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Showing Protein Glycophorin-A (HMDBP14357)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 0 metabolites
Identification
HMDB Protein ID HMDBP14357
Secondary Accession Numbers None
Name Glycophorin-A
Synonyms
  1. MN sialoglycoprotein
  2. PAS-2
  3. Sialoglycoprotein alpha
Gene Name GYPA
Protein Type Unknown
Biological Properties
General Function Not Available
Specific Function Glycophorin A is the major intrinsic membrane protein of the erythrocyte. The N-terminal glycosylated segment, which lies outside the erythrocyte membrane, has MN blood group receptors. Appears to be important for the function of SLC4A1 and is required for high activity of SLC4A1. May be involved in translocation of SLC4A1 to the plasma membrane. Is a receptor for influenza virus. Is a receptor for Plasmodium falciparum erythrocyte-binding antigen 175 (EBA-175); binding of EBA-175 is dependent on sialic acid residues of the O-linked glycans. Appears to be a receptor for Hepatitis A virus (HAV).
Pathways
  • Hematopoietic cell lineage
  • Malaria
Reactions Not Available
GO Classification
Biological Process
leukocyte migration
Cellular Component
cytosol
plasma membrane
nucleoplasm
membrane
integral to plasma membrane
Molecular Function
viral receptor activity
identical protein binding
Cellular Location Not Available
Gene Properties
Chromosome Location Not Available
Locus Not Available
SNPs Not Available
Gene Sequence Not Available
Protein Properties
Number of Residues 117
Molecular Weight 16331.305
Theoretical pI 5.228
Pfam Domain Function Not Available
Signals
  • 1-19;
Transmembrane Regions
  • 92-114;
Protein Sequence Not Available
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID P02724
UniProtKB/Swiss-Prot Entry Name GLPA_HUMAN
PDB IDs
GenBank Gene ID Not Available
GeneCard ID Not Available
GenAtlas ID Not Available
HGNC ID Not Available
References
General References
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