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Record Information
Version5.0
StatusDetected and Quantified
Creation Date2006-08-13 10:47:12 UTC
Update Date2021-09-07 16:45:36 UTC
HMDB IDHMDB0004095
Secondary Accession Numbers
  • HMDB04095
Metabolite Identification
Common Name5-Methoxytryptamine
Description5-Methoxytryptamine, also known as mexamine or 5-MT, belongs to the class of organic compounds known as tryptamines and derivatives. Tryptamines and derivatives are compounds containing the tryptamine backbone, which is structurally characterized by an indole ring substituted at the 3-position by an ethanamine. It is biosynthesized via the deacetylation of melatonin in the pineal gland. 5-MT acts as a full agonist at the 5-HT1, 5-HT2, 5-HT4, 5-HT6, and 5-HT7 receptors. 5-Methoxytryptamine exists in all living organisms, ranging from bacteria to humans. Its affinity for the 5-HT5A receptor is unknown. It has no affinity for the 5-HT3 receptor and is affinity for the 5-HT1E receptor is very weak in comparison to the other 5-HT1 receptors. 5-MT has been shown to occur naturally in the body in low levels.
Structure
Data?1582752298
Synonyms
ValueSource
2-(5-Methoxyindol-3-yl)ethylamineChEBI
3-(2-Aminoethyl)-5-methoxyindoleChEBI
5-MeOTChEBI
5-Methoxy-1H-indole-3-ethanamineChEBI
5-MTChEBI
5MOTChEBI
MexamineChEBI
2-(5-Methoxy-1H-indol-3-yl)ethanamineHMDB
5-MotHMDB
Lopac-m-6628HMDB
MeksaminHMDB
MethoxytryptamineHMDB
Mexamine baseHMDB
MeksamineHMDB
5 MethoxytryptamineHMDB
5-MethoxytryptamineChEBI
Chemical FormulaC11H14N2O
Average Molecular Weight190.2417
Monoisotopic Molecular Weight190.11061308
IUPAC Name2-(5-methoxy-1H-indol-3-yl)ethan-1-amine
Traditional Name5 methoxytryptamine
CAS Registry Number608-07-1
SMILES
COC1=CC2=C(NC=C2CCN)C=C1
InChI Identifier
InChI=1S/C11H14N2O/c1-14-9-2-3-11-10(6-9)8(4-5-12)7-13-11/h2-3,6-7,13H,4-5,12H2,1H3
InChI KeyJTEJPPKMYBDEMY-UHFFFAOYSA-N
Chemical Taxonomy
Description Belongs to the class of organic compounds known as tryptamines and derivatives. Tryptamines and derivatives are compounds containing the tryptamine backbone, which is structurally characterized by an indole ring substituted at the 3-position by an ethanamine.
KingdomOrganic compounds
Super ClassOrganoheterocyclic compounds
ClassIndoles and derivatives
Sub ClassTryptamines and derivatives
Direct ParentTryptamines and derivatives
Alternative Parents
Substituents
  • Tryptamine
  • 3-alkylindole
  • Indole
  • Anisole
  • 2-arylethylamine
  • Alkyl aryl ether
  • Aralkylamine
  • Substituted pyrrole
  • Benzenoid
  • Heteroaromatic compound
  • Pyrrole
  • Ether
  • Azacycle
  • Hydrocarbon derivative
  • Organic nitrogen compound
  • Primary amine
  • Organooxygen compound
  • Organonitrogen compound
  • Primary aliphatic amine
  • Organopnictogen compound
  • Organic oxygen compound
  • Amine
  • Aromatic heteropolycyclic compound
Molecular FrameworkAromatic heteropolycyclic compounds
External Descriptors
Ontology
Disposition

Biological location

Source

Route of exposure

Physical Properties
StateSolid
Experimental Molecular Properties
PropertyValueReference
Melting Point121.5 °CNot Available
Boiling PointNot AvailableNot Available
Water SolubilityNot AvailableNot Available
LogPNot AvailableNot Available
Experimental Chromatographic Properties

