Search Results for metabolites
Searching metabolites for histamine returned 108 results.
HMDB0000177
71-00-1
Blood Breast Milk Cerebrospinal Fluid (CSF) Feces Saliva Sweat Urine
(2S)-2-amino-3-(1H-imidazol-5-yl)propanoic acid
Matched description: … Histidine is a precursor for histamine and carnosine biosynthesis. ... Histidine increases histamine in the blood and probably in the brain. ... Low blood histamine with low serum histidine occurs in rheumatoid arthritis patients. …
HMDB0012983
138482-55-0
(2S)-2-[(2S)-2-[(2S,3S)-2-amino-3-methylpentanamido]propanamido]-5-carbamimidamidopentanoic acid
Matched description: … It is a potent histamine releaser in rodents and may serve as an inflammatory mediator. …
HMDB0015600
190786-44-8
Blood Urine
4-{4-[(4-chlorophenyl)(pyridin-2-yl)methoxy]piperidin-1-yl}butanoic acid
Matched description: … Bepotastine is a non-sedating, selective antagonist of the histamine 1 (H1) receptor. …
HMDB0014535
15676-16-1
Blood Urine
N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide
Matched description: … Sulpiride appears to lack effects on norepinephrine, acetylcholine, serotonin, histamine, or gamma-aminobutyric …
HMDB0015620
24219-97-4
Blood Urine
5-methyl-2,5-diazatetracyclo[13.4.0.0²,⁷.0⁸,¹³]nonadeca-1(19),8,10,12,15,17-hexaene
Matched description: … mechanism of therapeutic action is not well understood, although it apparently blocks alpha-adrenergic, histamine …
HMDB0002331
29605-99-0
Blood Urine
2-{1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-imidazol-4-yl}acetic acid
Matched description: … In kidney glomeruli, histamine is predominantly catabolized to acid metabolites of the diamine oxidase …
HMDB0015248
7187-66-8
Blood Urine
3,5-dibenzyl-4-oxo-8λ⁴-thia-3,5-diazatricyclo[6.3.0.0²,⁶]undecan-8-ylium
Matched description: … Additional effects may include direct peripheral vasodilation and release of histamine. …
HMDB0012988
103131-69-7
(2S)-2-[(2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S,3S)-2-amino-3-methylpentanamido]propanamido]-5-carbamimidamidopentanamido]-5-carbamimidamidopentanamido]-3-(1H-imidazol-4-yl)propanoyl]pyrrolidin-2-yl]formamido}-3-(4-hydroxyphenyl)propanamido]-3-phenylpropanamido]-4-methylpentanoic acid
Matched description: … It is a potent histamine releaser in rodents and may serve as an inflammatory mediator. …
HMDB0015589
52468-60-7
Blood Urine
1-[bis(4-fluorophenyl)methyl]-4-[(2E)-3-phenylprop-2-en-1-yl]piperazine
Matched description: … Flunarizine is a selective calcium entry blocker with calmodulin binding properties and histamine H1 …
HMDB0014727
18016-80-3
Blood Urine
3,3-diethyl-1-[(4S,7R)-6-methyl-6,11-diazatetracyclo[7.6.1.0²,⁷.0¹²,¹⁶]hexadeca-1(16),2,9,12,14-pentaen-4-yl]urea
Matched description: … Evidence has also emerged that Lisuride also binds to the Histamine H1 receptor. …
HMDB0001919
76824-35-6
Blood
3-[({2-[(diaminomethylidene)amino]-1,3-thiazol-4-yl}methyl)sulfanyl]-N'-sulfamoylpropanimidamide
Matched description: … Famotidine is a histamine H2-receptor antagonist that inhibits stomach acid production, and is commonly …
HMDB0014905
63-12-7
Blood Urine
3-(diethylcarbamoyl)-9,10-dimethoxy-1H,2H,3H,4H,6H,7H,11bH-pyrido[2,1-a]isoquinolin-2-yl acetate
Matched description: … not known, but presumably benzquinamide works via antagonism of muscarinic acetycholine receptors and histamine …
HMDB0015102
100643-71-8
Blood Urine
13-chloro-2-(piperidin-4-ylidene)-4-azatricyclo[9.4.0.0³,⁸]pentadeca-1(11),3(8),4,6,12,14-hexaene
Matched description: … It is the active descarboethoxy metabolite of loratidine (a second generation histamine). …
