Showing Protein G-protein coupled receptor 4 (HMDBP14653)
Identification | |
---|---|
HMDB Protein ID | HMDBP14653 |
Secondary Accession Numbers | None |
Name | G-protein coupled receptor 4 |
Synonyms | Not Available |
Gene Name | GPR4 |
Protein Type | Unknown |
Biological Properties | |
General Function | Not Available |
Specific Function | Proton-sensing G-protein coupled receptor couples to multiple intracellular signaling pathways, including GNAS/cAMP, GNAQ/phospholipase C (PLC), and GNA12/GNA13/Rho pathways. Acidosis-induced GPR4 activation increases paracellular gap formation and permeability of vascular endothelial cells through the GNA12/GNA13/Rho GTPase signaling pathway. In the brain may mediate central respiratory sensitivity to CO2H+. |
Pathways | Not Available |
Reactions | Not Available |
GO Classification | Not Available |
Cellular Location | Not Available |
Gene Properties | |
Chromosome Location | 19 |
Locus | 19q13.32 |
SNPs | Not Available |
Gene Sequence | Not Available |
Protein Properties | |
Number of Residues | 362 |
Molecular Weight | 40.0 |
Theoretical pI | Not Available |
Pfam Domain Function | Not Available |
Signals | Not Available |
Transmembrane Regions | Not Available |
Protein Sequence | Not Available |
External Links | |
GenBank ID Protein | AAA63180.1 |
UniProtKB/Swiss-Prot ID | P46093 |
UniProtKB/Swiss-Prot Entry Name | GPR4_HUMAN |
PDB IDs | Not Available |
GenBank Gene ID | Not Available |
GeneCard ID | Not Available |
GenAtlas ID | Not Available |
HGNC ID | HGNC:4497 |
References | |
General References | Not Available |