Record Information |
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Version | 5.0 |
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Status | Expected but not Quantified |
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Creation Date | 2012-09-06 15:16:50 UTC |
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Update Date | 2022-03-07 02:51:42 UTC |
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HMDB ID | HMDB0014695 |
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Secondary Accession Numbers | |
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Metabolite Identification |
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Common Name | Lamotrigine |
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Description | Lamotrigine is an anticonvulsant drug used in the treatment of epilepsy and bipolar disorder. For epilepsy it is used to treat partial seizures, primary and secondary tonic-clonic seizures, and seizures associated with Lennox-Gastaut syndrome. Lamotrigine also acts as a mood stabilizer. It is the first medication since lithium granted Food and Drug Administration (FDA) approval for the maintenance treatment of bipolar type I. Chemically unrelated to other anticonvulsants, lamotrigine has relatively few side-effects and does not require blood monitoring. The exact way lamotrigine works is unknown. [Wikipedia ] |
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Structure | NC1=NC(N)=C(N=N1)C1=C(Cl)C(Cl)=CC=C1 InChI=1S/C9H7Cl2N5/c10-5-3-1-2-4(6(5)11)7-8(12)14-9(13)16-15-7/h1-3H,(H4,12,13,14,16) |
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Synonyms | Value | Source |
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3,5-Diamino-6-(2,3-dichlorophenyl)-1,2,4-triazine | ChEBI | Lamictal | ChEBI | Lamotrigina | ChEBI | Lamotriginum | ChEBI | GW 273293 | HMDB | Labileno | HMDB | 3,5-Diamino-6-(2,3-dichlorophenyl)-as-triazine | HMDB | BW-430C | HMDB | Crisomet | HMDB | Lamiktal | HMDB | BW 430C | HMDB |
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Chemical Formula | C9H7Cl2N5 |
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Average Molecular Weight | 256.091 |
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Monoisotopic Molecular Weight | 255.007850663 |
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IUPAC Name | 6-(2,3-dichlorophenyl)-1,2,4-triazine-3,5-diamine |
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Traditional Name | lamotrigine |
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CAS Registry Number | 84057-84-1 |
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SMILES | NC1=NC(N)=C(N=N1)C1=C(Cl)C(Cl)=CC=C1 |
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InChI Identifier | InChI=1S/C9H7Cl2N5/c10-5-3-1-2-4(6(5)11)7-8(12)14-9(13)16-15-7/h1-3H,(H4,12,13,14,16) |
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InChI Key | PYZRQGJRPPTADH-UHFFFAOYSA-N |
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Chemical Taxonomy |
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Description | Belongs to the class of organic compounds known as dichlorobenzenes. Dichlorobenzenes are compounds containing a benzene with exactly two chlorine atoms attached to it. |
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Kingdom | Organic compounds |
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Super Class | Benzenoids |
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Class | Benzene and substituted derivatives |
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Sub Class | Halobenzenes |
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Direct Parent | Dichlorobenzenes |
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Alternative Parents | |
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Substituents | - 1,2-dichlorobenzene
- Aminotriazine
- Aryl chloride
- Aryl halide
- Triazine
- Imidolactam
- 1,2,4-triazine
- Heteroaromatic compound
- Organoheterocyclic compound
- Azacycle
- Amine
- Primary amine
- Organonitrogen compound
- Organochloride
- Organohalogen compound
- Organopnictogen compound
- Organic nitrogen compound
- Hydrocarbon derivative
- Aromatic heteromonocyclic compound
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Molecular Framework | Aromatic heteromonocyclic compounds |
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External Descriptors | |
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Ontology |
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Physiological effect | Not Available |
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Disposition | |
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Process | Not Available |
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Role | |
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Physical Properties |
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State | Solid |
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Experimental Molecular Properties | Property | Value | Reference |
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Melting Point | 216 - 218 °C (uncorr.) | Not Available | Boiling Point | Not Available | Not Available | Water Solubility | 0.49 g/L | Not Available | LogP | 2.5 | Not Available |
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Experimental Chromatographic Properties | Experimental Collision Cross Sections |
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Predicted Molecular Properties | | Show more...
