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Record Information
Version5.0
StatusDetected and Quantified
Creation Date2009-01-30 10:07:36 UTC
Update Date2022-03-07 02:51:12 UTC
HMDB IDHMDB0011628
Secondary Accession Numbers
  • HMDB11628
Metabolite Identification
Common NameGlycyrrhetinic acid
DescriptionGlycyrrhetinic acid is a pentacyclic triterpenoid derivative of the beta-amyrin type obtained from the hydrolysis of glycyrrhizic acid, which was first obtained from the herb liquorice. It is used in flavouring and it masks the bitter taste of drugs like aloe and quinine. It is effective in the treatment of peptic ulcer and also has expectorant (antitussive) properties (PMID:32106571 ). In glycyrrhetinic acid the functional group (R) is a hydroxyl group. Research in 2005 demonstrated that with a proper functional group a very effective glycyrrhetinic artificial sweetener can be obtained. When R is an anionic NHCO(CH2)CO2K side chain, the sweetening effect is found to 1200 times that of sugar (human sensory panel data). A shorter or longer spacer reduces the sweetening effect. One explanation is that the taste bud cell receptor has 1.3 nanometers (13 angstroms) available for docking with the sweetener molecule. In addition the sweetener molecule requires three proton donor positions of which two reside at the extremities to be able to interact efficiently with the receptor cavity.
Structure
Data?1582752931
Synonyms
ValueSource
GlycyrrhetinateGenerator
18b-Glycyrrhetic acidHMDB
18b-Glycyrrhetinic acidHMDB
18b-Glycyrrhtinic acidHMDB
3-Glycyrrhetinic acidHMDB
3-Hydroxy-11-oxoolean-12-en-29-OateHMDB
3-Hydroxy-11-oxoolean-12-en-29-Oic acidHMDB
3-Hydroxy-11-oxoolean-12-en-29-Oic acid (acd/name 4.0)HMDB
3b-Hydroxy-11-oxo-olean-12-en-30-OateHMDB
3b-Hydroxy-11-oxo-olean-12-en-30-Oic acidHMDB
3b-Hydroxy-11-oxoolean-12-en-30-OateHMDB
3b-Hydroxy-11-oxoolean-12-en-30-Oic acidHMDB
a-Glycyrrhetinic acidHMDB
alpha-Glycyrrhetinic acidHMDB
b-Glycyrrhetic acidHMDB
beta-Glycyrrhetic acidHMDB
BiosoneHMDB
EnoxoloneHMDB
Glycyrrhetic acidHMDB
GlycyrrhetinHMDB
Uralenic acidHMDB
Acid, glycyrrhetinicHMDB
Dexo brand OF glycyrrhetinic acidHMDB
Po 12HMDB
Rhetinic acidHMDB
Acid, glycyrrheticHMDB
Plantes et médecines brand OF glycyrrhetinic acidHMDB
Acid, rhetinicHMDB
Acid, uralenicHMDB
ArthrodontHMDB
GlyciramHMDB
GlycyramHMDB
JintanHMDB
(2S,4AS,6as,6BR,10S,12as)-10-hydroxy-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-2-carboxylateHMDB
12, PoHMDB
Glycyrrhetinic acidHMDB, MeSH
Chemical FormulaC30H46O4
Average Molecular Weight470.6838
Monoisotopic Molecular Weight470.33960996
IUPAC Name(2S,4aS,6aS,6bR,10S,12aS)-10-hydroxy-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-2-carboxylic acid
Traditional Name(2S,4aS,6aS,6bR,10S,12aS)-10-hydroxy-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-3,4,5,6,7,8,8a,10,11,12,12b,14b-dodecahydro-1H-picene-2-carboxylic acid
CAS Registry Number471-53-4
SMILES
CC1(C)[C@@H](O)CC[C@@]2(C)C1CC[C@]1(C)C2C(=O)C=C2C3C[C@](C)(CC[C@]3(C)CC[C@@]12C)C(O)=O
InChI Identifier
InChI=1S/C30H46O4/c1-25(2)21-8-11-30(7)23(28(21,5)10-9-22(25)32)20(31)16-18-19-17-27(4,24(33)34)13-12-26(19,3)14-15-29(18,30)6/h16,19,21-23,32H,8-15,17H2,1-7H3,(H,33,34)/t19?,21?,22-,23?,26+,27-,28-,29+,30+/m0/s1
InChI KeyMPDGHEJMBKOTSU-WFJWTYAKSA-N
Chemical Taxonomy
Description Belongs to the class of organic compounds known as triterpenoids. These are terpene molecules containing six isoprene units.
KingdomOrganic compounds
Super ClassLipids and lipid-like molecules
ClassPrenol lipids
Sub ClassTriterpenoids
Direct ParentTriterpenoids
Alternative Parents
Substituents
  • Triterpenoid
  • Cyclohexenone
  • Cyclic alcohol
  • Secondary alcohol
  • Ketone
  • Monocarboxylic acid or derivatives
  • Carboxylic acid
  • Carboxylic acid derivative
  • Organic oxygen compound
  • Organic oxide
  • Hydrocarbon derivative
  • Organooxygen compound
  • Carbonyl group
  • Alcohol
  • Aliphatic homopolycyclic compound
Molecular FrameworkAliphatic homopolycyclic compounds
External DescriptorsNot Available
Ontology
Physiological effectNot Available
Disposition
ProcessNot Available
RoleNot Available
Physical Properties
StateSolid
Experimental Molecular Properties
PropertyValueReference
Melting Point296 °CNot Available
Boiling PointNot AvailableNot Available
Water SolubilityNot AvailableNot Available
LogPNot AvailableNot Available
Experimental Chromatographic PropertiesNot Available
Predicted Molecular Properties
PropertyValueSource
Water Solubility0.0017 g/LALOGPS
logP5.45ALOGPS
logP6.03ChemAxon
logS-5.4ALOGPS
pKa (Strongest Acidic)4.44ChemAxon
pKa (Strongest Basic)-0.84ChemAxon
Physiological Charge-1ChemAxon
Hydrogen Acceptor Count4ChemAxon
Hydrogen Donor Count2ChemAxon
Polar Surface Area74.6 ŲChemAxon
Rotatable Bond Count1ChemAxon
Refractivity134.27 m³·mol⁻¹ChemAxon
Polarizability55.39 ųChemAxon
Number of Rings5ChemAxon
BioavailabilityYesChemAxon
Rule of FiveNoChemAxon
Ghose FilterNoChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleNoChemAxon
Predicted Chromatographic Properties

