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Identification
HMDB Protein ID HMDBP14435
Secondary Accession Numbers None
Name Glycosyl-4,4'-diaponeurosporenoate acyltransferase
Synonyms Not Available
Gene Name CRTO
Protein Type Unknown
Biological Properties
General Function Not Available
Specific Function Catalyzes the acylation of glycosyl-4,4'-diaponeurosporenoate, i.e. the esterification of glucose at the C6'' position with the carboxyl group of the C(15) fatty acid 12-methyltetradecanoic acid, to yield staphyloxanthin. This is the last step in the biosynthesis of this orange pigment, present in most staphylococci strains (By similarity).
Pathways
  • Biosynthesis of secondary metabolites
  • Carotenoid biosynthesis
  • staphyloxanthin biosynthesis
Reactions Not Available
GO Classification
Biological Process
carotenoid biosynthetic process
Cellular Component
plasma membrane
integral to membrane
Molecular Function
transferase activity, transferring acyl groups
Cellular Location Not Available
Gene Properties
Chromosome Location Not Available
Locus Not Available
SNPs Not Available
Gene Sequence Not Available
Protein Properties
Number of Residues 171
Molecular Weight 21014.02
Theoretical pI 10.382
Pfam Domain Function
Signals
  • 1-25;
Transmembrane Regions
  • 125-144;
Protein Sequence Not Available
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID Q4L979
UniProtKB/Swiss-Prot Entry Name CRTO_STAHJ
PDB IDs Not Available
GenBank Gene ID Not Available
GeneCard ID Not Available
GenAtlas ID Not Available
HGNC ID Not Available
References
General References
  1. Takeuchi F, Watanabe S, Baba T, Yuzawa H, Ito T, Morimoto Y, Kuroda M, Cui L, Takahashi M, Ankai A, Baba S, Fukui S, Lee JC, Hiramatsu K: Whole-genome sequencing of staphylococcus haemolyticus uncovers the extreme plasticity of its genome and the evolution of human-colonizing staphylococcal species. J Bacteriol. 2005 Nov;187(21):7292-308. doi: 10.1128/JB.187.21.7292-7308.2005. [PubMed:16237012 ]