Accession Number | HMDB01329 |
Common_Name | 2'-Hydroxynicotine |
Description | 2-Hydroxynicotine is a metabolite of the degradation of Nicotine (Nicotine is an alkaloid found in the nightshade family of plants (Solanaceae), predominantly in tobacco, and in lower quantities in tomato, potato, eggplant (aubergine), and green pepper) via a 2'-hydroxylation reaction producing 2'-hydroxynicotine as an intermediate in the cytochrome P450 2A6 [EC 1.14.14.1] catalyzed conversion of nicotine to 4-(methylamino)-1-(3-pyridyl)-1-butanone. 2'-Hydroxynicotine spontaneously yields nicotine-1'(2')-iminium ion, which is in equilibrium with 4-(methylamino)-1-(3-pyridyl)-1-butanone. About 10% of nicotine and metabolites is excreted as 4-oxo-4-(3-pyridyl)butanoate (keto acid) and 4-hydroxy-4-(3-pyridyl)butanoate (hydroxy acid) in the urine of smokers. |
Chemical_IUPAC_Name | 1-methyl-2-pyridin-3-yl-pyrrolidin-2-ol |
Chemical Formula | C10H14N2O |
Sample Concentration | Not Available |
Mass Value | Not Available |
Mass Unit | Not Available |
Manufacturer | Not Available |
Analyzer | Not Available |
Delivery | Not Available |
Ionization | Not Available |
Predicted 1H NMR Spectrum | Download |
Predicted 1H NMR Peaklist | Download |
Predicted 13C NMR Spectrum | Download |
Predicted 13C NMR Peaklist | Download |
Sample Concentration | Not Available |
Mass Value | Not Available |
Mass Unit | Not Available |
Manufacturer | Not Available |
Frequency | Not Available |
1H NMR Spectrum | Not Available |
Sample Concentration | Not Available |
Mass Value | Not Available |
Mass Unit | Not Available |
Manufacturer | Not Available |
Frequency | Not Available |
13C NMR Spectrum | Not Available |
Low Energy Voltage | Not Available |
Low Energy Spectrum | Not Available |
Low Energy Peaklist | Not Available |
Medium Energy Spectrum | Not Available |
Hight Energy Spectrum | Not Available |