Accession NumberHMDB00418
Common_Name18-Hydroxycortisol
Description18-Hydroxycortisol is a derivative of cortIsolated It may be synthesized by zona fasciculata 11-beta hydroxylase in normal human adrenal cortex. (PMID 15356073; 1751390) Overproduction of 18-hydroxycortisol is an aid in the detection of Glucocorticoid-remediable aldosteronism which is an inherited form of mineralocorticoid excess associated with moderate overproduction of aldosterone, in which biochemical and clinical remission is dramatically induced by small amounts of glucocorticoids.(PMID: 1879399)
Chemical_IUPAC_Name(11b)-11,17,18,21-tetrahydroxy-Pregn-4-ene-3,20-dione
Chemical FormulaC21H30O6
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Predicted 1H NMR SpectrumDownload
Predicted 1H NMR PeaklistDownload
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Predicted 13C NMR PeaklistDownload
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