Hmdb loader
Identification
HMDB Protein ID HMDBP14114
Secondary Accession Numbers None
Name STE20-related kinase adapter protein alpha
Synonyms
  1. STRAD alpha
  2. STE20-related adapter protein
  3. Serologically defined breast cancer antigen NY-BR-96
Gene Name STRADA
Protein Type Unknown
Biological Properties
General Function Not Available
Specific Function Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation.
Pathways
  • AMPK signaling pathway
  • mTOR signaling pathway
Reactions Not Available
GO Classification
Biological Process
cell cycle arrest
protein export from nucleus
protein phosphorylation
activation of protein kinase activity
Cellular Component
cytosol
cytoplasm
nucleus
nucleoplasm
Molecular Function
protein serine/threonine kinase activator activity
ATP binding
kinase binding
protein kinase activator activity
Cellular Location Not Available
Gene Properties
Chromosome Location Not Available
Locus Not Available
SNPs Not Available
Gene Sequence Not Available
Protein Properties
Number of Residues 431
Molecular Weight 48368.59
Theoretical pI 6.48
Pfam Domain Function
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence Not Available
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID Q7RTN6
UniProtKB/Swiss-Prot Entry Name STRAA_HUMAN
PDB IDs
GenBank Gene ID Not Available
GeneCard ID Not Available
GenAtlas ID Not Available
HGNC ID Not Available
References
General References
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