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Record Information
Version5.0
StatusExpected but not Quantified
Creation Date2005-11-16 15:48:42 UTC
Update Date2021-09-14 15:44:39 UTC
HMDB IDHMDB0001076
Secondary Accession Numbers
  • HMDB0062538
  • HMDB01076
  • HMDB62538
Metabolite Identification
Common NameFructose 1-phosphate
DescriptionFructose 1-phosphate, also known as D-fructose-1-p, belongs to the class of organic compounds known as hexose phosphates. These are carbohydrate derivatives containing a hexose substituted by one or more phosphate groups. Metabolism of fructose thus essentially results in intermediates of glycolysis. The final product of glycolysis (pyruvate) may then undergo gluconeogenesis, enter the TCA cycle or be stored as fatty acids. Fructose 1-phosphate exists in all living organisms, ranging from bacteria to humans. Within humans, fructose 1-phosphate participates in a number of enzymatic reactions. In particular, fructose 1-phosphate can be biosynthesized from D-fructose through the action of the enzyme ketohexokinase. In addition, fructose 1-phosphate can be converted into dihydroxyacetone phosphate and glyceraldehyde; which is catalyzed by the enzyme fructose-bisphosphate aldolase a. Because fructokinase has a high Vmax fructose entering cells is quickly phosphorylated to fructose 1-phosphate. In humans, fructose 1-phosphate is involved in fructose intolerance, hereditary. Hypoglycemia results from inhibition of glycogenolysis and gluconeogenesis. It is generated mainly by hepatic fructokinase but is also generated in smaller amounts in the small intestinal mucosa and proximal epithelium of the renal tubule. Aldolase B converts it into glyceraldehyde and dihydroxyacetone phosphate (DHAP). Symptoms of hereditary fructose intolerance are apathy, drowsiness, sweatiness and tremulousness.
Structure
Data?1582752175
Synonyms
ValueSource
beta-D-Fructose 1-phosphateChEBI
b-D-Fructose 1-phosphateGenerator
b-D-Fructose 1-phosphoric acidGenerator
beta-D-Fructose 1-phosphoric acidGenerator
Β-D-fructose 1-phosphateGenerator
Β-D-fructose 1-phosphoric acidGenerator
Fructose 1-phosphoric acidGenerator
D-Fructose 1-phosphateHMDB
D-Fructose-1-pHMDB
D-Fructose-1-phosphateHMDB
Fructose-1-pHMDB
Fructose-1-phosphateHMDB
b-D-Fructofuranose 1-phosphateGenerator
b-D-Fructofuranose 1-phosphoric acidGenerator
beta-D-Fructofuranose 1-phosphoric acidGenerator
Β-D-fructofuranose 1-phosphateGenerator
Β-D-fructofuranose 1-phosphoric acidGenerator
Chemical FormulaC6H13O9P
Average Molecular Weight260.1358
Monoisotopic Molecular Weight260.029718526
IUPAC Name{[(2R,3S,4S,5R)-2,3,4-trihydroxy-5-(hydroxymethyl)oxolan-2-yl]methoxy}phosphonic acid
Traditional Name[(2R,3S,4S,5R)-2,3,4-trihydroxy-5-(hydroxymethyl)oxolan-2-yl]methoxyphosphonic acid
CAS Registry Number15978-08-2
SMILES
OC[C@H]1O[C@](O)(COP(O)(O)=O)[C@@H](O)[C@@H]1O
InChI Identifier
InChI=1S/C6H13O9P/c7-1-3-4(8)5(9)6(10,15-3)2-14-16(11,12)13/h3-5,7-10H,1-2H2,(H2,11,12,13)/t3-,4-,5+,6-/m1/s1
InChI KeyRHKKZBWRNHGJEZ-ARQDHWQXSA-N
Chemical Taxonomy
Description Belongs to the class of organic compounds known as hexose phosphates. These are carbohydrate derivatives containing a hexose substituted by one or more phosphate groups.
KingdomOrganic compounds
Super ClassOrganic oxygen compounds
ClassOrganooxygen compounds
Sub ClassCarbohydrates and carbohydrate conjugates
Direct ParentHexose phosphates
Alternative Parents
Substituents
  • Hexose phosphate
  • Pentose phosphate
  • Pentose-5-phosphate
  • C-glycosyl compound
  • Glycosyl compound
  • Monosaccharide phosphate
  • Pentose monosaccharide
  • Monoalkyl phosphate
  • Organic phosphoric acid derivative
  • Alkyl phosphate
  • Phosphoric acid ester
  • Tetrahydrofuran
  • Secondary alcohol
  • Hemiacetal
  • Organoheterocyclic compound
  • Oxacycle
  • Polyol
  • Alcohol
  • Hydrocarbon derivative
  • Organic oxide
  • Primary alcohol
  • Aliphatic heteromonocyclic compound
Molecular FrameworkAliphatic heteromonocyclic compounds
External DescriptorsNot Available
Ontology
Disposition