Experimental Collision Cross Sections

Adduct TypeData SourceCCS Value (Å2)Reference
[M-H]-MetCCS_train_neg141.18230932474
[M-H]-Not Available141.182http://allccs.zhulab.cn/database/detail?ID=AllCCS00000359
Predicted Molecular Properties
PropertyValueSource
Water Solubility0.79 g/LALOGPS
logP10(1.41) g/LALOGPS
logP10(1.33) g/LChemAxon
logS10(-2.4) g/LALOGPS
pKa (Strongest Acidic)17.45ChemAxon
pKa (Strongest Basic)9.76ChemAxon
Physiological Charge1ChemAxon
Hydrogen Acceptor Count2ChemAxon
Hydrogen Donor Count2ChemAxon
Polar Surface Area51.04 ŲChemAxon
Rotatable Bond Count3ChemAxon
Refractivity56.84 m³·mol⁻¹ChemAxon
Polarizability21.32 ųChemAxon
Number of Rings2ChemAxon
BioavailabilityYesChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleNoChemAxon
Predicted Chromatographic Properties

Predicted Collision Cross Sections

PredictorAdduct TypeCCS Value (Å2)Reference
DarkChem[M+H]+141.831661259
DarkChem[M-H]-143.17131661259

Predicted Kovats Retention Indices

Underivatized

MetaboliteSMILESKovats RI ValueColumn TypeReference
5-MethoxytryptamineCOC1=CC2=C(NC=C2CCN)C=C12963.7Standard polar33892256
5-MethoxytryptamineCOC1=CC2=C(NC=C2CCN)C=C11987.9Standard non polar33892256
5-MethoxytryptamineCOC1=CC2=C(NC=C2CCN)C=C12045.3Semi standard non polar33892256

