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Identification
HMDB Protein ID HMDBP14203
Secondary Accession Numbers None
Name Phosphoheptose isomerase
Synonyms
  1. Sedoheptulose 7-phosphate isomerase
Gene Name GMHA
Protein Type Unknown
Biological Properties
General Function Not Available
Specific Function Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
Pathways
  • D-glycero-D-manno-heptose 7-phosphate biosynthesis
  • Lipopolysaccharide biosynthesis
  • LPS core biosynthesis
Reactions Not Available
GO Classification
Biological Process
lipopolysaccharide core region biosynthetic process
D-glycero-D-manno-heptose 7-phosphate biosynthetic process
Cellular Component
cytoplasm
Molecular Function
carbohydrate derivative binding
D-sedoheptulose 7-phosphate isomerase activity
zinc ion binding
Cellular Location Not Available
Gene Properties
Chromosome Location Not Available
Locus Not Available
SNPs Not Available
Gene Sequence Not Available
Protein Properties
Number of Residues 192
Molecular Weight 21022.915
Theoretical pI 6.293
Pfam Domain Function
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence Not Available
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID Q9ZKZ1
UniProtKB/Swiss-Prot Entry Name GMHA_HELPJ
PDB IDs Not Available
GenBank Gene ID Not Available
GeneCard ID Not Available
GenAtlas ID Not Available
HGNC ID Not Available
References
General References
  1. Alm RA, Ling LS, Moir DT, King BL, Brown ED, Doig PC, Smith DR, Noonan B, Guild BC, deJonge BL, Carmel G, Tummino PJ, Caruso A, Uria-Nickelsen M, Mills DM, Ives C, Gibson R, Merberg D, Mills SD, Jiang Q, Taylor DE, Vovis GF, Trust TJ: Genomic-sequence comparison of two unrelated isolates of the human gastric pathogen Helicobacter pylori. Nature. 1999 Jan 14;397(6715):176-80. doi: 10.1038/16495. [PubMed:9923682 ]
  2. Valvano MA, Messner P, Kosma P: Novel pathways for biosynthesis of nucleotide-activated glycero-manno-heptose precursors of bacterial glycoproteins and cell surface polysaccharides. Microbiology (Reading). 2002 Jul;148(Pt 7):1979-1989. doi: 10.1099/00221287-148-7-1979. [PubMed:12101286 ]