| Accession Number | HMDB00001 |
| Common_Name | 1-Methylhistidine |
| Description | One-methylhistidine (1-MHis) is derived mainly from the anserine of dietary flesh sources, especially poultry. The enzyme, carnosinase, splits anserine into b-alanine and 1-MHis. High levels of 1-MHis tend to inhibit the enzyme carnosinase and increase anserine levels. Conversely, genetic variants with deficient carnosinase activity in plasma show increased 1-MHis excretions when they consume a high meat diet. Reduced serum carnosinase activity is also found in patients with Parkinson's disease and multiple sclerosis and patients following a cerebrovascular accident. Vitamin E deficiency can lead to 1-methylhistidinuria from increased oxidative effects in skeletal muscle. |
| Chemical_IUPAC_Name | (2S)-2-amino-3-(1-methylimidazol-4-yl)propanoic acid |
| Chemical Formula | C7H11N3O2 |
| Sample Concentration | Not Available |
| Mass Value | 1 |
| Mass Unit | mg |
| Manufacturer | Quattro_QQQ |
| Analyzer | Triple_Quad |
| Delivery | LC |
| Ionization | Positive |
| Predicted 1H NMR Spectrum | Download |
| Predicted 1H NMR Peaklist | Download |
| Predicted 13C NMR Spectrum | Download |
| Predicted 13C NMR Peaklist | Download |
| Sample Concentration | Not Available |
| Mass Value | Not Available |
| Mass Unit | Not Available |
| Manufacturer | Not Available |
| Frequency | Not Available |
| 1H NMR Spectrum |  |
| Sample Concentration | Not Available |
| Mass Value | Not Available |
| Mass Unit | Not Available |
| Manufacturer | Not Available |
| Frequency | Not Available |
| 13C NMR Spectrum | Not Available |
| Low Energy Voltage | 10 |
| Low Energy Spectrum | Download |
| Low Energy Peaklist | Download |
| Medium Energy Spectrum | Download |
| Medium Energy Peaklist | >>>Download |
| High Energy Spectrum | Download |
| High Energy Peaklist | >>>Download |