Derivatized

Derivative Name / StructureSMILESKovats RI ValueColumn TypeReference
5-Methoxytryptamine,1TMS,isomer #1COC1=CC=C2[NH]C=C(CCN[Si](C)(C)C)C2=C12089.1Semi standard non polar33892256
5-Methoxytryptamine,1TMS,isomer #1COC1=CC=C2[NH]C=C(CCN[Si](C)(C)C)C2=C12183.0Standard non polar33892256
5-Methoxytryptamine,1TMS,isomer #1COC1=CC=C2[NH]C=C(CCN[Si](C)(C)C)C2=C12684.6Standard polar33892256
5-Methoxytryptamine,1TMS,isomer #2COC1=CC=C2C(=C1)C(CCN)=CN2[Si](C)(C)C2038.7Semi standard non polar33892256
5-Methoxytryptamine,1TMS,isomer #2COC1=CC=C2C(=C1)C(CCN)=CN2[Si](C)(C)C2098.4Standard non polar33892256
5-Methoxytryptamine,1TMS,isomer #2COC1=CC=C2C(=C1)C(CCN)=CN2[Si](C)(C)C2652.5Standard polar33892256
5-Methoxytryptamine,2TMS,isomer #1COC1=CC=C2C(=C1)C(CCN[Si](C)(C)C)=CN2[Si](C)(C)C2141.6Semi standard non polar33892256
5-Methoxytryptamine,2TMS,isomer #1COC1=CC=C2C(=C1)C(CCN[Si](C)(C)C)=CN2[Si](C)(C)C2241.4Standard non polar33892256
5-Methoxytryptamine,2TMS,isomer #1COC1=CC=C2C(=C1)C(CCN[Si](C)(C)C)=CN2[Si](C)(C)C2437.9Standard polar33892256
5-Methoxytryptamine,2TMS,isomer #2COC1=CC=C2[NH]C=C(CCN([Si](C)(C)C)[Si](C)(C)C)C2=C12276.6Semi standard non polar33892256
5-Methoxytryptamine,2TMS,isomer #2COC1=CC=C2[NH]C=C(CCN([Si](C)(C)C)[Si](C)(C)C)C2=C12369.7Standard non polar33892256
5-Methoxytryptamine,2TMS,isomer #2COC1=CC=C2[NH]C=C(CCN([Si](C)(C)C)[Si](C)(C)C)C2=C12582.0Standard polar33892256
5-Methoxytryptamine,3TMS,isomer #1COC1=CC=C2C(=C1)C(CCN([Si](C)(C)C)[Si](C)(C)C)=CN2[Si](C)(C)C2361.1Semi standard non polar33892256
5-Methoxytryptamine,3TMS,isomer #1COC1=CC=C2C(=C1)C(CCN([Si](C)(C)C)[Si](C)(C)C)=CN2[Si](C)(C)C2438.0Standard non polar33892256
5-Methoxytryptamine,3TMS,isomer #1COC1=CC=C2C(=C1)C(CCN([Si](C)(C)C)[Si](C)(C)C)=CN2[Si](C)(C)C2401.3Standard polar33892256
5-Methoxytryptamine,1TBDMS,isomer #1COC1=CC=C2[NH]C=C(CCN[Si](C)(C)C(C)(C)C)C2=C12382.1Semi standard non polar33892256
5-Methoxytryptamine,1TBDMS,isomer #1COC1=CC=C2[NH]C=C(CCN[Si](C)(C)C(C)(C)C)C2=C12371.7Standard non polar33892256
5-Methoxytryptamine,1TBDMS,isomer #1COC1=CC=C2[NH]C=C(CCN[Si](C)(C)C(C)(C)C)C2=C12742.5Standard polar33892256
5-Methoxytryptamine,1TBDMS,isomer #2COC1=CC=C2C(=C1)C(CCN)=CN2[Si](C)(C)C(C)(C)C2280.9Semi standard non polar33892256
5-Methoxytryptamine,1TBDMS,isomer #2COC1=CC=C2C(=C1)C(CCN)=CN2[Si](C)(C)C(C)(C)C2266.9Standard non polar33892256
5-Methoxytryptamine,1TBDMS,isomer #2COC1=CC=C2C(=C1)C(CCN)=CN2[Si](C)(C)C(C)(C)C2707.7Standard polar33892256
5-Methoxytryptamine,2TBDMS,isomer #1COC1=CC=C2C(=C1)C(CCN[Si](C)(C)C(C)(C)C)=CN2[Si](C)(C)C(C)(C)C2618.0Semi standard non polar33892256
5-Methoxytryptamine,2TBDMS,isomer #1COC1=CC=C2C(=C1)C(CCN[Si](C)(C)C(C)(C)C)=CN2[Si](C)(C)C(C)(C)C2628.5Standard non polar33892256
5-Methoxytryptamine,2TBDMS,isomer #1COC1=CC=C2C(=C1)C(CCN[Si](C)(C)C(C)(C)C)=CN2[Si](C)(C)C(C)(C)C2613.4Standard polar33892256
5-Methoxytryptamine,2TBDMS,isomer #2COC1=CC=C2[NH]C=C(CCN([Si](C)(C)C(C)(C)C)[Si](C)(C)C(C)(C)C)C2=C12733.4Semi standard non polar33892256
5-Methoxytryptamine,2TBDMS,isomer #2COC1=CC=C2[NH]C=C(CCN([Si](C)(C)C(C)(C)C)[Si](C)(C)C(C)(C)C)C2=C12747.1Standard non polar33892256
5-Methoxytryptamine,2TBDMS,isomer #2COC1=CC=C2[NH]C=C(CCN([Si](C)(C)C(C)(C)C)[Si](C)(C)C(C)(C)C)C2=C12696.8Standard polar33892256
5-Methoxytryptamine,3TBDMS,isomer #1COC1=CC=C2C(=C1)C(CCN([Si](C)(C)C(C)(C)C)[Si](C)(C)C(C)(C)C)=CN2[Si](C)(C)C(C)(C)C2985.7Semi standard non polar33892256
5-Methoxytryptamine,3TBDMS,isomer #1COC1=CC=C2C(=C1)C(CCN([Si](C)(C)C(C)(C)C)[Si](C)(C)C(C)(C)C)=CN2[Si](C)(C)C(C)(C)C2962.0Standard non polar33892256
5-Methoxytryptamine,3TBDMS,isomer #1COC1=CC=C2C(=C1)C(CCN([Si](C)(C)C(C)(C)C)[Si](C)(C)C(C)(C)C)=CN2[Si](C)(C)C(C)(C)C2673.7Standard polar33892256
Spectra