HMDB0001944
113-92-8
[3-(4-chlorophenyl)-3-(pyridin-2-yl)propyl]dimethylamine
Matched description: … Chlorpheniramine is a histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria …
HMDB0015474
60-99-1
Blood Urine
[(2R)-3-(2-methoxy-10H-phenothiazin-10-yl)-2-methylpropyl]dimethylamine
Matched description: … It has the histamine-antagonist properties of the antihistamines together with central nervous system …
HMDB0012984
138482-57-2
(2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S,3S)-2-amino-3-methylpentanamido]propanamido]-5-carbamimidamidopentanamido]-5-carbamimidamidopentanamido]-3-(1H-imidazol-4-yl)propanoyl]pyrrolidin-2-yl]formamido}-3-(4-hydroxyphenyl)propanoic acid
Matched description: … It is a potent histamine releaser in rodents and may serve as an inflammatory mediator. …
HMDB0012986
138482-56-1
(2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-(1H-imidazol-4-yl)propanoyl]pyrrolidin-2-yl]formamido}-3-(4-hydroxyphenyl)propanoic acid
Matched description: … It is a potent histamine releaser in rodents and may serve as an inflammatory mediator. …
HMDB0012987
138482-58-3
(2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-(1H-imidazol-4-yl)propanoyl]pyrrolidin-2-yl]formamido}-3-(4-hydroxyphenyl)propanamido]-3-phenylpropanoic acid
Matched description: … It is a potent histamine releaser in rodents and may serve as an inflammatory mediator. …
HMDB0014915
362-29-8
Blood Urine
1-{10-[2-(dimethylamino)propyl]-10H-phenothiazin-2-yl}propan-1-one
Matched description: … Structurally and pharmacologically similar to clozapine, propiomazine binds to alpha(1), dopamine, histamine …
HMDB0012985
123496-28-6
(2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S,3S)-2-amino-3-methylpentanamido]propanamido]-5-carbamimidamidopentanamido]-5-carbamimidamidopentanamido]-3-(1H-imidazol-4-yl)propanoyl]pyrrolidin-2-yl]formamido}-3-(4-hydroxyphenyl)propanamido]-3-phenylpropanoic acid
Matched synonyms: … Histamine-releasing peptide …
Matched description: … It is a potent histamine releaser in rodents and may serve as an inflammatory mediator. …
Matched description: … It is a potent histamine releaser in rodents and may serve as an inflammatory mediator. …
HMDB0015430
15500-66-0
Blood Urine
1-[(1S,2S,4S,5S,7S,10R,11S,13S,14R,15S)-5,14-bis(acetyloxy)-2,15-dimethyl-13-(1-methylpiperidin-1-ium-1-yl)tetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadecan-4-yl]-1-methylpiperidin-1-ium
Matched description: … neuromuscular blocking agent it is more potent than curare but has less effect on the circulatory system and on histamine …
HMDB0015304
83-98-7
Blood Urine
dimethyl({2-[(2-methylphenyl)(phenyl)methoxy]ethyl})amine
Matched description: … [PubChem]Orphenadrine binds and inhibits both histamine H1 receptors and NMDA receptors. …
HMDB0014889
80012-43-7
Blood Urine
2,4-diazatetracyclo[12.4.0.0²,⁶.0⁷,¹²]octadeca-1(18),3,7,9,11,14,16-heptaen-3-amine
Matched description: … stabilizes mast cells by preventing mast cell degranulation to control the allergic response, 2. prevents histamine …
HMDB0014875
569-65-3
Blood Urine
1-[(4-chlorophenyl)(phenyl)methyl]-4-[(3-methylphenyl)methyl]piperazine
Matched description: … It is a histamine H1 antagonist used in the treatment of motion sickness, vertigo, and nausea during …
HMDB0015369
113-59-7
Blood Urine
[3-(2-chloro-9H-thioxanthen-9-ylidene)propyl]dimethylamine
Matched description: … Chlorprothixene exerts strong blocking effects by blocking the 5-HT2 D1, D2, D3, histamine H1, muscarinic …