HMDBP00447 | Estradiol 17-beta-dehydrogenase 2 | P37059 | HSD17B2 | 16q24.1-q24.2 | Unknown | Not Available |
HMDBP00449 | UDP-glucuronosyltransferase 2B28 | Q9BY64 | UGT2B28 | 4q13.2 | Enzyme | Not Available |
HMDBP00450 | Estrogen receptor beta | Q92731 | ESR2 | 14q23.2 | Enzyme | - Sasson S: Equilibrium binding analysis of estrogen agonists and antagonists: relation to the activation of the estrogen receptor. Pathol Biol (Paris). 1991 Jan;39(1):59-69. [PubMed:2011412 ]
- Vijayanathan V, Greenfield NJ, Thomas TJ, Ivanova MM, Tyulmenkov VV, Klinge CM, Gallo MA, Thomas T: Effects of estradiol and 4-hydroxytamoxifen on the conformation, thermal stability, and DNA recognition of estrogen receptor beta. Biochem Cell Biol. 2007 Feb;85(1):1-10. [PubMed:17464340 ]
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HMDBP00453 | Estradiol 17-beta-dehydrogenase 8 | Q92506 | HSD17B8 | 6p21.3 | Unknown | Not Available |
HMDBP00454 | Solute carrier organic anion transporter family member 1B1 | Q9Y6L6 | SLCO1B1 | 12p | Transporter | - Tamai I, Nozawa T, Koshida M, Nezu J, Sai Y, Tsuji A: Functional characterization of human organic anion transporting polypeptide B (OATP-B) in comparison with liver-specific OATP-C. Pharm Res. 2001 Sep;18(9):1262-9. [PubMed:11683238 ]
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HMDBP00458 | UDP-glucuronosyltransferase 2B4 | P06133 | UGT2B4 | 4q13 | Enzyme | Not Available |
HMDBP00478 | UDP-glucuronosyltransferase 1-4 | P22310 | UGT1A4 | 2q37 | Enzyme | Not Available |
HMDBP00479 | UDP-glucuronosyltransferase 2B10 | P36537 | UGT2B10 | 4q13.2 | Enzyme | Not Available |
HMDBP00480 | UDP-glucuronosyltransferase 2B7 | P16662 | UGT2B7 | 4q13 | Enzyme | Not Available |
HMDBP00481 | UDP-glucuronosyltransferase 2B15 | P54855 | UGT2B15 | 4q13 | Enzyme | Not Available |
HMDBP00482 | UDP-glucuronosyltransferase 2A1 | Q9Y4X1 | UGT2A1 | 4q13.3 | Enzyme | Not Available |
HMDBP00483 | UDP-glucuronosyltransferase 1-1 | P22309 | UGT1A1 | 2q37 | Enzyme | - Hanioka N, Tanabe N, Jinno H, Tanaka-Kagawa T, Nagaoka K, Naito S, Koeda A, Narimatsu S: Functional characterization of human and cynomolgus monkey UDP-glucuronosyltransferase 1A1 enzymes. Life Sci. 2010 Aug 14;87(7-8):261-8. doi: 10.1016/j.lfs.2010.07.001. Epub 2010 Jul 8. [PubMed:20620155 ]
- Guillemette C, Belanger A, Lepine J: Metabolic inactivation of estrogens in breast tissue by UDP-glucuronosyltransferase enzymes: an overview. Breast Cancer Res. 2004;6(6):246-54. Epub 2004 Sep 27. [PubMed:15535854 ]
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HMDBP00484 | UDP-glucuronosyltransferase 1-9 | O60656 | UGT1A9 | 2q37 | Enzyme | Not Available |
HMDBP00485 | UDP-glucuronosyltransferase 1-8 | Q9HAW9 | UGT1A8 | 2q37 | Enzyme | Not Available |
HMDBP00486 | UDP-glucuronosyltransferase 1-3 | P35503 | UGT1A3 | 2q37 | Enzyme | Not Available |
HMDBP00487 | UDP-glucuronosyltransferase 1-10 | Q9HAW8 | UGT1A10 | 2q37 | Enzyme | Not Available |
HMDBP00488 | UDP-glucuronosyltransferase 2B17 | O75795 | UGT2B17 | 4q13 | Enzyme | Not Available |
HMDBP00489 | UDP-glucuronosyltransferase 1-6 | P19224 | UGT1A6 | 2q37 | Enzyme | Not Available |
HMDBP00490 | UDP-glucuronosyltransferase 1-5 | P35504 | UGT1A5 | 2q37 | Enzyme | Not Available |
HMDBP00491 | UDP-glucuronosyltransferase 2B11 | O75310 | UGT2B11 | 4q13.2 | Enzyme | Not Available |
HMDBP00494 | UDP-glucuronosyltransferase 1-7 | Q9HAW7 | UGT1A7 | 2q37 | Enzyme | Not Available |
HMDBP00547 | Estradiol 17-beta-dehydrogenase 11 | Q8NBQ5 | HSD17B11 | 4q22.1 | Unknown | Not Available |
HMDBP00847 | Estradiol 17-beta-dehydrogenase 1 | P14061 | HSD17B1 | 17q11-q21 | Unknown | Not Available |
HMDBP00848 | 3-keto-steroid reductase | P56937 | HSD17B7 | 1q23 | Unknown | Not Available |
HMDBP01018 | Cytochrome P450 3A4 | P08684 | CYP3A4 | 7q21.1 | Unknown | - Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. doi: 10.1093/nar/gkp970. Epub 2009 Nov 24. [PubMed:19934256 ]
- Lee AJ, Cai MX, Thomas PE, Conney AH, Zhu BT: Characterization of the oxidative metabolites of 17beta-estradiol and estrone formed by 15 selectively expressed human cytochrome p450 isoforms. Endocrinology. 2003 Aug;144(8):3382-98. [PubMed:12865317 ]
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