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Showing metabocard for Water (HMDB0002111)
Only showing the first 10 proteins. There are 1159 proteins in total.
Enzymes
- General function:
- Involved in hydrolase activity
- Specific function:
- Hydrolyzes extracellular nucleotides into membrane permeable nucleosides.
- Gene Name:
- NT5E
- Uniprot ID:
- P21589
- Molecular weight:
- 57948.125
Reactions
| A 5'-ribonucleotide + Water → a ribonucleoside + Phosphate | details |
| Adenosine monophosphate + Water → Adenosine + Phosphate | details |
| Cytidine monophosphate + Water → Cytidine + Phosphate | details |
| Uridine 5'-monophosphate + Water → Uridine + Phosphate | details |
| Inosinic acid + Water → Inosine + Phosphate | details |
| Guanosine monophosphate + Water → Guanosine + Phosphate | details |
| 5-Thymidylic acid + Water → Thymidine + Phosphate | details |
| dCMP + Water → Deoxycytidine + Phosphate | details |
| 2'-Deoxyguanosine 5'-monophosphate + Water → Deoxyguanosine + Phosphate | details |
| Deoxyadenosine monophosphate + Water → Deoxyadenosine + Phosphate | details |
| beta-nicotinamide D-ribonucleotide + Water → Nicotinamide riboside + Phosphate | details |
| Xanthylic acid + Water → Xanthosine + Phosphate | details |
| nicotinate beta-D-ribonucleotide + Water → Nicotinate D-ribonucleoside + Phosphate | details |
- General function:
- Involved in nucleotide binding
- Specific function:
- Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides. Helps to regulate adenosine levels (By similarity).
- Gene Name:
- NT5C1B
- Uniprot ID:
- Q96P26
- Molecular weight:
- 68803.055
Reactions
| A 5'-ribonucleotide + Water → a ribonucleoside + Phosphate | details |
| Adenosine monophosphate + Water → Adenosine + Phosphate | details |
| Cytidine monophosphate + Water → Cytidine + Phosphate | details |
| Uridine 5'-monophosphate + Water → Uridine + Phosphate | details |
| Inosinic acid + Water → Inosine + Phosphate | details |
| Guanosine monophosphate + Water → Guanosine + Phosphate | details |
| 5-Thymidylic acid + Water → Thymidine + Phosphate | details |
| dCMP + Water → Deoxycytidine + Phosphate | details |
| 2'-Deoxyguanosine 5'-monophosphate + Water → Deoxyguanosine + Phosphate | details |
| Deoxyadenosine monophosphate + Water → Deoxyadenosine + Phosphate | details |
| beta-nicotinamide D-ribonucleotide + Water → Nicotinamide riboside + Phosphate | details |
| Xanthylic acid + Water → Xanthosine + Phosphate | details |
| nicotinate beta-D-ribonucleotide + Water → Nicotinate D-ribonucleoside + Phosphate | details |
- General function:
- Involved in nucleotide binding
- Specific function:
- Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides and has a broad substrate specificity. Helps to regulate adenosine levels in heart during ischemia and hypoxia.
- Gene Name:
- NT5C1A
- Uniprot ID:
- Q9BXI3
- Molecular weight:
- 41020.145
Reactions
| A 5'-ribonucleotide + Water → a ribonucleoside + Phosphate | details |
| Adenosine monophosphate + Water → Adenosine + Phosphate | details |
| Cytidine monophosphate + Water → Cytidine + Phosphate | details |
| Uridine 5'-monophosphate + Water → Uridine + Phosphate | details |
| Inosinic acid + Water → Inosine + Phosphate | details |
| Guanosine monophosphate + Water → Guanosine + Phosphate | details |
| 5-Thymidylic acid + Water → Thymidine + Phosphate | details |
| dCMP + Water → Deoxycytidine + Phosphate | details |
| 2'-Deoxyguanosine 5'-monophosphate + Water → Deoxyguanosine + Phosphate | details |
| Deoxyadenosine monophosphate + Water → Deoxyadenosine + Phosphate | details |
| beta-nicotinamide D-ribonucleotide + Water → Nicotinamide riboside + Phosphate | details |
| Xanthylic acid + Water → Xanthosine + Phosphate | details |
| nicotinate beta-D-ribonucleotide + Water → Nicotinate D-ribonucleoside + Phosphate | details |
- General function:
- Involved in metal ion binding
- Specific function:
- Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides, with a preference for dUMP and dTMP, intermediate activity towards dGMP, and low activity towards dCMP and dAMP.
- Gene Name:
- NT5C
- Uniprot ID:
- Q8TCD5
- Molecular weight:
- Not Available
Reactions
| Adenosine monophosphate + Water → Adenosine + Phosphate | details |
| Cytidine monophosphate + Water → Cytidine + Phosphate | details |
| Uridine 5'-monophosphate + Water → Uridine + Phosphate | details |
| Inosinic acid + Water → Inosine + Phosphate | details |
| Guanosine monophosphate + Water → Guanosine + Phosphate | details |
| 5-Thymidylic acid + Water → Thymidine + Phosphate | details |
| dCMP + Water → Deoxycytidine + Phosphate | details |
| 2'-Deoxyguanosine 5'-monophosphate + Water → Deoxyguanosine + Phosphate | details |
| Deoxyadenosine monophosphate + Water → Deoxyadenosine + Phosphate | details |
| beta-nicotinamide D-ribonucleotide + Water → Nicotinamide riboside + Phosphate | details |
| Xanthylic acid + Water → Xanthosine + Phosphate | details |
| nicotinate beta-D-ribonucleotide + Water → Nicotinate D-ribonucleoside + Phosphate | details |
- General function:
- Involved in phosphatase activity
- Specific function:
- Dephosphorylates specifically the 5' and 2'(3')-phosphates of uracil and thymine deoxyribonucleotides, and so protects mitochondrial DNA replication from excess dTTP. Has only marginal activity towards dIMP and dGMP.