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Predicted Chromatographic Properties | Predicted Collision Cross SectionsPredicted Kovats Retention IndicesUnderivatizedDerivatizedDerivative Name / Structure | SMILES | Kovats RI Value | Column Type | Reference |
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Lamotrigine,1TMS,isomer #1 | C[Si](C)(C)NC1=NN=C(C2=CC=CC(Cl)=C2Cl)C(N)=N1 | 2462.9 | Semi standard non polar | 33892256 | Lamotrigine,1TMS,isomer #1 | C[Si](C)(C)NC1=NN=C(C2=CC=CC(Cl)=C2Cl)C(N)=N1 | 2262.0 | Standard non polar | 33892256 | Lamotrigine,1TMS,isomer #1 | C[Si](C)(C)NC1=NN=C(C2=CC=CC(Cl)=C2Cl)C(N)=N1 | 4041.4 | Standard polar | 33892256 | Lamotrigine,1TMS,isomer #2 | C[Si](C)(C)NC1=NC(N)=NN=C1C1=CC=CC(Cl)=C1Cl | 2458.3 | Semi standard non polar | 33892256 | Lamotrigine,1TMS,isomer #2 | C[Si](C)(C)NC1=NC(N)=NN=C1C1=CC=CC(Cl)=C1Cl | 2222.7 | Standard non polar | 33892256 | Lamotrigine,1TMS,isomer #2 | C[Si](C)(C)NC1=NC(N)=NN=C1C1=CC=CC(Cl)=C1Cl | 3959.3 | Standard polar | 33892256 | Lamotrigine,2TMS,isomer #1 | C[Si](C)(C)NC1=NN=C(C2=CC=CC(Cl)=C2Cl)C(N[Si](C)(C)C)=N1 | 2391.7 | Semi standard non polar | 33892256 | Lamotrigine,2TMS,isomer #1 | C[Si](C)(C)NC1=NN=C(C2=CC=CC(Cl)=C2Cl)C(N[Si](C)(C)C)=N1 | 2316.5 | Standard non polar | 33892256 | Lamotrigine,2TMS,isomer #1 | C[Si](C)(C)NC1=NN=C(C2=CC=CC(Cl)=C2Cl)C(N[Si](C)(C)C)=N1 | 3713.7 | Standard polar | 33892256 | Lamotrigine,2TMS,isomer #2 | C[Si](C)(C)N(C1=NN=C(C2=CC=CC(Cl)=C2Cl)C(N)=N1)[Si](C)(C)C | 2351.2 | Semi standard non polar | 33892256 | Lamotrigine,2TMS,isomer #2 | C[Si](C)(C)N(C1=NN=C(C2=CC=CC(Cl)=C2Cl)C(N)=N1)[Si](C)(C)C | 2458.5 | Standard non polar | 33892256 | Lamotrigine,2TMS,isomer #2 | C[Si](C)(C)N(C1=NN=C(C2=CC=CC(Cl)=C2Cl)C(N)=N1)[Si](C)(C)C | 3713.1 | Standard polar | 33892256 | Lamotrigine,2TMS,isomer #3 | C[Si](C)(C)N(C1=NC(N)=NN=C1C1=CC=CC(Cl)=C1Cl)[Si](C)(C)C | 2305.8 | Semi standard non polar | 33892256 | Lamotrigine,2TMS,isomer #3 | C[Si](C)(C)N(C1=NC(N)=NN=C1C1=CC=CC(Cl)=C1Cl)[Si](C)(C)C | 2424.0 | Standard non polar | 33892256 | Lamotrigine,2TMS,isomer #3 | C[Si](C)(C)N(C1=NC(N)=NN=C1C1=CC=CC(Cl)=C1Cl)[Si](C)(C)C | 3716.6 | Standard polar | 33892256 | Lamotrigine,3TMS,isomer #1 | C[Si](C)(C)NC1=NC(N([Si](C)(C)C)[Si](C)(C)C)=NN=C1C1=CC=CC(Cl)=C1Cl | 2384.6 | Semi standard non polar | 33892256 | Lamotrigine,3TMS,isomer #1 | C[Si](C)(C)NC1=NC(N([Si](C)(C)C)[Si](C)(C)C)=NN=C1C1=CC=CC(Cl)=C1Cl | 2483.4 | Standard non polar | 33892256 | Lamotrigine,3TMS,isomer #1 | C[Si](C)(C)NC1=NC(N([Si](C)(C)C)[Si](C)(C)C)=NN=C1C1=CC=CC(Cl)=C1Cl | 3218.9 | Standard polar | 33892256 | Lamotrigine,3TMS,isomer #2 | C[Si](C)(C)NC1=NN=C(C2=CC=CC(Cl)=C2Cl)C(N([Si](C)(C)C)[Si](C)(C)C)=N1 | 2379.4 | Semi standard non polar | 33892256 | Lamotrigine,3TMS,isomer #2 | C[Si](C)(C)NC1=NN=C(C2=CC=CC(Cl)=C2Cl)C(N([Si](C)(C)C)[Si](C)(C)C)=N1 | 2470.2 | Standard non polar | 33892256 | Lamotrigine,3TMS,isomer #2 | C[Si](C)(C)NC1=NN=C(C2=CC=CC(Cl)=C2Cl)C(N([Si](C)(C)C)[Si](C)(C)C)=N1 | 3337.3 | Standard polar | 33892256 | Lamotrigine,4TMS,isomer #1 | C[Si](C)(C)N(C1=NN=C(C2=CC=CC(Cl)=C2Cl)C(N([Si](C)(C)C)[Si](C)(C)C)=N1)[Si](C)(C)C | 2465.6 | Semi standard non polar | 33892256 | Lamotrigine,4TMS,isomer #1 | C[Si](C)(C)N(C1=NN=C(C2=CC=CC(Cl)=C2Cl)C(N([Si](C)(C)C)[Si](C)(C)C)=N1)[Si](C)(C)C | 2612.1 | Standard non polar | 33892256 | Lamotrigine,4TMS,isomer #1 | C[Si](C)(C)N(C1=NN=C(C2=CC=CC(Cl)=C2Cl)C(N([Si](C)(C)C)[Si](C)(C)C)=N1)[Si](C)(C)C | 2884.0 | Standard polar | 33892256 | Lamotrigine,1TBDMS,isomer #1 | CC(C)(C)[Si](C)(C)NC1=NN=C(C2=CC=CC(Cl)=C2Cl)C(N)=N1 | 2623.0 | Semi standard non polar | 33892256 | Lamotrigine,1TBDMS,isomer #1 | CC(C)(C)[Si](C)(C)NC1=NN=C(C2=CC=CC(Cl)=C2Cl)C(N)=N1 | 2489.6 | Standard non polar | 33892256 | Lamotrigine,1TBDMS,isomer #1 | CC(C)(C)[Si](C)(C)NC1=NN=C(C2=CC=CC(Cl)=C2Cl)C(N)=N1 | 4014.2 | Standard polar | 33892256 | Lamotrigine,1TBDMS,isomer #2 | CC(C)(C)[Si](C)(C)NC1=NC(N)=NN=C1C1=CC=CC(Cl)=C1Cl | 2590.2 | Semi standard non polar | 33892256 | Lamotrigine,1TBDMS,isomer #2 | CC(C)(C)[Si](C)(C)NC1=NC(N)=NN=C1C1=CC=CC(Cl)=C1Cl | 2447.4 | Standard non polar | 33892256 | Lamotrigine,1TBDMS,isomer #2 | CC(C)(C)[Si](C)(C)NC1=NC(N)=NN=C1C1=CC=CC(Cl)=C1Cl | 3960.8 | Standard polar | 33892256 | Lamotrigine,2TBDMS,isomer #1 | CC(C)(C)[Si](C)(C)NC1=NN=C(C2=CC=CC(Cl)=C2Cl)C(N[Si](C)(C)C(C)(C)C)=N1 | 2755.0 | Semi standard non polar | 33892256 | Lamotrigine,2TBDMS,isomer #1 | CC(C)(C)[Si](C)(C)NC1=NN=C(C2=CC=CC(Cl)=C2Cl)C(N[Si](C)(C)C(C)(C)C)=N1 | 2801.1 | Standard non polar | 33892256 | Lamotrigine,2TBDMS,isomer #1 | CC(C)(C)[Si](C)(C)NC1=NN=C(C2=CC=CC(Cl)=C2Cl)C(N[Si](C)(C)C(C)(C)C)=N1 | 3665.0 | Standard polar | 33892256 | Lamotrigine,2TBDMS,isomer #2 | CC(C)(C)[Si](C)(C)N(C1=NN=C(C2=CC=CC(Cl)=C2Cl)C(N)=N1)[Si](C)(C)C(C)(C)C | 2753.9 | Semi standard non polar | 33892256 | Lamotrigine,2TBDMS,isomer #2 | CC(C)(C)[Si](C)(C)N(C1=NN=C(C2=CC=CC(Cl)=C2Cl)C(N)=N1)[Si](C)(C)C(C)(C)C | 2826.4 | Standard non polar | 33892256 | Lamotrigine,2TBDMS,isomer #2 | CC(C)(C)[Si](C)(C)N(C1=NN=C(C2=CC=CC(Cl)=C2Cl)C(N)=N1)[Si](C)(C)C(C)(C)C | 3610.6 | Standard polar | 33892256 | Lamotrigine,2TBDMS,isomer #3 | CC(C)(C)[Si](C)(C)N(C1=NC(N)=NN=C1C1=CC=CC(Cl)=C1Cl)[Si](C)(C)C(C)(C)C | 2704.2 | Semi standard non polar | 33892256 | Lamotrigine,2TBDMS,isomer #3 | CC(C)(C)[Si](C)(C)N(C1=NC(N)=NN=C1C1=CC=CC(Cl)=C1Cl)[Si](C)(C)C(C)(C)C | 2806.4 | Standard non polar | 33892256 | Lamotrigine,2TBDMS,isomer #3 | CC(C)(C)[Si](C)(C)N(C1=NC(N)=NN=C1C1=CC=CC(Cl)=C1Cl)[Si](C)(C)C(C)(C)C | 3651.1 | Standard polar | 33892256 | Lamotrigine,3TBDMS,isomer #1 | CC(C)(C)[Si](C)(C)NC1=NC(N([Si](C)(C)C(C)(C)C)[Si](C)(C)C(C)(C)C)=NN=C1C1=CC=CC(Cl)=C1Cl | 2952.7 | Semi standard non polar | 33892256 | Lamotrigine,3TBDMS,isomer #1 | CC(C)(C)[Si](C)(C)NC1=NC(N([Si](C)(C)C(C)(C)C)[Si](C)(C)C(C)(C)C)=NN=C1C1=CC=CC(Cl)=C1Cl | 3079.2 | Standard non polar | 33892256 | Lamotrigine,3TBDMS,isomer #1 | CC(C)(C)[Si](C)(C)NC1=NC(N([Si](C)(C)C(C)(C)C)[Si](C)(C)C(C)(C)C)=NN=C1C1=CC=CC(Cl)=C1Cl | 3316.3 | Standard polar | 33892256 | Lamotrigine,3TBDMS,isomer #2 | CC(C)(C)[Si](C)(C)NC1=NN=C(C2=CC=CC(Cl)=C2Cl)C(N([Si](C)(C)C(C)(C)C)[Si](C)(C)C(C)(C)C)=N1 | 2940.6 | Semi standard non polar | 33892256 | Lamotrigine,3TBDMS,isomer #2 | CC(C)(C)[Si](C)(C)NC1=NN=C(C2=CC=CC(Cl)=C2Cl)C(N([Si](C)(C)C(C)(C)C)[Si](C)(C)C(C)(C)C)=N1 | 3080.2 | Standard non polar | 33892256 | Lamotrigine,3TBDMS,isomer #2 | CC(C)(C)[Si](C)(C)NC1=NN=C(C2=CC=CC(Cl)=C2Cl)C(N([Si](C)(C)C(C)(C)C)[Si](C)(C)C(C)(C)C)=N1 | 3406.8 | Standard polar | 33892256 | Lamotrigine,4TBDMS,isomer #1 | CC(C)(C)[Si](C)(C)N(C1=NN=C(C2=CC=CC(Cl)=C2Cl)C(N([Si](C)(C)C(C)(C)C)[Si](C)(C)C(C)(C)C)=N1)[Si](C)(C)C(C)(C)C | 3164.1 | Semi standard non polar | 33892256 | Lamotrigine,4TBDMS,isomer #1 | CC(C)(C)[Si](C)(C)N(C1=NN=C(C2=CC=CC(Cl)=C2Cl)C(N([Si](C)(C)C(C)(C)C)[Si](C)(C)C(C)(C)C)=N1)[Si](C)(C)C(C)(C)C | 3334.6 | Standard non polar | 33892256 | Lamotrigine,4TBDMS,isomer #1 | CC(C)(C)[Si](C)(C)N(C1=NN=C(C2=CC=CC(Cl)=C2Cl)C(N([Si](C)(C)C(C)(C)C)[Si](C)(C)C(C)(C)C)=N1)[Si](C)(C)C(C)(C)C | 3142.4 | Standard polar | 33892256 |
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Spectra |
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| GC-MS SpectraSpectrum Type | Description | Splash Key | Deposition Date | Source | View |
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Predicted GC-MS | Predicted GC-MS Spectrum - Lamotrigine GC-MS (Non-derivatized) - 70eV, Positive | splash10-0a4i-1890000000-760d1195ef5ceae75026 | 2017-09-01 | Wishart Lab | View Spectrum | Predicted GC-MS | Predicted GC-MS Spectrum - Lamotrigine GC-MS (Non-derivatized) - 70eV, Positive | Not Available | 2021-10-12 | Wishart Lab | View Spectrum | Predicted GC-MS | Predicted GC-MS Spectrum - Lamotrigine GC-MS (Non-derivatized) - 70eV, Positive | Not Available | 2021-10-12 | Wishart Lab | View Spectrum |
MS/MS SpectraSpectrum Type | Description | Splash Key | Deposition Date | Source | View |
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Experimental LC-MS/MS | LC-MS/MS Spectrum - Lamotrigine LC-ESI-qTof , Positive-QTOF | splash10-0a4i-2940000000-1a4f3a098b426ac4febb | 2017-09-14 | HMDB team, MONA | View Spectrum | Experimental LC-MS/MS | LC-MS/MS Spectrum - Lamotrigine LC-ESI-QTOF , positive-QTOF | splash10-0a4i-0090000000-0ca7be847ef73a25032b | 2017-09-14 | HMDB team, MONA | View Spectrum | Experimental