GC-MS Spectra

Spectrum TypeDescriptionSplash KeyDeposition DateSourceView
Experimental GC-MSGC-MS Spectrum - 5-Methoxytryptamine GC-MS (2 TMS)splash10-0ue9-1960000000-9d22140ff2b48f31db092014-06-16HMDB team, MONA, MassBankView Spectrum
Experimental GC-MSGC-MS Spectrum - 5-Methoxytryptamine GC-MS (2 TMS)splash10-00dr-3900000000-b121de7d00a3821234012014-06-16HMDB team, MONA, MassBankView Spectrum
Experimental GC-MSGC-MS Spectrum - 5-Methoxytryptamine GC-MS (Non-derivatized)splash10-0ue9-1960000000-9d22140ff2b48f31db092017-09-12HMDB team, MONA, MassBankView Spectrum
Experimental GC-MSGC-MS Spectrum - 5-Methoxytryptamine GC-MS (Non-derivatized)splash10-00dr-3900000000-b121de7d00a3821234012017-09-12HMDB team, MONA, MassBankView Spectrum
Experimental GC-MSGC-MS Spectrum - 5-Methoxytryptamine GC-EI-TOF (Non-derivatized)splash10-00dr-2900000000-a5fe7e3acae8eed474de2017-09-12HMDB team, MONA, MassBankView Spectrum
Experimental GC-MSGC-MS Spectrum - 5-Methoxytryptamine GC-EI-TOF (Non-derivatized)splash10-00di-2900000000-2b80fe48b74acca6bebf2017-09-12HMDB team, MONA, MassBankView Spectrum
Predicted GC-MSPredicted GC-MS Spectrum - 5-Methoxytryptamine GC-MS (Non-derivatized) - 70eV, Positivesplash10-001i-6900000000-c9d325a89238b38270a62017-09-01Wishart LabView Spectrum
Predicted GC-MSPredicted GC-MS Spectrum - 5-Methoxytryptamine GC-MS (Non-derivatized) - 70eV, PositiveNot Available2021-10-12Wishart LabView Spectrum

