Record Information |
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Version | 5.0 |
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Status | Expected but not Quantified |
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Creation Date | 2012-09-06 15:16:49 UTC |
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Update Date | 2022-03-07 02:51:36 UTC |
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HMDB ID | HMDB0014398 |
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Secondary Accession Numbers | |
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Metabolite Identification |
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Common Name | Medrysone |
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Description | Medrysone is only found in individuals that have used or taken this drug. It is a corticosteroid used in ophthalmology. [Wikipedia ]There is no generally accepted explanation for the mechanism of action of ocular corticosteroids. However, corticosteroids are thought to act by the induction of phospholipase A2 inhibitory proteins, collectively called lipocortins. It is postulated that these proteins control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes by inhibiting the release of their common precursor, arachidonic acid. Arachidonic acid is released from membrane phospholipids by phospholipase A2. Initially, the drug binds to the glucocorticoid receptor in the cytosol. This migrates to the nucleus and binds to genetic elements which cause activation and repression of the involved genes in the inflammatory pathway. |
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Structure | [H][C@@]12CC[C@H](C(C)=O)[C@@]1(C)C[C@H](O)[C@@]1([H])[C@@]2([H])C[C@H](C)C2=CC(=O)CC[C@]12C InChI=1S/C22H32O3/c1-12-9-15-17-6-5-16(13(2)23)22(17,4)11-19(25)20(15)21(3)8-7-14(24)10-18(12)21/h10,12,15-17,19-20,25H,5-9,11H2,1-4H3/t12-,15-,16+,17-,19-,20+,21-,22+/m0/s1 |
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Synonyms | Value | Source |
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11beta-Hydroxy-6alpha-methylpregn-4-ene-3,20-dione | Kegg | HMS | Kegg | 11b-Hydroxy-6a-methylpregn-4-ene-3,20-dione | Generator | 11Β-hydroxy-6α-methylpregn-4-ene-3,20-dione | Generator | Hydroxymesterone | HMDB | 11-Hydroxy-6-methylprogesterone | HMDB | HMS Liquifilm | HMDB | HMS Suspension | HMDB |
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Chemical Formula | C22H32O3 |
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Average Molecular Weight | 344.4877 |
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Monoisotopic Molecular Weight | 344.23514489 |
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IUPAC Name | (1S,2R,8S,10S,11S,14S,15S,17S)-14-acetyl-17-hydroxy-2,8,15-trimethyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadec-6-en-5-one |
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Traditional Name | medrysone |
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CAS Registry Number | 2668-66-8 |
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SMILES | [H][C@@]12CC[C@H](C(C)=O)[C@@]1(C)C[C@H](O)[C@@]1([H])[C@@]2([H])C[C@H](C)C2=CC(=O)CC[C@]12C |
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InChI Identifier | InChI=1S/C22H32O3/c1-12-9-15-17-6-5-16(13(2)23)22(17,4)11-19(25)20(15)21(3)8-7-14(24)10-18(12)21/h10,12,15-17,19-20,25H,5-9,11H2,1-4H3/t12-,15-,16+,17-,19-,20+,21-,22+/m0/s1 |
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InChI Key | GZENKSODFLBBHQ-ILSZZQPISA-N |
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Chemical Taxonomy |
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Description | Belongs to the class of organic compounds known as gluco/mineralocorticoids, progestogins and derivatives. These are steroids with a structure based on a hydroxylated prostane moiety. |
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Kingdom | Organic compounds |
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Super Class | Lipids and lipid-like molecules |
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Class | Steroids and steroid derivatives |
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Sub Class | Pregnane steroids |
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Direct Parent | Gluco/mineralocorticoids, progestogins and derivatives |
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Alternative Parents | |
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Substituents | - Progestogin-skeleton
- 20-oxosteroid
- 3-oxo-delta-4-steroid
- 3-oxosteroid
- 11-hydroxysteroid
- 11-beta-hydroxysteroid
- Hydroxysteroid
- Oxosteroid
- Delta-4-steroid
- Cyclohexenone
- Cyclic alcohol
- Ketone
- Secondary alcohol
- Cyclic ketone
- Hydrocarbon derivative
- Organic oxygen compound
- Carbonyl group
- Alcohol
- Organic oxide
- Organooxygen compound
- Aliphatic homopolycyclic compound
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Molecular Framework | Aliphatic homopolycyclic compounds |
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External Descriptors | |
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Ontology |
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Physiological effect | Not Available |
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Disposition | |
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Process | Not Available |
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Role | Not Available |
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Physical Properties |
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State | Solid |
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Experimental Molecular Properties | Property | Value | Reference |
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Melting Point | 156.5 °C | Not Available | Boiling Point | Not Available | Not Available | Water Solubility | 0.034 g/L | Not Available | LogP | 3.2 | Not Available |
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Experimental Chromatographic Properties | Experimental Collision Cross Sections |
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Predicted Molecular Properties | | Show more...