LC-MS/MS | LC-MS/MS Spectrum - Lamotrigine LC-ESI-ITFT , positive-QTOF | splash10-0c09-0890000000-f7244245bf6816d03dc7 | 2017-09-14 | HMDB team, MONA | View Spectrum | Experimental LC-MS/MS | LC-MS/MS Spectrum - Lamotrigine LC-ESI-ITFT , positive-QTOF | splash10-0a4i-0090000000-97d10d3ad5d45edcaeba | 2017-09-14 | HMDB team, MONA | View Spectrum | Experimental LC-MS/MS | LC-MS/MS Spectrum - Lamotrigine LC-ESI-ITFT , positive-QTOF | splash10-0a4i-0090000000-b2dbf89c13423bc1b59f | 2017-09-14 | HMDB team, MONA | View Spectrum | Experimental LC-MS/MS | LC-MS/MS Spectrum - Lamotrigine LC-ESI-ITFT , positive-QTOF | splash10-0a4i-0090000000-d26cb5886894916aa1d8 | 2017-09-14 | HMDB team, MONA | View Spectrum | Experimental LC-MS/MS | LC-MS/MS Spectrum - Lamotrigine LC-ESI-ITFT , positive-QTOF | splash10-0a4i-0590000000-528845465e0a140f6b60 | 2017-09-14 | HMDB team, MONA | View Spectrum | Experimental LC-MS/MS | LC-MS/MS Spectrum - Lamotrigine LC-ESI-ITFT , positive-QTOF | splash10-0a4i-0930000000-9a68c83a3573a48cf6c2 | 2017-09-14 | HMDB team, MONA | View Spectrum | Experimental LC-MS/MS | LC-MS/MS Spectrum - Lamotrigine LC-ESI-ITFT , positive-QTOF | splash10-0kmi-0900000000-bb97e1aecda1747cbf29 | 2017-09-14 | HMDB team, MONA | View Spectrum | Experimental LC-MS/MS | LC-MS/MS Spectrum - Lamotrigine LC-ESI-ITFT , positive-QTOF | splash10-0a4i-0090000000-97d10d3ad5d45edcaeba | 2017-09-14 | HMDB team, MONA | View Spectrum | Experimental LC-MS/MS | LC-MS/MS Spectrum - Lamotrigine LC-ESI-ITFT , positive-QTOF | splash10-0a4i-0090000000-97d10d3ad5d45edcaeba | 2017-09-14 | HMDB team, MONA | View Spectrum | Experimental LC-MS/MS | LC-MS/MS Spectrum - Lamotrigine LC-ESI-ITFT , positive-QTOF | splash10-0a4i-0090000000-1e756e80b9a7d4b0dd18 | 2017-09-14 | HMDB team, MONA | View Spectrum | Experimental LC-MS/MS | LC-MS/MS Spectrum - Lamotrigine LC-ESI-ITFT , positive-QTOF | splash10-0a4i-0490000000-a29a09ef58e19c7e62e1 | 2017-09-14 | HMDB team, MONA | View Spectrum | Experimental LC-MS/MS | LC-MS/MS Spectrum - Lamotrigine LC-ESI-ITFT , positive-QTOF | splash10-0a4i-0940000000-85279d67921a0106c4e2 | 2017-09-14 | HMDB team, MONA | View Spectrum | Experimental LC-MS/MS | LC-MS/MS Spectrum - Lamotrigine LC-ESI-ITFT , positive-QTOF | splash10-0kmi-0900000000-eba38744d927d1c39a74 | 2017-09-14 | HMDB team, MONA | View Spectrum | Experimental LC-MS/MS | LC-MS/MS Spectrum - Lamotrigine LC-ESI-ITFT , positive-QTOF | splash10-0ab9-0790000000-036c53ed1835e3d33348 | 2017-09-14 | HMDB team, MONA | View Spectrum | Experimental LC-MS/MS | LC-MS/MS Spectrum - Lamotrigine , positive-QTOF | splash10-0a4i-0290000000-26664a56093e292ec551 | 2017-09-14 | HMDB team, MONA | View Spectrum | Experimental LC-MS/MS | LC-MS/MS Spectrum - Lamotrigine , positive-QTOF | splash10-0a4i-0190000000-33187897c9fb0b0a178f | 2017-09-14 | HMDB team, MONA | View Spectrum | Experimental LC-MS/MS | LC-MS/MS Spectrum - Lamotrigine , positive-QTOF | splash10-0a4i-2940000000-1a4f3a098b426ac4febb | 2017-09-14 | HMDB team, MONA | View Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - Lamotrigine 10V, Positive-QTOF | splash10-0a4i-0090000000-4283661a0ad9c11f2e42 | 2016-08-01 | Wishart Lab | View Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - Lamotrigine 20V, Positive-QTOF | splash10-0a4i-0090000000-7f7abcbaad5c89ee8109 | 2016-08-01 | Wishart Lab | View Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - Lamotrigine 40V, Positive-QTOF | splash10-01w0-2490000000-3dbf5856c09bbcdde184 | 2016-08-01 | Wishart Lab | View Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - Lamotrigine 10V, Negative-QTOF | splash10-0udi-0090000000-55f38f4a1708215a2509 | 2016-08-03 | Wishart Lab | View Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - Lamotrigine 20V, Negative-QTOF | splash10-0ug0-0090000000-067db3f005caf26c9b9a | 2016-08-03 | Wishart Lab | View Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - Lamotrigine 40V, Negative-QTOF | splash10-0006-9010000000-87e51d16bdb0c8facd59 | 2016-08-03 | Wishart Lab | View Spectrum |
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Biological Properties |
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Cellular Locations | |
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Biospecimen Locations | |
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Tissue Locations | Not Available |
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Pathways | |
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Normal Concentrations |
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Blood | Expected but not Quantified | Not Quantified | Not Available | Not Available | Taking drug identified by DrugBank entry DB00555 | | details | Urine | Expected but not Quantified | Not Quantified | Not Available | Not Available | Taking drug identified by DrugBank entry DB00555 | | details |
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Abnormal Concentrations |
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| Not Available |
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Predicted Concentrations |
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Blood | 0.000 uM | Adult (>18 years old) | Both | Normal | Predicted based on drug qualities | Blood | 0.000 umol/mmol creatinine | Adult (>18 years old) | Both | Normal | Predicted based on drug qualities |
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Associated Disorders and Diseases |
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Disease References | None |
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Associated OMIM IDs | None |
