Identification |
HMDB Protein ID
| HMDBP14562 |
Secondary Accession Numbers
| None |
Name
| Transforming growth factor beta receptor type 3 |
Synonyms
|
- TGF-beta receptor type 3
- TGFR-3
- Betaglycan
- Transforming growth factor beta receptor III
- TGF-beta receptor type III
|
Gene Name
| TGFBR3 |
Protein Type
| Unknown |
Biological Properties |
General Function
| Not Available |
Specific Function
| Binds to TGF-beta. Could be involved in capturing and retaining TGF-beta for presentation to the signaling receptors. |
Pathways
|
Not Available
|
Reactions
| Not Available |
GO Classification
|
Biological Process |
signal transduction |
response to follicle-stimulating hormone stimulus |
cell migration |
BMP signaling pathway |
negative regulation of cellular component movement |
epithelial to mesenchymal transition |
angiogenesis |
immune response |
vasculogenesis |
regulation of transforming growth factor beta receptor signaling pathway |
transforming growth factor beta receptor signaling pathway |
intracellular signal transduction |
Cellular Component |
cell surface |
collagen-containing extracellular matrix |
extracellular space |
external side of plasma membrane |
integral to membrane |
Molecular Function |
transforming growth factor beta binding |
transforming growth factor beta-activated receptor activity |
transforming growth factor beta receptor activity, type III |
coreceptor activity |
heparin binding |
type II transforming growth factor beta receptor binding |
glycosaminoglycan binding |
transforming growth factor beta receptor binding |
|
Cellular Location
|
Not Available
|
Gene Properties |
Chromosome Location
| Not Available |
Locus
| Not Available |
SNPs
| Not Available |
Gene Sequence
|
Not Available
|
Protein Properties |
Number of Residues
| 848 |
Molecular Weight
| 93004.025 |
Theoretical pI
| 6.589 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
Not Available
|
External Links |
GenBank ID Protein
| Not Available |
UniProtKB/Swiss-Prot ID
| P35054 |
UniProtKB/Swiss-Prot Entry Name
| TGBR3_PIG |
PDB IDs
|
Not Available |
GenBank Gene ID
| Not Available |
GeneCard ID
| Not Available |
GenAtlas ID
| Not Available |
HGNC ID
| Not Available |
References |
General References
| - Moren A, Ichijo H, Miyazono K: Molecular cloning and characterization of the human and porcine transforming growth factor-beta type III receptors. Biochem Biophys Res Commun. 1992 Nov 30;189(1):356-62. doi: 10.1016/0006-291x(92)91566-9. [PubMed:1333192 ]
|