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Predicted Chromatographic Properties | Predicted Collision Cross SectionsPredicted Kovats Retention IndicesUnderivatizedDerivatizedDerivative Name / Structure | SMILES | Kovats RI Value | Column Type | Reference |
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Medrysone,1TMS,isomer #1 | CC(=O)[C@H]1CC[C@H]2[C@@H]3C[C@H](C)C4=CC(=O)CC[C@]4(C)[C@H]3[C@@H](O[Si](C)(C)C)C[C@]12C | 2931.9 | Semi standard non polar | 33892256 | Medrysone,1TMS,isomer #2 | CC(O[Si](C)(C)C)=C1CC[C@H]2[C@@H]3C[C@H](C)C4=CC(=O)CC[C@]4(C)[C@H]3[C@@H](O)C[C@]12C | 3058.8 | Semi standard non polar | 33892256 | Medrysone,1TMS,isomer #3 | CC(=O)[C@H]1CC[C@H]2[C@@H]3C[C@H](C)C4=CC(O[Si](C)(C)C)=CC[C@]4(C)[C@H]3[C@@H](O)C[C@]12C | 2939.6 | Semi standard non polar | 33892256 | Medrysone,1TMS,isomer #4 | C=C(O[Si](C)(C)C)[C@H]1CC[C@H]2[C@@H]3C[C@H](C)C4=CC(=O)CC[C@]4(C)[C@H]3[C@@H](O)C[C@]12C | 3017.5 | Semi standard non polar | 33892256 | Medrysone,2TMS,isomer #1 | CC(O[Si](C)(C)C)=C1CC[C@H]2[C@@H]3C[C@H](C)C4=CC(=O)CC[C@]4(C)[C@H]3[C@@H](O[Si](C)(C)C)C[C@]12C | 2926.2 | Semi standard non polar | 33892256 | Medrysone,2TMS,isomer #1 | CC(O[Si](C)(C)C)=C1CC[C@H]2[C@@H]3C[C@H](C)C4=CC(=O)CC[C@]4(C)[C@H]3[C@@H](O[Si](C)(C)C)C[C@]12C | 2906.9 | Standard non polar | 33892256 | Medrysone,2TMS,isomer #1 | CC(O[Si](C)(C)C)=C1CC[C@H]2[C@@H]3C[C@H](C)C4=CC(=O)CC[C@]4(C)[C@H]3[C@@H](O[Si](C)(C)C)C[C@]12C | 3261.6 | Standard polar | 33892256 | Medrysone,2TMS,isomer #2 | CC(=O)[C@H]1CC[C@H]2[C@@H]3C[C@H](C)C4=CC(O[Si](C)(C)C)=CC[C@]4(C)[C@H]3[C@@H](O[Si](C)(C)C)C[C@]12C | 2819.4 | Semi standard non polar | 33892256 | Medrysone,2TMS,isomer #2 | CC(=O)[C@H]1CC[C@H]2[C@@H]3C[C@H](C)C4=CC(O[Si](C)(C)C)=CC[C@]4(C)[C@H]3[C@@H](O[Si](C)(C)C)C[C@]12C | 2887.8 | Standard non polar | 33892256 | Medrysone,2TMS,isomer #2 | CC(=O)[C@H]1CC[C@H]2[C@@H]3C[C@H](C)C4=CC(O[Si](C)(C)C)=CC[C@]4(C)[C@H]3[C@@H](O[Si](C)(C)C)C[C@]12C | 3273.5 | Standard polar | 33892256 | Medrysone,2TMS,isomer #3 | C=C(O[Si](C)(C)C)[C@H]1CC[C@H]2[C@@H]3C[C@H](C)C4=CC(=O)CC[C@]4(C)[C@H]3[C@@H](O[Si](C)(C)C)C[C@]12C | 2869.8 | Semi standard non polar | 33892256 | Medrysone,2TMS,isomer #3 | C=C(O[Si](C)(C)C)[C@H]1CC[C@H]2[C@@H]3C[C@H](C)C4=CC(=O)CC[C@]4(C)[C@H]3[C@@H](O[Si](C)(C)C)C[C@]12C | 2875.2 | Standard non polar | 33892256 | Medrysone,2TMS,isomer #3 | C=C(O[Si](C)(C)C)[C@H]1CC[C@H]2[C@@H]3C[C@H](C)C4=CC(=O)CC[C@]4(C)[C@H]3[C@@H](O[Si](C)(C)C)C[C@]12C | 3349.6 | Standard polar | 33892256 | Medrysone,2TMS,isomer #4 | CC(O[Si](C)(C)C)=C1CC[C@H]2[C@@H]3C[C@H](C)C4=CC(O[Si](C)(C)C)=CC[C@]4(C)[C@H]3[C@@H](O)C[C@]12C | 2939.9 | Semi standard non polar | 33892256 | Medrysone,2TMS,isomer #4 | CC(O[Si](C)(C)C)=C1CC[C@H]2[C@@H]3C[C@H](C)C4=CC(O[Si](C)(C)C)=CC[C@]4(C)[C@H]3[C@@H](O)C[C@]12C | 2962.2 | Standard non polar | 33892256 | Medrysone,2TMS,isomer #4 | CC(O[Si](C)(C)C)=C1CC[C@H]2[C@@H]3C[C@H](C)C4=CC(O[Si](C)(C)C)=CC[C@]4(C)[C@H]3[C@@H](O)C[C@]12C | 3279.7 | Standard polar | 33892256 | Medrysone,2TMS,isomer #5 | C=C(O[Si](C)(C)C)[C@H]1CC[C@H]2[C@@H]3C[C@H](C)C4=CC(O[Si](C)(C)C)=CC[C@]4(C)[C@H]3[C@@H](O)C[C@]12C | 2883.8 | Semi standard non polar | 33892256 | Medrysone,2TMS,isomer #5 | C=C(O[Si](C)(C)C)[C@H]1CC[C@H]2[C@@H]3C[C@H](C)C4=CC(O[Si](C)(C)C)=CC[C@]4(C)[C@H]3[C@@H](O)C[C@]12C | 2938.6 | Standard non polar | 33892256 | Medrysone,2TMS,isomer #5 | C=C(O[Si](C)(C)C)[C@H]1CC[C@H]2[C@@H]3C[C@H](C)C4=CC(O[Si](C)(C)C)=CC[C@]4(C)[C@H]3[C@@H](O)C[C@]12C | 3359.9 | Standard polar | 33892256 | Medrysone,3TMS,isomer #1 | CC(O[Si](C)(C)C)=C1CC[C@H]2[C@@H]3C[C@H](C)C4=CC(O[Si](C)(C)C)=CC[C@]4(C)[C@H]3[C@@H](O[Si](C)(C)C)C[C@]12C | 2805.0 | Semi standard non polar | 33892256 | Medrysone,3TMS,isomer #1 | CC(O[Si](C)(C)C)=C1CC[C@H]2[C@@H]3C[C@H](C)C4=CC(O[Si](C)(C)C)=CC[C@]4(C)[C@H]3[C@@H](O[Si](C)(C)C)C[C@]12C | 2938.0 | Standard non polar | 33892256 | Medrysone,3TMS,isomer #1 | CC(O[Si](C)(C)C)=C1CC[C@H]2[C@@H]3C[C@H](C)C4=CC(O[Si](C)(C)C)=CC[C@]4(C)[C@H]3[C@@H](O[Si](C)(C)C)C[C@]12C | 3239.4 | Standard polar | 33892256 | Medrysone,3TMS,isomer #2 | C=C(O[Si](C)(C)C)[C@H]1CC[C@H]2[C@@H]3C[C@H](C)C4=CC(O[Si](C)(C)C)=CC[C@]4(C)[C@H]3[C@@H](O[Si](C)(C)C)C[C@]12C | 2814.0 | Semi standard non polar | 33892256 | Medrysone,3TMS,isomer #2 | C=C(O[Si](C)(C)C)[C@H]1CC[C@H]2[C@@H]3C[C@H](C)C4=CC(O[Si](C)(C)C)=CC[C@]4(C)[C@H]3[C@@H](O[Si](C)(C)C)C[C@]12C | 2910.5 | Standard non polar | 33892256 | Medrysone,3TMS,isomer #2 | C=C(O[Si](C)(C)C)[C@H]1CC[C@H]2[C@@H]3C[C@H](C)C4=CC(O[Si](C)(C)C)=CC[C@]4(C)[C@H]3[C@@H](O[Si](C)(C)C)C[C@]12C | 3312.0 | Standard polar | 33892256 | Medrysone,1TBDMS,isomer #1 | CC(=O)[C@H]1CC[C@H]2[C@@H]3C[C@H](C)C4=CC(=O)CC[C@]4(C)[C@H]3[C@@H](O[Si](C)(C)C(C)(C)C)C[C@]12C | 3174.7 | Semi standard non polar | 33892256 | Medrysone,1TBDMS,isomer #2 | CC(O[Si](C)(C)C(C)(C)C)=C1CC[C@H]2[C@@H]3C[C@H](C)C4=CC(=O)CC[C@]4(C)[C@H]3[C@@H](O)C[C@]12C | 3284.1 | Semi standard non polar | 33892256 | Medrysone,1TBDMS,isomer #3 | CC(=O)[C@H]1CC[C@H]2[C@@H]3C[C@H](C)C4=CC(O[Si](C)(C)C(C)(C)C)=CC[C@]4(C)[C@H]3[C@@H](O)C[C@]12C | 3180.6 | Semi standard non polar | 33892256 | Medrysone,1TBDMS,isomer #4 | C=C(O[Si](C)(C)C(C)(C)C)[C@H]1CC[C@H]2[C@@H]3C[C@H](C)C4=CC(=O)CC[C@]4(C)[C@H]3[C@@H](O)C[C@]12C | 3238.6 | Semi standard non polar | 33892256 | Medrysone,2TBDMS,isomer #1 | CC(O[Si](C)(C)C(C)(C)C)=C1CC[C@H]2[C@@H]3C[C@H](C)C4=CC(=O)CC[C@]4(C)[C@H]3[C@@H](O[Si](C)(C)C(C)(C)C)C[C@]12C | 3354.2 | Semi standard non polar | 33892256 | Medrysone,2TBDMS,isomer #1 | CC(O[Si](C)(C)C(C)(C)C)=C1CC[C@H]2[C@@H]3C[C@H](C)C4=CC(=O)CC[C@]4(C)[C@H]3[C@@H](O[Si](C)(C)C(C)(C)C)C[C@]12C | 3399.9 | Standard non polar | 33892256 | Medrysone,2TBDMS,isomer #1 | CC(O[Si](C)(C)C(C)(C)C)=C1CC[C@H]2[C@@H]3C[C@H](C)C4=CC(=O)CC[C@]4(C)[C@H]3[C@@H](O[Si](C)(C)C(C)(C)C)C[C@]12C | 3504.0 | Standard polar | 33892256 | Medrysone,2TBDMS,isomer #2 | CC(=O)[C@H]1CC[C@H]2[C@@H]3C[C@H](C)C4=CC(O[Si](C)(C)C(C)(C)C)=CC[C@]4(C)[C@H]3[C@@H](O[Si](C)(C)C(C)(C)C)C[C@]12C | 3252.0 | Semi