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External Links |
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DrugBank ID | DB00555 |
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Phenol Explorer Compound ID | Not Available |
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FooDB ID | Not Available |
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KNApSAcK ID | Not Available |
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Chemspider ID | 3741 |
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KEGG Compound ID | Not Available |
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BioCyc ID | Not Available |
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BiGG ID | Not Available |
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Wikipedia Link | Lamotrigine |
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METLIN ID | Not Available |
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PubChem Compound | 3878 |
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PDB ID | Not Available |
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ChEBI ID | 6367 |
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Food Biomarker Ontology | Not Available |
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VMH ID | Not Available |
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MarkerDB ID | Not Available |
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Good Scents ID | Not Available |
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References |
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Synthesis Reference | Not Available |
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Material Safety Data Sheet (MSDS) | Not Available |
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General References | - Jensen TS: Anticonvulsants in neuropathic pain: rationale and clinical evidence. Eur J Pain. 2002;6 Suppl A:61-8. [PubMed:11888243 ]
- Barbosa L, Berk M, Vorster M: A double-blind, randomized, placebo-controlled trial of augmentation with lamotrigine or placebo in patients concomitantly treated with fluoxetine for resistant major depressive episodes. J Clin Psychiatry. 2003 Apr;64(4):403-7. [PubMed:12716240 ]
- Pappagallo M: Newer antiepileptic drugs: possible uses in the treatment of neuropathic pain and migraine. Clin Ther. 2003 Oct;25(10):2506-38. [PubMed:14667954 ]
- Backonja M: Neuromodulating drugs for the symptomatic treatment of neuropathic pain. Curr Pain Headache Rep. 2004 Jun;8(3):212-6. [PubMed:15115640 ]
- Tehrani SP, Daryaafzoon M, Bakhtiarian A, Ejtemaeemehr S, Sahraei H: The effects of lamotrigine on the acquisition and expression of morphine-induced place preference in mice. Pak J Biol Sci. 2009 Jan 1;12(1):33-9. [PubMed:19579915 ]
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