Showing Protein Protein-L-histidine N-pros-methyltransferase (HMDBP14648)
| Identification | |
|---|---|
| HMDB Protein ID | HMDBP14648 |
| Secondary Accession Numbers | None |
| Name | Protein-L-histidine N-pros-methyltransferase |
| Synonyms | Not Available |
| Gene Name | METTL9 |
| Protein Type | Enzyme |
| Biological Properties | |
| General Function | Involved in methyltransferase activity |
| Specific Function | Protein-histidine N-methyltransferase that specifically catalyzes 1-methylhistidine (pros-methylhistidine) methylation of target proteins. Mediates methylation of proteins with a His-x-His (HxH) motif (where 'x' is preferably a small amino acid). Catalyzes methylation of target proteins such as S100A9, NDUFB3, SLC39A5, SLC39A7, ARMC6 and DNAJB12; 1-methylhistidine modification may affect the binding of zinc and other metals to its target proteins. Constitutes the main methyltransferase for the 1-methylhistidine modification in cell. |
| Pathways | Not Available |
| Reactions | Not Available |
| GO Classification | Not Available |
| Cellular Location | Not Available |
| Gene Properties | |
| Chromosome Location | 16 |
| Locus | 16p12.2 |
| SNPs | Not Available |
| Gene Sequence | Not Available |
| Protein Properties | |
| Number of Residues | 318 |
| Molecular Weight | 36.0 |
| Theoretical pI | Not Available |
| Pfam Domain Function | Not Available |
| Signals | Not Available |
| Transmembrane Regions | Not Available |
| Protein Sequence | Not Available |
| External Links | |
| GenBank ID Protein | Not Available |
| UniProtKB/Swiss-Prot ID | Q9H1A3 |
| UniProtKB/Swiss-Prot Entry Name | METL9_HUMAN |
| PDB IDs | Not Available |
| GenBank Gene ID | Not Available |
| GeneCard ID | Not Available |
| GenAtlas ID | Not Available |
| HGNC ID | HGNC:24586 |
| References | |
| General References | Not Available |