Biological location

Source

Route of exposure

Process

Naturally occurring process

Physical Properties
StateSolid
Experimental Molecular Properties
PropertyValueReference
Melting PointNot AvailableNot Available
Boiling PointNot AvailableNot Available
Water SolubilityNot AvailableNot Available
LogPNot AvailableNot Available
Experimental Spectral Properties

Experimental Collision Cross Sections

PredictorAdduct TypeData SourceCCS Value (Å2)Reference
DeepCCS[M-H]-MetCCS_train_neg141.85930932474
AllCCS[M-H]-Not Available141.859http://allccs.zhulab.cn/database/detail?ID=AllCCS00000384
Predicted Molecular Properties
PropertyValueSource
Water Solubility33.4 g/LALOGPS
logP10(-2.1) g/LALOGPS
logP10(-2.9) g/LChemAxon
logS10(-0.89) g/LALOGPS
pKa (Strongest Acidic)1.16ChemAxon
pKa (Strongest Basic)-3ChemAxon
Physiological Charge-2ChemAxon
Hydrogen Acceptor Count8ChemAxon
Hydrogen Donor Count6ChemAxon
Polar Surface Area156.91 ŲChemAxon
Rotatable Bond Count4ChemAxon
Refractivity47.23 m³·mol⁻¹ChemAxon
Polarizability21.06 ųChemAxon
Number of Rings1ChemAxon
BioavailabilityYesChemAxon
Rule of FiveNoChemAxon
Ghose FilterNoChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleNoChemAxon
Predicted Spectral Properties

Predicted Collision Cross Sections

PredictorAdduct TypeCCS Value (Å2)Reference
DarkChem[M+H]+157.48631661259
DarkChem[M-H]-147.59631661259
AllCCS[M+H]+155.60732859911
AllCCS[M-H]-147.21632859911