Predicted Collision Cross Sections

PredictorAdduct TypeCCS Value (Å2)Reference
DarkChem[M+H]+213.51531661259
DarkChem[M-H]-203.10131661259
DeepCCS[M-2H]-248.6430932474
DeepCCS[M+Na]+223.22330932474
AllCCS[M+H]+217.232859911
AllCCS[M+H-H2O]+215.632859911
AllCCS[M+NH4]+218.732859911
AllCCS[M+Na]+219.132859911
AllCCS[M-H]-213.732859911
AllCCS[M+Na-2H]-215.732859911
AllCCS[M+HCOO]-218.132859911

Predicted Kovats Retention Indices

Underivatized

MetaboliteSMILESKovats RI ValueColumn TypeReference
Glycyrrhetinic acidCC1(C)[C@@H](O)CC[C@@]2(C)C1CC[C@]1(C)C2C(=O)C=C2C3C[C@](C)(CC[C@]3(C)CC[C@@]12C)C(O)=O3768.1Standard polar33892256
Glycyrrhetinic acidCC1(C)[C@@H](O)CC[C@@]2(C)C1CC[C@]1(C)C2C(=O)C=C2C3C[C@](C)(CC[C@]3(C)CC[C@@]12C)C(O)=O3512.6Standard non polar33892256
Glycyrrhetinic acidCC1(C)[C@@H](O)CC[C@@]2(C)C1CC[C@]1(C)C2C(=O)C=C2C3C[C@](C)(CC[C@]3(C)CC[C@@]12C)C(O)=O3950.7Semi standard non polar33892256

