Accession Number | HMDB06583 |
Common_Name | Poly-N-acetyllactosamine |
Description | Poly-N-acetyllactosamine is a sequence similarity in the carbohydrate recognition domain of glycoconjugates.
Galectins constitute a family of structurally related beta-galactoside-binding proteins, which are defined by their affinity for poly-N-acetyllactosamine-enriched glycoconjugates and sequence similarities in the carbohydrate recognition domain. By crosslinking specific glycoconjugates, different members of the galectin family behave as pro-inflammatory or anti-inflammatory agents, acting at different levels of acute and chronic inflammatory responses. Galectin-1 contributes to different events associated with cancer biology, including tumour transformation, cell cycle regulation, apoptosis, cell adhesion, migration and inflammation. Repeated N-acetyllactosamine units can represent a pathogen antigen. A monoclonal antibody (MAb H6-3C4) produced by a human-mouse heterohybridoma was established from the peripheral blood lymphocytes of an infertile patient. N-linked carbohydrate present in the molecular structure of male reproductive tract CD52 (mrtCD52) were identified as an antigenic epitope for sperm-immobilizing antibody. (PMID: 16107278, 15785741, 15191517) |
Chemical_IUPAC_Name | N-[(2R,3R,4R,5R)-3,5,6-trihydroxy-1-oxo-4-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-hexan-2-yl]acetamide |
Chemical Formula | C14H25NO11 |
Sample Concentration | Not Available |
Mass Value | Not Available |
Mass Unit | Not Available |
Manufacturer | Not Available |
Analyzer | Not Available |
Delivery | Not Available |
Ionization | Not Available |
Predicted 1H NMR Spectrum | Download |
Predicted 1H NMR Peaklist | Download |
Predicted 13C NMR Spectrum | Download |
Predicted 13C NMR Peaklist | Download |
Sample Concentration | Not Available |
Mass Value | Not Available |
Mass Unit | Not Available |
Manufacturer | Not Available |
Frequency | Not Available |
1H NMR Spectrum | Not Available |
Sample Concentration | Not Available |
Mass Value | Not Available |
Mass Unit | Not Available |
Manufacturer | Not Available |
Frequency | Not Available |
13C NMR Spectrum | Not Available |
Low Energy Voltage | Not Available |
Low Energy Spectrum | Not Available |
Low Energy Peaklist | Not Available |
Medium Energy Spectrum | Not Available |
Hight Energy Spectrum | Not Available |