MS/MS Spectra

Spectrum TypeDescriptionSplash KeyDeposition DateSourceView
Experimental LC-MS/MSLC-MS/MS Spectrum - 5-Methoxytryptamine Quattro_QQQ 10V, Negative-QTOF (Annotated)splash10-00dr-0900000000-ac5e7141a1f9a408fc342012-07-25HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - 5-Methoxytryptamine Quattro_QQQ 25V, Negative-QTOF (Annotated)splash10-0006-0900000000-6e5b3b429a1bb70ffaf42012-07-25HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - 5-Methoxytryptamine Quattro_QQQ 40V, Negative-QTOF (Annotated)splash10-0006-0900000000-e60ae04a11b9e498a9662012-07-25HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - 5-Methoxytryptamine LC-ESI-QQ (API3000, Applied Biosystems) 10V, Negative-QTOFsplash10-000i-0900000000-54e5a7201f25456dcad82012-08-31HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - 5-Methoxytryptamine LC-ESI-QQ (API3000, Applied Biosystems) 20V, Negative-QTOFsplash10-00di-1900000000-293475115ff46b97099a2012-08-31HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - 5-Methoxytryptamine LC-ESI-QQ (API3000, Applied Biosystems) 30V, Negative-QTOFsplash10-0006-1900000000-66f8cb9c260ecf410ce12012-08-31HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - 5-Methoxytryptamine LC-ESI-QQ (API3000, Applied Biosystems) 40V, Negative-QTOFsplash10-0006-1900000000-a14a529194c5227e34f82012-08-31HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - 5-Methoxytryptamine LC-ESI-QQ (API3000, Applied Biosystems) 50V, Negative-QTOFsplash10-002f-0900000000-ad73b33b853950cd56892012-08-31HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - 5-Methoxytryptamine LC-ESI-QQ (API3000, Applied Biosystems) 10V, Positive-QTOFsplash10-00di-0900000000-c4f465460bde21d469be2012-08-31HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - 5-Methoxytryptamine LC-ESI-QQ (API3000, Applied Biosystems) 20V, Positive-QTOFsplash10-00di-0900000000-f1d40ff7aa6c88ecdfd52012-08-31HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - 5-Methoxytryptamine LC-ESI-QQ (API3000, Applied Biosystems) 30V, Positive-QTOFsplash10-05fr-0900000000-22d3b9e8cbdb136bcb642012-08-31HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - 5-Methoxytryptamine LC-ESI-QQ (API3000, Applied Biosystems) 40V, Positive-QTOFsplash10-001i-0900000000-74e1867f5b88bc53f6772012-08-31HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - 5-Methoxytryptamine LC-ESI-QQ (API3000, Applied Biosystems) 50V, Positive-QTOFsplash10-001i-0900000000-438c89f58ad3c00989592012-08-31HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - 5-Methoxytryptamine LC-ESI-QQ , negative-QTOFsplash10-000i-0900000000-54e5a7201f25456dcad82017-09-14HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - 5-Methoxytryptamine LC-ESI-QQ , negative-QTOFsplash10-00di-1900000000-adf7f816d92642625bdd2017-09-14HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - 5-Methoxytryptamine LC-ESI-QQ , negative-QTOFsplash10-0006-1900000000-66f8cb9c260ecf410ce12017-09-14HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - 5-Methoxytryptamine LC-ESI-QQ , negative-QTOFsplash10-0006-1900000000-a14a529194c5227e34f82017-09-14HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - 5-Methoxytryptamine LC-ESI-QQ , negative-QTOFsplash10-002f-0900000000-ad73b33b853950cd56892017-09-14HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - 5-Methoxytryptamine Linear Ion Trap , negative-QTOFsplash10-00di-0900000000-485d7582e65bfa3e31f12017-09-14HMDB team, MONAView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 5-Methoxytryptamine 10V, Positive-QTOFsplash10-006x-0900000000-f95e78148902f5d5fd5c2017-09-01Wishart LabView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 5-Methoxytryptamine 20V, Positive-QTOFsplash10-00di-0900000000-df05e0b6cdfd7405bd612017-09-01Wishart LabView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 5-Methoxytryptamine 40V, Positive-QTOFsplash10-0006-1900000000-29075396a509857c49cf2017-09-01Wishart LabView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 5-Methoxytryptamine 10V, Negative-QTOFsplash10-000i-0900000000-d54a34cc910e2e660e8f2017-09-01Wishart LabView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 5-Methoxytryptamine 20V, Negative-QTOFsplash10-000i-0900000000-7444dab440e6fbc176f12017-09-01Wishart LabView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 5-Methoxytryptamine 40V, Negative-QTOFsplash10-001i-0900000000-e4e316fc6ae64a01da7f2017-09-01Wishart LabView Spectrum

