Showing Protein B-cell receptor CD22 (HMDBP14335)
| Identification | |||||||
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| HMDB Protein ID | HMDBP14335 | ||||||
| Secondary Accession Numbers | None | ||||||
| Name | B-cell receptor CD22 | ||||||
| Synonyms |
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| Gene Name | CD22 | ||||||
| Protein Type | Unknown | ||||||
| Biological Properties | |||||||
| General Function | Not Available | ||||||
| Specific Function | Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially binds to alpha-2,6-linked sialic acid (By similarity). Upon ligand-induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling cascade key molecules. | ||||||
| Pathways | Not Available | ||||||
| Reactions | Not Available | ||||||
| GO Classification |
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| Cellular Location | Not Available | ||||||
| Gene Properties | |||||||
| Chromosome Location | Not Available | ||||||
| Locus | Not Available | ||||||
| SNPs | Not Available | ||||||
| Gene Sequence | Not Available | ||||||
| Protein Properties | |||||||
| Number of Residues | Not Available | ||||||
| Molecular Weight | 37756.675 | ||||||
| Theoretical pI | Not Available | ||||||
| Pfam Domain Function |
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| Signals |
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| Transmembrane Regions | Not Available | ||||||
| Protein Sequence | Not Available | ||||||
| External Links | |||||||
| GenBank ID Protein | Not Available | ||||||
| UniProtKB/Swiss-Prot ID | Q9N1E5 | ||||||
| UniProtKB/Swiss-Prot Entry Name | CD22_PANPA | ||||||
| PDB IDs | Not Available | ||||||
| GenBank Gene ID | Not Available | ||||||
| GeneCard ID | Not Available | ||||||
| GenAtlas ID | Not Available | ||||||
| HGNC ID | Not Available | ||||||
| References | |||||||
| General References |
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