Weight
| 55388.825 |
Theoretical pI
| 6.802 |
Pfam Domain Function
|
|
Signals
|
Not Available
|
Transmembrane Regions
|
Not Available
|
Protein Sequence
|
Not Available
|
External Links |
GenBank ID Protein
| Not Available |
UniProtKB/Swiss-Prot ID
| Q2NGH9 |
UniProtKB/Swiss-Prot Entry Name
| METXA_METST |
PDB IDs
|
Not Available |
GenBank Gene ID
| Not Available |
GeneCard ID
| Not Available |
GenAtlas ID
| Not Available |
HGNC ID
| Not Available |
References |
General References
| - Fricke WF, Seedorf H, Henne A, Kruer M, Liesegang H, Hedderich R, Gottschalk G, Thauer RK: The genome sequence of Methanosphaera stadtmanae reveals why this human intestinal archaeon is restricted to methanol and H2 for methane formation and ATP synthesis. J Bacteriol. 2006 Jan;188(2):642-58. doi: 10.1128/JB.188.2.642-658.2006. [PubMed:16385054 ]
- Bastard K, Perret A, Mariage A, Bessonnet T, Pinet-Turpault A, Petit JL, Darii E, Bazire P, Vergne-Vaxelaire C, Brewee C, Debard A, Pellouin V, Besnard-Gonnet M, Artiguenave F, Medigue C, Vallenet D, Danchin A, Zaparucha A, Weissenbach J, Salanoubat M, de Berardinis V: Parallel evolution of non-homologous isofunctional enzymes in methionine biosynthesis. Nat Chem Biol. 2017 Aug;13(8):858-866. doi: 10.1038/nchembio.2397. Epub 2017 Jun 5. [PubMed:28581482 ]
|