Accession NumberHMDB04667
Common_Name13S-hydroxyoctadecadienoic acid
Description13-hydroxyoctadecadienoic acid (13-HODE) is synthesized in the body from linoleic acid. 13-HODE prevents cell adhesion to endothelial cells and can inhibit cancer metastasis. 13-HODE synthesis is enhanced by cyclic AMP. Gamma-linolenic acid, a desaturated metabolite of linoleic acid, causes substantial stimulation of 13-HODE synthesis. A fall in gamma-linolenic acid synthesis with age may be related to the age-related fall in 13-HODE formation. (PMID 9561154)
Chemical_IUPAC_Name(9Z,11E,13S)-13-hydroxyoctadeca-9,11-dienoic acid
Chemical FormulaC18H32O3
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