Accession NumberHMDB02084
Common_NameCyanide
DescriptionCyanide is an irreversible enzyme inhibitor. Cyanide ions bind to the iron atom of the enzyme cytochrome c oxidase (also known as aa3) in the fourth complex in the mitochondrial membrane in the mitochondria of cells. This denatures the enzyme, and the final transport of electrons from cytochrome c oxidase to oxygen cannot be completed. As a result, the electron transport chain is disrupted, meaning that the cell can no longer aerobically produce ATP for energy. Hydrogen cyanide is a product of combustion, including the exhaust of internal combustion engines, tobacco smoke, and especially some plastics derived from acrylonitrile (because of the latter effect, house fires can result in poisonings of the inhabitants.); Cyanide is a versatile, highly toxic and invaluable anion that is widely encountered in all fields of chemistry.
Chemical_IUPAC_Namecyanide
Chemical FormulaCN
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