Hmdb loader
Identification
HMDB Protein ID HMDBP14323
Secondary Accession Numbers None
Name Sialic acid-binding Ig-like lectin 12
Synonyms
  1. Siglec-12
  2. Sialic acid-binding Ig-like lectin-like 1
  3. Siglec-L1
Gene Name SIGLEC12
Protein Type Unknown
Biological Properties
General Function Not Available
Specific Function Putative adhesion molecule that mediates sialic-acid dependent binding to cells. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.
Pathways Not Available
Reactions Not Available
GO Classification
Biological Process
cell adhesion
Cellular Component
plasma membrane
integral to membrane
Molecular Function
carbohydrate binding
sialic acid binding
Cellular Location Not Available
Gene Properties
Chromosome Location Not Available
Locus Not Available
SNPs Not Available
Gene Sequence Not Available
Protein Properties
Number of Residues 597
Molecular Weight 65075.05
Theoretical pI 6.742
Pfam Domain Function
Signals
  • 1-20;
Transmembrane Regions
  • 484-504;
Protein Sequence Not Available
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID Q95LH0
UniProtKB/Swiss-Prot Entry Name SIG12_PANTR
PDB IDs Not Available
GenBank Gene ID Not Available
GeneCard ID Not Available
GenAtlas ID Not Available
HGNC ID Not Available
References
General References
  1. Angata T, Varki NM, Varki A: A second uniquely human mutation affecting sialic acid biology. J Biol Chem. 2001 Oct 26;276(43):40282-7. doi: 10.1074/jbc.M105926200. Epub 2001 Aug 23. [PubMed:11546777 ]