Predicted Kovats Retention Indices

Derivatized

Derivative Name / StructureSMILESKovats RI ValueColumn TypeReference
Fructose 1-phosphate,1TMS,#1C[Si](C)(C)OC[C@H]1O[C@](O)(COP(=O)(O)O)[C@@H](O)[C@@H]1O2249.3Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,1TMS,#2C[Si](C)(C)O[C@]1(COP(=O)(O)O)O[C@H](CO)[C@@H](O)[C@@H]1O2260.9Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,1TMS,#3C[Si](C)(C)O[C@H]1[C@H](O)[C@@H](CO)O[C@]1(O)COP(=O)(O)O2245.7Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,1TMS,#4C[Si](C)(C)O[C@H]1[C@H](O)[C@@](O)(COP(=O)(O)O)O[C@@H]1CO2242.7Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,1TMS,#5C[Si](C)(C)OP(=O)(O)OC[C@@]1(O)O[C@H](CO)[C@@H](O)[C@@H]1O2292.1Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,2TMS,#1C[Si](C)(C)OC[C@H]1O[C@@](COP(=O)(O)O)(O[Si](C)(C)C)[C@@H](O)[C@@H]1O2246.3Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,2TMS,#2C[Si](C)(C)OC[C@H]1O[C@](O)(COP(=O)(O)O)[C@@H](O[Si](C)(C)C)[C@@H]1O2225.3Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,2TMS,#3C[Si](C)(C)OC[C@H]1O[C@](O)(COP(=O)(O)O)[C@@H](O)[C@@H]1O[Si](C)(C)C2217.4Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,2TMS,#4C[Si](C)(C)OC[C@H]1O[C@](O)(COP(=O)(O)O[Si](C)(C)C)[C@@H](O)[C@@H]1O2284.7Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,2TMS,#5C[Si](C)(C)O[C@H]1[C@H](O)[C@](COP(=O)(O)O)(O[Si](C)(C)C)O[C@@H]1CO2248.5Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,2TMS,#6C[Si](C)(C)O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(COP(=O)(O)O)O[Si](C)(C)C2251.0Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,2TMS,#7C[Si](C)(C)O[C@]1(COP(=O)(O)O[Si](C)(C)C)O[C@H](CO)[C@@H](O)[C@@H]1O2292.8Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,2TMS,#8C[Si](C)(C)O[C@H]1[C@H](O[Si](C)(C)C)[C@@H](CO)O[C@]1(O)COP(=O)(O)O2227.2Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,2TMS,#9C[Si](C)(C)O[C@H]1[C@H](O)[C@@H](CO)O[C@]1(O)COP(=O)(O)O[Si](C)(C)C2294.6Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,2TMS,#10C[Si](C)(C)O[C@H]1[C@H](O)[C@@](O)(COP(=O)(O)O[Si](C)(C)C)O[C@@H]1CO2289.3Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,2TMS,#11C[Si](C)(C)OP(=O)(OC[C@@]1(O)O[C@H](CO)[C@@H](O)[C@@H]1O)O[Si](C)(C)C2263.1Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,3TMS,#1C[Si](C)(C)OC[C@H]1O[C@@](COP(=O)(O)O)(O[Si](C)(C)C)[C@@H](O[Si](C)(C)C)[C@@H]1O2246.4Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,3TMS,#2C[Si](C)(C)OC[C@H]1O[C@@](COP(=O)(O)O)(O[Si](C)(C)C)[C@@H](O)[C@@H]1O[Si](C)(C)C2236.0Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,3TMS,#3C[Si](C)(C)OC[C@H]1O[C@@](COP(=O)(O)O[Si](C)(C)C)(O[Si](C)(C)C)[C@@H](O)[C@@H]1O2259.5Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,3TMS,#4C[Si](C)(C)OC[C@H]1O[C@](O)(COP(=O)(O)O)[C@@H](O[Si](C)(C)C)[C@@H]1O[Si](C)(C)C2217.7Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,3TMS,#5C[Si](C)(C)OC[C@H]1O[C@](O)(COP(=O)(O)O[Si](C)(C)C)[C@@H](O[Si](C)(C)C)[C@@H]1O2250.4Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,3TMS,#6C[Si](C)(C)OC[C@H]1O[C@](O)(COP(=O)(O)O[Si](C)(C)C)[C@@H](O)[C@@H]1O[Si](C)(C)C2240.8Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,3TMS,#7C[Si](C)(C)OC[C@H]1O[C@](O)(COP(=O)(O[Si](C)(C)C)O[Si](C)(C)C)[C@@H](O)[C@@H]1O2233.1Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