Hmdb loader
Identification
HMDB Protein ID HMDBP14113
Secondary Accession Numbers None
Name STE20-related kinase adapter protein beta
Synonyms
  1. STRAD beta
  2. Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein
  3. CALS-21
  4. ILP-interacting protein
  5. Pseudokinase ALS2CR2
Gene Name STRADB
Protein Type Unknown
Biological Properties
General Function Not Available
Specific Function Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation (By similarity).
Pathways
  • AMPK signaling pathway
  • mTOR signaling pathway
Reactions Not Available
GO Classification
Biological Process
cell cycle arrest
cell morphogenesis
protein export from nucleus
protein phosphorylation
JNK cascade
activation of protein kinase activity
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
Cellular Component
cytosol
cytoplasm
aggresome
nucleus
Molecular Function
ATP binding
Cellular Location Not Available
Gene Properties
Chromosome Location Not Available
Locus Not Available
SNPs Not Available
Gene Sequence Not Available
Protein Properties
Number of Residues 418
Molecular Weight 47025.975
Theoretical pI 7.007
Pfam Domain Function
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence Not Available
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID Q9C0K7
UniProtKB/Swiss-Prot Entry Name STRAB_HUMAN
PDB IDs Not Available
GenBank Gene ID Not Available
GeneCard ID Not Available
GenAtlas ID Not Available
HGNC ID Not Available
References
General References
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