Derivatized

Derivative Name / StructureSMILESKovats RI ValueColumn TypeReference
Glycyrrhetinic acid,1TMS,isomer #1CC1(C)C2CC[C@]3(C)C(C(=O)C=C4C5C[C@@](C)(C(=O)O)CC[C@]5(C)CC[C@]43C)[C@@]2(C)CC[C@@H]1O[Si](C)(C)C4017.4Semi standard non polar33892256
Glycyrrhetinic acid,1TMS,isomer #2CC1(C)C2CC[C@]3(C)C(C(=O)C=C4C5C[C@@](C)(C(=O)O[Si](C)(C)C)CC[C@]5(C)CC[C@]43C)[C@@]2(C)CC[C@@H]1O3943.4Semi standard non polar33892256
Glycyrrhetinic acid,1TMS,isomer #3CC1(C)C2CC[C@]3(C)C(=C(O[Si](C)(C)C)C=C4C5C[C@@](C)(C(=O)O)CC[C@]5(C)CC[C@]43C)[C@@]2(C)CC[C@@H]1O3943.9Semi standard non polar33892256
Glycyrrhetinic acid,2TMS,isomer #1CC1(C)C2CC[C@]3(C)C(C(=O)C=C4C5C[C@@](C)(C(=O)O[Si](C)(C)C)CC[C@]5(C)CC[C@]43C)[C@@]2(C)CC[C@@H]1O[Si](C)(C)C3933.4Semi standard non polar33892256
Glycyrrhetinic acid,2TMS,isomer #2CC1(C)C2CC[C@]3(C)C(=C(O[Si](C)(C)C)C=C4C5C[C@@](C)(C(=O)O)CC[C@]5(C)CC[C@]43C)[C@@]2(C)CC[C@@H]1O[Si](C)(C)C3919.0Semi standard non polar33892256
Glycyrrhetinic acid,2TMS,isomer #3CC1(C)C2CC[C@]3(C)C(=C(O[Si](C)(C)C)C=C4C5C[C@@](C)(C(=O)O[Si](C)(C)C)CC[C@]5(C)CC[C@]43C)[C@@]2(C)CC[C@@H]1O3876.6Semi standard non polar33892256
Glycyrrhetinic acid,3TMS,isomer #1CC1(C)C2CC[C@]3(C)C(=C(O[Si](C)(C)C)C=C4C5C[C@@](C)(C(=O)O[Si](C)(C)C)CC[C@]5(C)CC[C@]43C)[C@@]2(C)CC[C@@H]1O[Si](C)(C)C3823.9Semi standard non polar33892256
Glycyrrhetinic acid,3TMS,isomer #1CC1(C)C2CC[C@]3(C)C(=C(O[Si](C)(C)C)C=C4C5C[C@@](C)(C(=O)O[Si](C)(C)C)CC[C@]5(C)CC[C@]43C)[C@@]2(C)CC[C@@H]1O[Si](C)(C)C3712.5Standard non polar33892256
Glycyrrhetinic acid,3TMS,isomer #1CC1(C)C2CC[C@]3(C)C(=C(O[Si](C)(C)C)C=C4C5C[C@@](C)(C(=O)O[Si](C)(C)C)CC[C@]5(C)CC[C@]43C)[C@@]2(C)CC[C@@H]1O[Si](C)(C)C3841.5Standard polar33892256