,3TMS,#8C[Si](C)(C)O[C@H]1[C@H](O[Si](C)(C)C)[C@@H](CO)O[C@@]1(COP(=O)(O)O)O[Si](C)(C)C2250.2Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,3TMS,#9C[Si](C)(C)O[C@H]1[C@H](O)[C@](COP(=O)(O)O[Si](C)(C)C)(O[Si](C)(C)C)O[C@@H]1CO2277.6Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,3TMS,#10C[Si](C)(C)O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(COP(=O)(O)O[Si](C)(C)C)O[Si](C)(C)C2271.0Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,3TMS,#11C[Si](C)(C)O[C@]1(COP(=O)(O[Si](C)(C)C)O[Si](C)(C)C)O[C@H](CO)[C@@H](O)[C@@H]1O2271.9Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,3TMS,#12C[Si](C)(C)O[C@H]1[C@H](O[Si](C)(C)C)[C@@H](CO)O[C@]1(O)COP(=O)(O)O[Si](C)(C)C2261.8Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,3TMS,#13C[Si](C)(C)O[C@H]1[C@H](O)[C@@H](CO)O[C@]1(O)COP(=O)(O[Si](C)(C)C)O[Si](C)(C)C2262.0Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,3TMS,#14C[Si](C)(C)O[C@H]1[C@H](O)[C@@](O)(COP(=O)(O[Si](C)(C)C)O[Si](C)(C)C)O[C@@H]1CO2270.6Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,4TMS,#1C[Si](C)(C)OC[C@H]1O[C@@](COP(=O)(O)O)(O[Si](C)(C)C)[C@@H](O[Si](C)(C)C)[C@@H]1O[Si](C)(C)C2226.5Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,4TMS,#2C[Si](C)(C)OC[C@H]1O[C@@](COP(=O)(O)O[Si](C)(C)C)(O[Si](C)(C)C)[C@@H](O[Si](C)(C)C)[C@@H]1O2271.0Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,4TMS,#3C[Si](C)(C)OC[C@H]1O[C@@](COP(=O)(O)O[Si](C)(C)C)(O[Si](C)(C)C)[C@@H](O)[C@@H]1O[Si](C)(C)C2258.8Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,4TMS,#4C[Si](C)(C)OC[C@H]1O[C@@](COP(=O)(O[Si](C)(C)C)O[Si](C)(C)C)(O[Si](C)(C)C)[C@@H](O)[C@@H]1O2258.4Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,4TMS,#5C[Si](C)(C)OC[C@H]1O[C@](O)(COP(=O)(O)O[Si](C)(C)C)[C@@H](O[Si](C)(C)C)[C@@H]1O[Si](C)(C)C2256.8Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,4TMS,#6C[Si](C)(C)OC[C@H]1O[C@](O)(COP(=O)(O[Si](C)(C)C)O[Si](C)(C)C)[C@@H](O[Si](C)(C)C)[C@@H]1O2272.6Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,4TMS,#7C[Si](C)(C)OC[C@H]1O[C@](O)(COP(=O)(O[Si](C)(C)C)O[Si](C)(C)C)[C@@H](O)[C@@H]1O[Si](C)(C)C2266.3Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,4TMS,#8C[Si](C)(C)O[C@H]1[C@H](O[Si](C)(C)C)[C@@H](CO)O[C@@]1(COP(=O)(O)O[Si](C)(C)C)O[Si](C)(C)C2286.4Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,4TMS,#9C[Si](C)(C)O[C@H]1[C@H](O)[C@](COP(=O)(O[Si](C)(C)C)O[Si](C)(C)C)(O[Si](C)(C)C)O[C@@H]1CO2284.5Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,4TMS,#10C[Si](C)(C)O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(COP(=O)(O[Si](C)(C)C)O[Si](C)(C)C)O[Si](C)(C)C2279.4Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,4TMS,#11C[Si](C)(C)O[C@H]1[C@H](O[Si](C)(C)C)[C@@H](CO)O[C@]1(O)COP(=O)(O[Si](C)(C)C)O[Si](C)(C)C2287.8Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,1TBDMS,#1CC(C)(C)[Si](C)(C)OC[C@H]1O[C@](O)(COP(=O)(O)O)[C@@H](O)[C@@H]1O2477.3Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,1TBDMS,#2CC(C)(C)[Si](C)(C)O[C@]1(COP(=O)(O)O)O[C@H](CO)[C@@H](O)[C@@H]1O2493.1Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,1TBDMS,#3CC(C)(C)[Si](C)(C)O[C@H]1[C@H](O)[C@@H](CO)O[C@]1(O)COP(=O)(O)O2489.2Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,1TBDMS,#4CC(C)(C)[Si](C)(C)O[C@H]1[C@H](O)[C@@](O)(COP(=O)(O)O)O[C@@H]1CO2500.9Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,1TBDMS,#5CC(C)(C)[Si](C)(C)OP(=O)(O)OC[C@@]1(O)O[C@H](CO)[C@@H](O)[C@@H]1O2511.8Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,2TBDMS,#1CC(C)(C)[Si](C)(C)OC[C@H]1O[C@@](COP(=O)(O)O)(O[Si](C)(C)C(C)(C)C)[C@@H](O)[C@@H]1O2630.8Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,2TBDMS,#2CC(C)(C)[Si](C)(C)OC[C@H]1O[C@](O)(COP(=O)(O)O)[C@@H](O[Si](C)(C)C(C)(C)C)[C@@H]1O2638.0Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,2TBDMS,#3CC(C)(C)[Si](C)(C)OC[C@H]1O[C@](O)(COP(=O)(O)O)[C@@H](O)[C@@H]1O[Si](C)(C)C(C)(C)C2616.1Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,2TBDMS,#4CC(C)(C)[Si](C)(C)OC[C@H]1O[C@](O)(COP(=O)(O)O[Si](C)(C)C(C)(C)C)[C@@H](O)[C@@H]1O2699.0Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,2TBDMS,#5CC(C)(C)[Si](C)(C)O[C@H]1[C@H](O)[C@](COP(=O)(O)O)(O[Si](C)(C)C(C)(C)C)O[C@@H]1CO2658.3Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,2TBDMS,#6CC(C)(C)[Si](C)(C)O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(COP(=O)(O)O)O[Si](C)(C)C(C)(C)C2661.7Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,2TBDMS,#7CC(C)(C)[Si](C)(C)O[C@]1(COP(=O)(O)O[Si](C)(C)C(C)(C)C)O[C@H](CO)[C@@H](O)[C@@H]1O2707.1Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,2TBDMS,#8CC(C)(C)[Si](C)(C)O[C@H]1[C@H](O[Si](C)(C)C(C)(C)C)[C@@H](CO)O[C@]1(O)COP(=O)(O)O2670.5Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,2TBDMS,#9CC(C)(C)[Si](C)(C)O[C@H]1[C@H](O)[C@@H](CO)O[C@]1(O)COP(=O)(O)O[Si](C)(C)C(C)(C)C2713.9Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,2TBDMS,#10CC(C)(C)[Si](C)(C)O[C@H]1[C@H](O)[C@@](O)(COP(=O)(O)O[Si](C)(C)C(C)(C)C)O[C@@H]1CO2712.1Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,2TBDMS,#11CC(C)(C)[Si](C)(C)OP(=O)(OC[C@@]1(O)O[C@H](CO)[C@@H](O)[C@@H]1O)O[Si](C)(C)C(C)(C)C2694.0Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,3TBDMS,#1CC(C)(C)[Si](C)(C)OC[C@H]1O[C@@](COP(=O)(O)O)(O[Si](C)(C)C(C)(C)C)[C@@H](O[Si](C)(C)C(C)(C)C)[C@@H]1O2830.5Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,3TBDMS,#2CC(C)(C)[Si](C)(C)OC[C@H]1O[C@@](COP(=O)(O)O)(O[Si](C)(C)C(C)(C)C)[C@@H](O)[C@@H]1O[Si](C)(C)C(C)(C)C2821.0Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,3TBDMS,#3CC(C)(C)[Si](C)(C)OC[C@H]1O[C@@](COP(=O)(O)O[Si](C)(C)C(C)(C)C)(O[Si](C)(C)C(C)(C)C)[C@@H](O)[C@@H]1O2885.9Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,3TBDMS,#4CC(C)(C)[Si](C)(C)OC[C@H]1O[C@](O)(COP(=O)(O)O)[C@@H](O[Si](C)(C)C(C)(C)C)[C@@H]1O[Si](C)(C)C(C)(C)C2825.9Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,3TBDMS,#5CC(C)(C)[Si](C)(C)OC[C@H]1O[C@](O)(COP(=O)(O)O[Si](C)(C)C(C)(C)C)[C@@H](O[Si](C)(C)C(C)(C)C)[C@@H]1O2885.1Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,3TBDMS,#6CC(C)(C)[Si](C)(C)OC[C@H]1O[C@](O)(COP(=O)(O)O[Si](C)(C)C(C)(C)C)[C@@H](O)[C@@H]1O[Si](C)(C)C(C)(C)C2876.3Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,3TBDMS,#7CC(C)(C)[Si](C)(C)OC[C@H]1O[C@](O)(COP(=O)(O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C)[C@@H](O)[C@@H]1O2881.1Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,3TBDMS,#8CC(C)(C)[Si](C)(C)O[C@H]1[C@H](O[Si](C)(C)C(C)(C)C)[C@@H](CO)O[C@@]1(COP(=O)(O)O)O[Si](C)(C)C(C)(C)C2852.7Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,3TBDMS,#9CC(C)(C)[Si](C)(C)O[C@