NMR Spectra

Spectrum TypeDescriptionDeposition DateSourceView
Experimental 2D NMR[1H, 13C]-HSQC NMR Spectrum (2D, 600 MHz, H2O, experimental)2012-12-05Wishart LabView Spectrum
Biological Properties
Cellular LocationsNot Available
Biospecimen Locations
  • Urine
Tissue Locations
  • Platelet
  • Thyroid Gland
Pathways
Normal Concentrations
BiospecimenStatusValueAgeSexConditionReferenceDetails
UrineDetected and Quantified0.0016 (0.0-0.0032) umol/mmol creatinineAdult (>18 years old)BothNormal
    • Geigy Scientific ...
    • West Cadwell, N.J...
    • Basel, Switzerlan...
details
Abnormal Concentrations
Not Available
Associated Disorders and Diseases
Disease ReferencesNone
Associated OMIM IDsNone
DrugBank IDNot Available
Phenol Explorer Compound IDNot Available
FooDB IDFDB023311
KNApSAcK IDNot Available
Chemspider ID1767
KEGG Compound IDC05659
BioCyc IDCPD-12018
BiGG IDNot Available
Wikipedia Link5-Methoxytryptamine
METLIN ID7015
PubChem Compound1833
PDB IDNot Available
ChEBI ID2089
Food Biomarker OntologyNot Available
VMH IDNot Available
MarkerDB IDNot Available
Good Scents IDNot Available
References
Synthesis ReferenceSzmuszkovicz, J.; Anthony, W. C.; Heinzelman, R. V. N-Acetyl-5-methoxytryptamine. Journal of Organic Chemistry (1960), 25 857-9.
Material Safety Data Sheet (MSDS)Download (PDF)
General References
  1. Geffard M, Dulluc J, Rock AM: Antisera against the indolealkylamines: tryptophan, 5-hydroxytryptophan, 5-hydroxytryptamine, 5-methoxytryptophan, and 5-methoxytryptamine tested by an enzyme-linked immunosorbent assay method. J Neurochem. 1985 Apr;44(4):1221-8. [PubMed:3919158 ]
  2. Rom-Bugolavskaia ES, Shcherbakova VS, Komarova IV: [The effect of melatonin and mexamine on the human thyroid under in-vitro conditions]. Eksp Klin Farmakol. 1997 Jul-Aug;60(4):46-9. [PubMed:9376758 ]
  3. Kirchheiner J, Henckel HB, Franke L, Meineke I, Tzvetkov M, Uebelhack R, Roots I, Brockmoller J: Impact of the CYP2D6 ultra-rapid metabolizer genotype on doxepin pharmacokinetics and serotonin in platelets. Pharmacogenet Genomics. 2005 Aug;15(8):579-87. [PubMed:16007002 ]
  4. Romsing S, Bokman F, Bergqvist Y: Determination of melatonin in saliva using automated solid-phase extraction, high-performance liquid chromatography and fluorescence detection. Scand J Clin Lab Invest. 2006;66(3):181-90. [PubMed:16714247 ]

Enzymes

General function:
Involved in N-acetyltransferase activity
Specific function:
Controls the night/day rhythm of melatonin production in the pineal gland. Catalyzes the N-acetylation of serotonin into N-acetylserotonin, the penultimate step in the synthesis of melatonin.
Gene Name:
AANAT
Uniprot ID:
Q16613
Molecular weight:
23343.8
General function:
Involved in oxidoreductase activity
Specific function:
Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOA preferentially oxidizes biogenic amines such as 5-hydroxytryptamine (5-HT), norepinephrine and epinephrine.
Gene Name:
MAOA
Uniprot ID:
P21397
Molecular weight:
59681.27
General function:
Involved in protein methyltransferase activity
Specific function:
Methylates (mono and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in some proteins
Gene Name:
PRMT3
Uniprot ID:
O60678
Molecular weight:
59902.7
General function:
Not Available
Specific function:
N5-glutamine methyltransferase responsible for the methylation of the GGQ triplet of the mitochondrial translation release factor MTRF1L.
Gene Name:
HEMK1
Uniprot ID:
Q9Y5R4
Molecular weight:
Not Available
Reactions
Serotonin + 5-Methyltetrahydrofolic acid → 5-Methoxytryptamine + Tetrahydrofolic aciddetails
General function:
Not Available
Specific function:
Probable methyltransferase (By similarity).
Gene Name:
METTL2B
Uniprot ID:
Q6P1Q9
Molecular weight:
Not Available
Reactions
Serotonin + 5-Methyltetrahydrofolic acid → 5-Methoxytryptamine + Tetrahydrofolic aciddetails
General function:
Not Available
Specific function:
Probable methyltransferase (By similarity).
Gene Name:
METTL6
Uniprot ID:
Q8TCB7
Molecular weight:
Not Available
Reactions
Serotonin + 5-Methyltetrahydrofolic acid → 5-Methoxytryptamine + Tetrahydrofolic aciddetails
General function:
Not Available
Specific function:
Methyltransferase that may act on DNA.
Gene Name:
WBSCR22
Uniprot ID:
O43709
Molecular weight:
Not Available
Reactions
Serotonin + 5-Methyltetrahydrofolic acid → 5-Methoxytryptamine + Tetrahydrofolic aciddetails