| HMDBP00087 | Tyrosinase | P14679 | TYR | 11q14-q21 | Unknown | Not Available |
| HMDBP00273 | Tyrosine 3-monooxygenase | P07101 | TH | 11p15.5 | Enzyme | - Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. [PubMed:11752352 ]
- Olsovska J, Novotna J, Flieger M, Spizek J: Assay of tyrosine hydroxylase based on high-performance liquid chromatography separation and quantification of L-dopa and L-tyrosine. Biomed Chromatogr. 2007 Dec;21(12):1252-8. [PubMed:17604359 ]
- Bodnar I, Hechtl D, Szekacs D, Olah M, Nagy GM: Effect of local (intracerebral and intracerebroventricular) administration of tyrosine hydroxylase inhibitor on the neuroendocrine dopaminergic neurons and prolactin release. Ideggyogy Sz. 2007 Mar 30;60(3-4):177-81. [PubMed:17451064 ]
- Rostrup M, Fossbakk A, Hauge A, Kleppe R, Gnaiger E, Haavik J: Oxygen dependence of tyrosine hydroxylase. Amino Acids. 2008 Apr;34(3):455-64. Epub 2007 May 23. [PubMed:17520326 ]
- Richards AB, Scheel TA, Wang K, Henkemeyer M, Kromer LF: EphB1 null mice exhibit neuronal loss in substantia nigra pars reticulata and spontaneous locomotor hyperactivity. Eur J Neurosci. 2007 May;25(9):2619-28. [PubMed:17561836 ]
- Ugriumov MV: [Brain neurons partly expressing monoaminergic phenotype: distribution, development, and functional significance]. Usp Fiziol Nauk. 2007 Apr-Jun;38(2):3-25. [PubMed:17578016 ]
|
| HMDBP00276 | Thyroid peroxidase | P07202 | TPO | 2p25 | Unknown | Not Available |
| HMDBP00277 | Tyrosine aminotransferase | P17735 | TAT | 16q22.1 | Enzyme | - Dong S, Kang S, Gu TL, Kardar S, Fu H, Lonial S, Khoury HJ, Khuri F, Chen J: 14-3-3 Integrates prosurvival signals mediated by the AKT and MAPK pathways in ZNF198-FGFR1-transformed hematopoietic cells. Blood. 2007 Jul 1;110(1):360-9. Epub 2007 Mar 27. [PubMed:17389761 ]
|
| HMDBP00278 | Aromatic-L-amino-acid decarboxylase | P20711 | DDC | 7p12.2 | Enzyme | Not Available |
| HMDBP00280 | Phenylalanine-4-hydroxylase | P00439 | PAH | 12q22-q24.2 | Enzyme | Not Available |
| HMDBP00283 | Aspartate aminotransferase, cytoplasmic | P17174 | GOT1 | 10q24.1-q25.1 | Enzyme | Not Available |
| HMDBP00284 | Aspartate aminotransferase, mitochondrial | P00505 | GOT2 | 16q21 | Enzyme | Not Available |
| HMDBP00606 | Tyrosine--tRNA ligase, cytoplasmic | P54577 | YARS | 1p35.1 | Enzyme | - Bonnefond L, Frugier M, Touze E, Lorber B, Florentz C, Giege R, Rudinger-Thirion J, Sauter C: Tyrosyl-tRNA synthetase: the first crystallization of a human mitochondrial aminoacyl-tRNA synthetase. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Apr 1;63(Pt 4):338-41. Epub 2007 Mar 30. [PubMed:17401211 ]
|
| HMDBP00619 | Tyrosine--tRNA ligase, mitochondrial | Q9Y2Z4 | YARS2 | 12p11.21 | Enzyme | - Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. [PubMed:17139284 ]
- Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. [PubMed:17016423 ]
- Zhang Y, Wang L, Schultz PG, Wilson IA: Crystal structures of apo wild-type M. jannaschii tyrosyl-tRNA synthetase (TyrRS) and an engineered TyrRS specific for O-methyl-L-tyrosine. Protein Sci. 2005 May;14(5):1340-9. [PubMed:15840835 ]
- Kiga D, Sakamoto K, Kodama K, Kigawa T, Matsuda T, Yabuki T, Shirouzu M, Harada Y, Nakayama H, Takio K, Hasegawa Y, Endo Y, Hirao I, Yokoyama S: An engineered Escherichia coli tyrosyl-tRNA synthetase for site-specific incorporation of an unnatural amino acid into proteins in eukaryotic translation and its application in a wheat germ cell-free system. Proc Natl Acad Sci U S A. 2002 Jul 23;99(15):9715-20. Epub 2002 Jul 3. [PubMed:12097643 ]
- Kobayashi T, Nureki O, Ishitani R, Yaremchuk A, Tukalo M, Cusack S, Sakamoto K, Yokoyama S: Structural basis for orthogonal tRNA specificities of tyrosyl-tRNA synthetases for genetic code expansion. Nat Struct Biol. 2003 Jun;10(6):425-32. [PubMed:12754495 ]
|
| HMDBP01112 | Monocarboxylate transporter 8 | P36021 | SLC16A2 | | Transporter | - Friesema EC, Ganguly S, Abdalla A, Manning Fox JE, Halestrap AP, Visser TJ: Identification of monocarboxylate transporter 8 as a specific thyroid hormone transporter. J Biol Chem. 2003 Oct 10;278(41):40128-35. Epub 2003 Jul 18. [PubMed:12871948 ]
|
| HMDBP01450 | Basic fibroblast growth factor receptor 1 | P11362 | FGFR1 | 8p12 | Enzyme | Not Available |
| HMDBP01456 | Epidermal growth factor receptor | P00533 | EGFR | 7p12 | Enzyme | Not Available |
| HMDBP05340 | Monocarboxylate transporter 10 | Q8TF71 | SLC16A10 | 6q21-q22 | Transporter | - Kim DK, Kanai Y, Matsuo H, Kim JY, Chairoungdua A, Kobayashi Y, Enomoto A, Cha SH, Goya T, Endou H: The human T-type amino acid transporter-1: characterization, gene organization, and chromosomal location. Genomics. 2002 Jan;79(1):95-103. [PubMed:11827462 ]
- Kim DK, Kanai Y, Chairoungdua A, Matsuo H, Cha SH, Endou H: Expression cloning of a Na+-independent aromatic amino acid transporter with structural similarity to H+/monocarboxylate transporters. J Biol Chem. 2001 May 18;276(20):17221-8. Epub 2001 Feb 20. [PubMed:11278508 ]
|
| HMDBP08281 | L-amino-acid oxidase | Q96RQ9 | IL4I1 | 19q13.3-q13.4 | Unknown | Not Available |
| HMDBP08295 | Iodotyrosine dehalogenase 1 | Q6PHW0 | IYD | 6q25.1 | Unknown | Not Available |
| HMDBP08831 | Tubulin--tyrosine ligase | Q8NG68 | TTL | 2q13 | Unknown | Not Available |