H]1[C@H](O)[C@](COP(=O)(O)O[Si](C)(C)C(C)(C)C)(O[Si](C)(C)C(C)(C)C)O[C@@H]1CO2895.7Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,3TBDMS,#10CC(C)(C)[Si](C)(C)O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(COP(=O)(O)O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C2892.5Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,3TBDMS,#11CC(C)(C)[Si](C)(C)O[C@]1(COP(=O)(O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C)O[C@H](CO)[C@@H](O)[C@@H]1O2903.8Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,3TBDMS,#12CC(C)(C)[Si](C)(C)O[C@H]1[C@H](O[Si](C)(C)C(C)(C)C)[C@@H](CO)O[C@]1(O)COP(=O)(O)O[Si](C)(C)C(C)(C)C2894.6Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,3TBDMS,#13CC(C)(C)[Si](C)(C)O[C@H]1[C@H](O)[C@@H](CO)O[C@]1(O)COP(=O)(O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C2888.9Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,3TBDMS,#14CC(C)(C)[Si](C)(C)O[C@H]1[C@H](O)[C@@](O)(COP(=O)(O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C)O[C@@H]1CO2899.3Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,4TBDMS,#1CC(C)(C)[Si](C)(C)OC[C@H]1O[C@@](COP(=O)(O)O)(O[Si](C)(C)C(C)(C)C)[C@@H](O[Si](C)(C)C(C)(C)C)[C@@H]1O[Si](C)(C)C(C)(C)C3049.4Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,4TBDMS,#2CC(C)(C)[Si](C)(C)OC[C@H]1O[C@@](COP(=O)(O)O[Si](C)(C)C(C)(C)C)(O[Si](C)(C)C(C)(C)C)[C@@H](O[Si](C)(C)C(C)(C)C)[C@@H]1O3081.1Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,4TBDMS,#3CC(C)(C)[Si](C)(C)OC[C@H]1O[C@@](COP(=O)(O)O[Si](C)(C)C(C)(C)C)(O[Si](C)(C)C(C)(C)C)[C@@H](O)[C@@H]1O[Si](C)(C)C(C)(C)C3077.5Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,4TBDMS,#4CC(C)(C)[Si](C)(C)OC[C@H]1O[C@@](COP(=O)(O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C)(O[Si](C)(C)C(C)(C)C)[C@@H](O)[C@@H]1O3095.5Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,4TBDMS,#5CC(C)(C)[Si](C)(C)OC[C@H]1O[C@](O)(COP(=O)(O)O[Si](C)(C)C(C)(C)C)[C@@H](O[Si](C)(C)C(C)(C)C)[C@@H]1O[Si](C)(C)C(C)(C)C3081.3Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,4TBDMS,#6CC(C)(C)[Si](C)(C)OC[C@H]1O[C@](O)(COP(=O)(O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C)[C@@H](O[Si](C)(C)C(C)(C)C)[C@@H]1O3092.3Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,4TBDMS,#7CC(C)(C)[Si](C)(C)OC[C@H]1O[C@](O)(COP(=O)(O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C)[C@@H](O)[C@@H]1O[Si](C)(C)C(C)(C)C3077.3Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,4TBDMS,#8CC(C)(C)[Si](C)(C)O[C@H]1[C@H](O[Si](C)(C)C(C)(C)C)[C@@H](CO)O[C@@]1(COP(=O)(O)O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C3095.7Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,4TBDMS,#9CC(C)(C)[Si](C)(C)O[C@H]1[C@H](O)[C@](COP(=O)(O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C)(O[Si](C)(C)C(C)(C)C)O[C@@H]1CO3103.8Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,4TBDMS,#10CC(C)(C)[Si](C)(C)O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(COP(=O)(O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C3102.5Semi standard non polarhttps://arxiv.org/abs/1905.12712
Fructose 1-phosphate,4TBDMS,#11CC(C)(C)[Si](C)(C)O[C@H]1[C@H](O[Si](C)(C)C(C)(C)C)[C@@H](CO)O[C@]1(O)COP(=O)(O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C3098.9Semi standard non polarhttps://arxiv.org/abs/1905.12712
Spectra