- Gene Name:
- NT5M
- Uniprot ID:
- Q9NPB1
- Molecular weight:
- Not Available
Reactions
| Adenosine monophosphate + Water → Adenosine + Phosphate | details |
| Cytidine monophosphate + Water → Cytidine + Phosphate | details |
| Uridine 5'-monophosphate + Water → Uridine + Phosphate | details |
| Inosinic acid + Water → Inosine + Phosphate | details |
| Guanosine monophosphate + Water → Guanosine + Phosphate | details |
| 5-Thymidylic acid + Water → Thymidine + Phosphate | details |
| dCMP + Water → Deoxycytidine + Phosphate | details |
| 2'-Deoxyguanosine 5'-monophosphate + Water → Deoxyguanosine + Phosphate | details |
| Deoxyadenosine monophosphate + Water → Deoxyadenosine + Phosphate | details |
| beta-nicotinamide D-ribonucleotide + Water → Nicotinamide riboside + Phosphate | details |
| Xanthylic acid + Water → Xanthosine + Phosphate | details |
| nicotinate beta-D-ribonucleotide + Water → Nicotinate D-ribonucleoside + Phosphate | details |
- General function:
- Involved in transferase activity
- Specific function:
- Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. This multifunctional protein has 7 catalytic activities and an acyl carrier protein.
- Gene Name:
- FASN
- Uniprot ID:
- P49327
- Molecular weight:
- 273424.06
Reactions
| A (3R)-3-hydroxyacyl-[acyl-carrier protein] → a trans-2-enoyl-[acyl-carrier protein] + Water | details |
| Oleoyl-[acyl-carrier-protein] + Water → [acyl-carrier-protein] + Oleic acid | details |
| Hexadecanoyl-[acp] + Water → Acyl-carrier protein + Palmitic acid | details |
| (3R)-3-Hydroxybutanoyl-[acyl-carrier protein] → But-2-enoyl-[acyl-carrier protein] + Water | details |
| (3R)-3-Hydroxydecanoyl-[acyl-carrier protein] → trans-Dec-2-enoyl-[acp] + Water | details |
| (3R)-3-Hydroxyoctanoyl-[acyl-carrier protein] → trans-Oct-2-enoyl-[acp] + Water | details |
| (3R)-3-Hydroxypalmitoyl-[acyl-carrier protein] → trans-Hexadec-2-enoyl-[acp] + Water | details |
| (3R)-3-Hydroxytetradecanoyl-[acyl-carrier protein] → trans-Tetradec-2-enoyl-[acp] + Water | details |
| (R)-3-Hydroxyhexanoyl-[acp] → trans-Hex-2-enoyl-[acp] + Water | details |
| (R)-3-Hydroxydodecanoyl-[acp] → trans-Dodec-2-enoyl-[acp] + Water | details |
| Tetradecanoyl-[acp] + Water → Acyl-carrier protein + Myristic acid | details |
- General function:
- Involved in hydroxymethylglutaryl-CoA synthase activity
- Specific function:
- This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
- Gene Name:
- HMGCS2
- Uniprot ID:
- P54868
- Molecular weight:
- 52481.065
Reactions
| Acetyl-CoA + Water + Acetoacetyl-CoA → 3-Hydroxy-3-methylglutaryl-CoA + Coenzyme A | details |
| 3-Hydroxy-3-methylglutaryl-CoA + Coenzyme A → Acetyl-CoA + Water + Acetoacetyl-CoA | details |
- General function:
- Involved in transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer
- Specific function:
- Not Available
- Gene Name:
- CS
- Uniprot ID:
- O75390
- Molecular weight:
- 51712.025
Reactions
| Acetyl-CoA + Water + Oxalacetic acid → Citric acid + Coenzyme A | details |
| Citric acid + Coenzyme A → Acetyl-CoA + Water + Oxalacetic acid | details |
Transporters
- General function:
- Involved in ATP binding
- Specific function:
- Involved in the export of copper out of the cells, such as the efflux of hepatic copper into the bile.
- Gene Name:
- ATP7B
- Uniprot ID:
- P35670
- Molecular weight:
- 157261.34
- General function:
- Involved in ATP binding
- Specific function:
- May supply copper to copper-requiring proteins within the secretory pathway, when localized in the trans-Golgi network. Under conditions of elevated extracellular copper, it relocalized to the plasma membrane where it functions in the efflux of copper from cells.
- Gene Name:
- ATP7A
- Uniprot ID:
- Q04656
- Molecular weight:
- 163372.275
Only showing the first 10 proteins. There are 1159 proteins in total.