Glycyrrhetinic acid,1TBDMS,isomer #1CC1(C)C2CC[C@]3(C)C(C(=O)C=C4C5C[C@@](C)(C(=O)O)CC[C@]5(C)CC[C@]43C)[C@@]2(C)CC[C@@H]1O[Si](C)(C)C(C)(C)C4208.3Semi standard non polar33892256
Glycyrrhetinic acid,1TBDMS,isomer #2CC1(C)C2CC[C@]3(C)C(C(=O)C=C4C5C[C@@](C)(C(=O)O[Si](C)(C)C(C)(C)C)CC[C@]5(C)CC[C@]43C)[C@@]2(C)CC[C@@H]1O4175.5Semi standard non polar33892256
Glycyrrhetinic acid,1TBDMS,isomer #3CC1(C)C2CC[C@]3(C)C(=C(O[Si](C)(C)C(C)(C)C)C=C4C5C[C@@](C)(C(=O)O)CC[C@]5(C)CC[C@]43C)[C@@]2(C)CC[C@@H]1O4161.5Semi standard non polar33892256
Glycyrrhetinic acid,2TBDMS,isomer #1CC1(C)C2CC[C@]3(C)C(C(=O)C=C4C5C[C@@](C)(C(=O)O[Si](C)(C)C(C)(C)C)CC[C@]5(C)CC[C@]43C)[C@@]2(C)CC[C@@H]1O[Si](C)(C)C(C)(C)C4367.1Semi standard non polar33892256
Glycyrrhetinic acid,2TBDMS,isomer #2CC1(C)C2CC[C@]3(C)C(=C(O[Si](C)(C)C(C)(C)C)C=C4C5C[C@@](C)(C(=O)O)CC[C@]5(C)CC[C@]43C)[C@@]2(C)CC[C@@H]1O[Si](C)(C)C(C)(C)C4324.0Semi standard non polar33892256
Glycyrrhetinic acid,2TBDMS,isomer #3CC1(C)C2CC[C@]3(C)C(=C(O[Si](C)(C)C(C)(C)C)C=C4C5C[C@@](C)(C(=O)O[Si](C)(C)C(C)(C)C)CC[C@]5(C)CC[C@]43C)[C@@]2(C)CC[C@@H]1O4322.4Semi standard non polar33892256
Glycyrrhetinic acid,3TBDMS,isomer #1CC1(C)C2CC[C@]3(C)C(=C(O[Si](C)(C)C(C)(C)C)C=C4C5C[C@@](C)(C(=O)O[Si](C)(C)C(C)(C)C)CC[C@]5(C)CC[C@]43C)[C@@]2(C)CC[C@@H]1O[Si](C)(C)C(C)(C)C4435.3Semi standard non polar33892256
Glycyrrhetinic acid,3TBDMS,isomer #1CC1(C)C2CC[C@]3(C)C(=C(O[Si](C)(C)C(C)(C)C)C=C4C5C[C@@](C)(C(=O)O[Si](C)(C)C(C)(C)C)CC[C@]5(C)CC[C@]43C)[C@@]2(C)CC[C@@H]1O[Si](C)(C)C(C)(C)C4428.0Standard non polar33892256
Glycyrrhetinic acid,3TBDMS,isomer #1CC1(C)C2CC[C@]3(C)C(=C(O[Si](C)(C)C(C)(C)C)C=C4C5C[C@@](C)(C(=O)O[Si](C)(C)C(C)(C)C)CC[C@]5(C)CC[C@]43C)[C@@]2(C)CC[C@@H]1O[Si](C)(C)C(C)(C)C4085.4Standard polar33892256
Spectra