GC-MS Spectra

Spectrum TypeDescriptionSplash KeyDeposition DateSourceView
Predicted GC-MSPredicted GC-MS Spectrum - Fructose 1-phosphate GC-MS (Non-derivatized) - 70eV, Positivesplash10-03di-9510000000-71d828159b61f83421182017-09-01Wishart LabView Spectrum
Predicted GC-MSPredicted GC-MS Spectrum - Fructose 1-phosphate GC-MS (4 TMS) - 70eV, Positivesplash10-001i-2912320000-08ffe3d23f5fa5d6162c2017-10-06Wishart LabView Spectrum
Predicted GC-MSPredicted GC-MS Spectrum - Fructose 1-phosphate GC-MS (Non-derivatized) - 70eV, PositiveNot Available2021-10-12Wishart LabView Spectrum
Predicted GC-MSPredicted GC-MS Spectrum - Fructose 1-phosphate GC-MS (Non-derivatized) - 70eV, PositiveNot Available2021-10-12Wishart LabView Spectrum

MS/MS Spectra

Spectrum TypeDescriptionSplash KeyDeposition DateSourceView
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - Fructose 1-phosphate 10V, Positive-QTOFsplash10-03dm-9470000000-18ac582a370338a3f5f12015-09-15Wishart LabView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - Fructose 1-phosphate 20V, Positive-QTOFsplash10-01oy-7390000000-1a5a72af8bb734e50eb82015-09-15Wishart LabView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - Fructose 1-phosphate 40V, Positive-QTOFsplash10-009y-9100000000-4f151f373d7730140f382015-09-15Wishart LabView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - Fructose 1-phosphate 10V, Negative-QTOFsplash10-0a6r-9270000000-5af916340070910082102015-09-15Wishart LabView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - Fructose 1-phosphate 20V, Negative-QTOFsplash10-004i-9000000000-5cf3f457b8c6f6270b682015-09-15Wishart LabView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - Fructose 1-phosphate 40V, Negative-QTOFsplash10-004i-9000000000-4e6feccf18943de8c4192015-09-15Wishart LabView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - Fructose 1-phosphate 10V, Negative-QTOFsplash10-0a4i-1090000000-03030e5df4374fea160c2021-09-21Wishart LabView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - Fructose 1-phosphate 20V, Negative-QTOFsplash10-004j-9140000000-be637d8fd4ff371117c82021-09-21Wishart LabView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - Fructose 1-phosphate 40V, Negative-QTOFsplash10-004i-9010000000-26f483248da003aafbdb2021-09-21Wishart LabView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - Fructose 1-phosphate 10V, Positive-QTOFsplash10-03di-0190000000-6beaa046be46044471be2021-09-25Wishart LabView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - Fructose 1-phosphate 20V, Positive-QTOFsplash10-01p2-6920000000-7fd7dcf4a4f1479d91b12021-09-25Wishart LabView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - Fructose 1-phosphate 40V, Positive-QTOFsplash10-052b-9100000000-60f4d9de70c1b7a7e1de2021-09-25Wishart LabView Spectrum

