Accession NumberHMDB03459
Common_NameD-Alanyl-D-alanine
DescriptionThe ATP-dependent carboxylate-amine/thiol ligase superfamily is known to contain enzymes catalyzing the formation of various types of peptide, one of which is d-alanyl-d-alanine.(PMID: 16030213) The glycopeptide antibiotic vancomycin acts by binding to the D-alanyl-D-alanine terminus of the cell wall precursor lipid II in the cytoplasmic membrane.(PMID: 17418637) D-alanine-D-alanine ligase from Thermotoga maritima ATCC 43589 (TmDdl) was a useful biocatalyst for synthesizing D-amino acid dipeptides.D-Alanine-D-alanine ligase (Ddl) catalyzes the biosynthesis of an essential bacterial peptidoglycan precursor D-alanyl-D-alanine and it represents an important target for development of new antibacterial drugs. (PMID: 17267218)
Chemical_IUPAC_Name(2R)-2-[[(2R)-2-aminopropanoyl]amino]propanoic acid
Chemical FormulaC6H12N2O3
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Predicted 1H NMR SpectrumDownload
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Predicted 13C NMR PeaklistDownload
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