GC-MS Spectra

Spectrum TypeDescriptionSplash KeyDeposition DateSourceView
Predicted GC-MSPredicted GC-MS Spectrum - Glycyrrhetinic acid GC-MS (Non-derivatized) - 70eV, Positivesplash10-0a4l-0217900000-aadc516f5cfd224a8c712017-09-01Wishart LabView Spectrum
Predicted GC-MSPredicted GC-MS Spectrum - Glycyrrhetinic acid GC-MS (2 TMS) - 70eV, Positivesplash10-0f6t-0000192000-c460e8d231076de78a052017-10-06Wishart LabView Spectrum
Predicted GC-MSPredicted GC-MS Spectrum - Glycyrrhetinic acid GC-MS (Non-derivatized) - 70eV, PositiveNot Available2021-10-12Wishart LabView Spectrum

MS/MS Spectra

Spectrum TypeDescriptionSplash KeyDeposition DateSourceView
Experimental LC-MS/MSLC-MS/MS Spectrum - Glycyrrhetinic acid ESI-TOF 10V, Negative-QTOFsplash10-0a4i-0000930000-25139768b4507e334b4a2018-05-25HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Glycyrrhetinic acid ESI-TOF 20V, Negative-QTOFsplash10-0a4i-0000930000-25139768b4507e334b4a2018-05-25HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Glycyrrhetinic acid ESI-TOF 50V, Negative-QTOFsplash10-00or-0000900000-ada4fdd603d1852beae82018-05-25HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Glycyrrhetinic acid ESI-TOF 40V, Negative-QTOFsplash10-014i-0000900000-276dcd237f3df1b55bf72018-05-25HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Glycyrrhetinic acid ESI-TOF , Negative-QTOFsplash10-014i-0000911000-952bbb171fba142dba692018-05-25HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Glycyrrhetinic acid ESI-TOF 10V, Negative-QTOFsplash10-014u-0000700009-50048523dd30a3c691262018-05-25HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Glycyrrhetinic acid ESI-TOF 30V, Negative-QTOFsplash10-014u-0000700009-50048523dd30a3c691262018-05-25HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Glycyrrhetinic acid ESI-TOF 10V, Negative-QTOFsplash10-014i-0000900000-125f02720b2a01ba256e2018-05-25HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Glycyrrhetinic acid ESI-TOF 20V, Negative-QTOFsplash10-014i-0000900000-6466c540accc2a7ad3802018-05-25HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Glycyrrhetinic acid ESI-TOF 50V, Negative-QTOFsplash10-00or-0000900000-ada4fdd603d1852beae82018-05-25HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Glycyrrhetinic acid ESI-TOF 40V, Negative-QTOFsplash10-014i-0000900000-276dcd237f3df1b55bf72018-05-25HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Glycyrrhetinic acid ESI-TOF , Negative-QTOFsplash10-014i-0000911000-952bbb171fba142dba692018-05-25HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Glycyrrhetinic acid ESI-TOF 10V, Negative-QTOFsplash10-014u-0000700009-50048523dd30a3c691262018-05-25HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Glycyrrhetinic acid ESI-TOF 30V, Negative-QTOFsplash10-014i-0000900000-c50958d1a751bbfbca792018-05-25HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Glycyrrhetinic acid LC-ESI-QFT , negative-QTOFsplash10-014i-0000900000-027d29bdfec0cb682eab2018-05-25HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Glycyrrhetinic acid LC-ESI-QFT , negative-QTOFsplash10-014i-0000900000-7d4a004adc92eda079052018-05-25HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Glycyrrhetinic acid LC-ESI-QFT , negative-QTOFsplash10-014i-0000900000-04e795c32f4f79f139f32018-05-25HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Glycyrrhetinic acid LC-ESI-QFT , negative-QTOFsplash10-0a6r-0004900000-5d9468128c8fc0642c7d2018-05-25HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Glycyrrhetinic acid LC-ESI-QFT , negative-QTOFsplash10-0a4i-0009200000-c23de15fecaedafae33d2018-05-25HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Glycyrrhetinic acid LC-ESI-QFT , negative-QTOFsplash10-056r-0109000000-1bd1687c967adde80ff92018-05-25HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Glycyrrhetinic acid LC-ESI-QFT , negative-QTOFsplash10-00di-0921000000-be6ecff38e178ed81d852018-05-25HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Glycyrrhetinic acid LC-ESI-QFT , negative-QTOFsplash10-00di-0900000000-b5252030bb373e0bea682018-05-25HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Glycyrrhetinic acid LC-ESI-QFT , negative-QTOFsplash10-00di-0900000000-81872dd2517f0319e2d52018-05-25HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Glycyrrhetinic acid LC-ESI-QQ , negative-QTOFsplash10-014i-0000900000-84865ea36583c793b08e2018-05-25HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Glycyrrhetinic acid LC-ESI-QQ , negative-QTOFsplash10-014i-0000900000-eced6d2a003b7f1e7f252018-05-25HMDB team, MONAView Spectrum