NMR Spectra

Spectrum TypeDescriptionDeposition DateSourceView
Predicted 1D NMR13C NMR Spectrum (1D, 100 MHz, D2O, predicted)2021-09-29Wishart LabView Spectrum
Predicted 1D NMR1H NMR Spectrum (1D, 100 MHz, D2O, predicted)2021-09-29Wishart LabView Spectrum
Predicted 1D NMR13C NMR Spectrum (1D, 1000 MHz, D2O, predicted)2021-09-29Wishart LabView Spectrum
Predicted 1D NMR1H NMR Spectrum (1D, 1000 MHz, D2O, predicted)2021-09-29Wishart LabView Spectrum
Predicted 1D NMR13C NMR Spectrum (1D, 200 MHz, D2O, predicted)2021-09-29Wishart LabView Spectrum
Predicted 1D NMR1H NMR Spectrum (1D, 200 MHz, D2O, predicted)2021-09-29Wishart LabView Spectrum
Predicted 1D NMR13C NMR Spectrum (1D, 300 MHz, D2O, predicted)2021-09-29Wishart LabView Spectrum
Predicted 1D NMR1H NMR Spectrum (1D, 300 MHz, D2O, predicted)2021-09-29Wishart LabView Spectrum
Predicted 1D NMR13C NMR Spectrum (1D, 400 MHz, D2O, predicted)2021-09-29Wishart LabView Spectrum
Predicted 1D NMR1H NMR Spectrum (1D, 400 MHz, D2O, predicted)2021-09-29Wishart LabView Spectrum
Predicted 1D NMR13C NMR Spectrum (1D, 500 MHz, D2O, predicted)2021-09-29Wishart LabView Spectrum
Predicted 1D NMR1H NMR Spectrum (1D, 500 MHz, D2O, predicted)2021-09-29Wishart LabView Spectrum
Predicted 1D NMR13C NMR Spectrum (1D, 600 MHz, D2O, predicted)2021-09-29Wishart LabView Spectrum
Predicted 1D NMR1H NMR Spectrum (1D, 600 MHz, D2O, predicted)2021-09-29Wishart LabView Spectrum
Predicted 1D NMR13C NMR Spectrum (1D, 700 MHz, D2O, predicted)2021-09-29Wishart LabView Spectrum
Predicted 1D NMR1H NMR Spectrum (1D, 700 MHz, D2O, predicted)2021-09-29Wishart LabView Spectrum
Predicted 1D NMR13C NMR Spectrum (1D, 800 MHz, D2O, predicted)2021-09-29Wishart LabView Spectrum
Predicted 1D NMR1H NMR Spectrum (1D, 800 MHz, D2O, predicted)2021-09-29Wishart LabView Spectrum
Predicted 1D NMR13C NMR Spectrum (1D, 900 MHz, D2O, predicted)2021-09-29Wishart LabView Spectrum
Predicted 1D NMR1H NMR Spectrum (1D, 900 MHz, D2O, predicted)2021-09-29Wishart LabView Spectrum
Biological Properties
Cellular Locations
  • Cytoplasm (predicted from logP)
Biospecimen LocationsNot Available
Tissue Locations
  • Prostate
Pathways
Normal Concentrations
Not Available
Abnormal Concentrations
Not Available
Associated Disorders and Diseases
Disease ReferencesNone
Associated OMIM IDsNone
DrugBank IDNot Available
Phenol Explorer Compound IDNot Available
FooDB IDFDB022410
KNApSAcK IDNot Available
Chemspider ID8575807
KEGG Compound IDC01094
BioCyc IDFRU1P
BiGG ID40936
Wikipedia LinkFructose 1-phosphate
METLIN ID378
PubChem Compound10400369
PDB IDNot Available
ChEBI ID139419
Food Biomarker OntologyNot Available
VMH IDF1P
MarkerDB IDNot Available
Good Scents IDNot Available
References
Synthesis ReferenceHara, Yoshito. Ion exchange separation of fructose 1-phosphate by using borate as the eluant. Journal of Biochemistry (Tokyo, Japan) (1959), 46 571-3.
Material Safety Data Sheet (MSDS)Not Available
General References
  1. Sreekumar A, Poisson LM, Rajendiran TM, Khan AP, Cao Q, Yu J, Laxman B, Mehra R, Lonigro RJ, Li Y, Nyati MK, Ahsan A, Kalyana-Sundaram S, Han B, Cao X, Byun J, Omenn GS, Ghosh D, Pennathur S, Alexander DC, Berger A, Shuster JR, Wei JT, Varambally S, Beecher C, Chinnaiyan AM: Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression. Nature. 2009 Feb 12;457(7231):910-4. doi: 10.1038/nature07762. [PubMed:19212411 ]
  2. Alvarez E, Roncero I, Chowen JA, Vazquez P, Blazquez E: Evidence that glucokinase regulatory protein is expressed and interacts with glucokinase in rat brain. J Neurochem. 2002 Jan;80(1):45-53. [PubMed:11796742 ]
  3. Malaisse WJ: [Metabolic interactions between glucose and fructose]. Bull Mem Acad R Med Belg. 2002;157(7-9):349-52; discussion 352-3. [PubMed:12647375 ]
  4. Watford M: Small amounts of dietary fructose dramatically increase hepatic glucose uptake through a novel mechanism of glucokinase activation. Nutr Rev. 2002 Aug;60(8):253-7. [PubMed:12199300 ]

Enzymes

General function:
Involved in fructose-bisphosphate aldolase activity
Specific function:
Plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein (By similarity).
Gene Name:
ALDOA
Uniprot ID:
P04075
Molecular weight:
39419.675
Reactions
Fructose 1-phosphate → Dihydroxyacetone phosphate + Glyceraldehydedetails
General function:
Involved in fructose-bisphosphate aldolase activity
Specific function:
Not Available
Gene Name:
ALDOC
Uniprot ID:
P09972
Molecular weight:
39455.505
Reactions
Fructose 1-phosphate → Dihydroxyacetone phosphate + Glyceraldehydedetails
General function:
Involved in fructose-bisphosphate aldolase activity
Specific function:
Not Available
Gene Name:
ALDOB
Uniprot ID:
P05062
Molecular weight:
39472.715
Reactions
Fructose 1-phosphate → Dihydroxyacetone phosphate + Glyceraldehydedetails
General function:
Carbohydrate transport and metabolism
Specific function:
Not Available
Gene Name:
KHK
Uniprot ID:
P50053
Molecular weight:
32730.055