NMR Spectra

Spectrum TypeDescriptionDeposition DateSourceView
Experimental 2D NMR[1H, 13C]-HSQC NMR Spectrum (2D, 600 MHz, 100%_DMSO, experimental)2012-12-05Wishart LabView Spectrum
Biological Properties
Cellular Locations
  • Extracellular
  • Membrane
Biospecimen Locations
  • Blood
Tissue LocationsNot Available
Pathways
Normal Concentrations
BiospecimenStatusValueAgeSexConditionReferenceDetails
BloodDetected and Quantified0.104 +/- 0.008 uMAdult (>18 years old)BothNormal details
Abnormal Concentrations
Not Available
Associated Disorders and Diseases
Disease ReferencesNone
Associated OMIM IDsNone
DrugBank IDNot Available
Phenol Explorer Compound IDNot Available
FooDB IDFDB020713
KNApSAcK IDC00003521
Chemspider ID17930566
KEGG Compound IDC02283
BioCyc IDNot Available
BiGG IDNot Available
Wikipedia LinkEnoxolone
METLIN IDNot Available
PubChem Compound18526330
PDB IDNot Available
ChEBI ID30853
Food Biomarker OntologyNot Available
VMH IDNot Available
MarkerDB IDNot Available
Good Scents IDNot Available
References
Synthesis ReferenceNot Available
Material Safety Data Sheet (MSDS)Download (PDF)
General References
  1. Simons K, Toomre D: Lipid rafts and signal transduction. Nat Rev Mol Cell Biol. 2000 Oct;1(1):31-9. [PubMed:11413487 ]
  2. Watson AD: Thematic review series: systems biology approaches to metabolic and cardiovascular disorders. Lipidomics: a global approach to lipid analysis in biological systems. J Lipid Res. 2006 Oct;47(10):2101-11. Epub 2006 Aug 10. [PubMed:16902246 ]
  3. Sethi JK, Vidal-Puig AJ: Thematic review series: adipocyte biology. Adipose tissue function and plasticity orchestrate nutritional adaptation. J Lipid Res. 2007 Jun;48(6):1253-62. Epub 2007 Mar 20. [PubMed:17374880 ]
  4. Lingwood D, Simons K: Lipid rafts as a membrane-organizing principle. Science. 2010 Jan 1;327(5961):46-50. doi: 10.1126/science.1174621. [PubMed:20044567 ]
  5. El-Saber Batiha G, Magdy Beshbishy A, El-Mleeh A, Abdel-Daim MM, Prasad Devkota H: Traditional Uses, Bioactive Chemical Constituents, and Pharmacological and Toxicological Activities of Glycyrrhiza glabra L. (Fabaceae). Biomolecules. 2020 Feb 25;10(3). pii: biom10030352. doi: 10.3390/biom10030352. [PubMed:32106571 ]
  6. Gunstone, Frank D., John L. Harwood, and Albert J. Dijkstra (2007). The lipid handbook with CD-ROM. CRC Press.

Enzymes

General function:
Involved in oxidoreductase activity
Specific function:
Catalyzes the conversion of cortisol to the inactive metabolite cortisone. Modulates intracellular glucocorticoid levels, thus protecting the nonselective mineralocorticoid receptor from occupation by glucocorticoids.
Gene Name:
HSD11B2
Uniprot ID:
P80365
Molecular weight:
44126.06