standard non polar | 33892256 | Medrysone,2TBDMS,isomer #2 | CC(=O)[C@H]1CC[C@H]2[C@@H]3C[C@H](C)C4=CC(O[Si](C)(C)C(C)(C)C)=CC[C@]4(C)[C@H]3[C@@H](O[Si](C)(C)C(C)(C)C)C[C@]12C | 3350.0 | Standard non polar | 33892256 | Medrysone,2TBDMS,isomer #2 | CC(=O)[C@H]1CC[C@H]2[C@@H]3C[C@H](C)C4=CC(O[Si](C)(C)C(C)(C)C)=CC[C@]4(C)[C@H]3[C@@H](O[Si](C)(C)C(C)(C)C)C[C@]12C | 3502.0 | Standard polar | 33892256 | Medrysone,2TBDMS,isomer #3 | C=C(O[Si](C)(C)C(C)(C)C)[C@H]1CC[C@H]2[C@@H]3C[C@H](C)C4=CC(=O)CC[C@]4(C)[C@H]3[C@@H](O[Si](C)(C)C(C)(C)C)C[C@]12C | 3304.8 | Semi standard non polar | 33892256 | Medrysone,2TBDMS,isomer #3 | C=C(O[Si](C)(C)C(C)(C)C)[C@H]1CC[C@H]2[C@@H]3C[C@H](C)C4=CC(=O)CC[C@]4(C)[C@H]3[C@@H](O[Si](C)(C)C(C)(C)C)C[C@]12C | 3363.1 | Standard non polar | 33892256 | Medrysone,2TBDMS,isomer #3 | C=C(O[Si](C)(C)C(C)(C)C)[C@H]1CC[C@H]2[C@@H]3C[C@H](C)C4=CC(=O)CC[C@]4(C)[C@H]3[C@@H](O[Si](C)(C)C(C)(C)C)C[C@]12C | 3563.6 | Standard polar | 33892256 | Medrysone,2TBDMS,isomer #4 | CC(O[Si](C)(C)C(C)(C)C)=C1CC[C@H]2[C@@H]3C[C@H](C)C4=CC(O[Si](C)(C)C(C)(C)C)=CC[C@]4(C)[C@H]3[C@@H](O)C[C@]12C | 3412.0 | Semi standard non polar | 33892256 | Medrysone,2TBDMS,isomer #4 | CC(O[Si](C)(C)C(C)(C)C)=C1CC[C@H]2[C@@H]3C[C@H](C)C4=CC(O[Si](C)(C)C(C)(C)C)=CC[C@]4(C)[C@H]3[C@@H](O)C[C@]12C | 3396.4 | Standard non polar | 33892256 | Medrysone,2TBDMS,isomer #4 | CC(O[Si](C)(C)C(C)(C)C)=C1CC[C@H]2[C@@H]3C[C@H](C)C4=CC(O[Si](C)(C)C(C)(C)C)=CC[C@]4(C)[C@H]3[C@@H](O)C[C@]12C | 3517.1 | Standard polar | 33892256 | Medrysone,2TBDMS,isomer #5 | C=C(O[Si](C)(C)C(C)(C)C)[C@H]1CC[C@H]2[C@@H]3C[C@H](C)C4=CC(O[Si](C)(C)C(C)(C)C)=CC[C@]4(C)[C@H]3[C@@H](O)C[C@]12C | 3344.8 | Semi standard non polar | 33892256 | Medrysone,2TBDMS,isomer #5 | C=C(O[Si](C)(C)C(C)(C)C)[C@H]1CC[C@H]2[C@@H]3C[C@H](C)C4=CC(O[Si](C)(C)C(C)(C)C)=CC[C@]4(C)[C@H]3[C@@H](O)C[C@]12C | 3369.5 | Standard non polar | 33892256 | Medrysone,2TBDMS,isomer #5 | C=C(O[Si](C)(C)C(C)(C)C)[C@H]1CC[C@H]2[C@@H]3C[C@H](C)C4=CC(O[Si](C)(C)C(C)(C)C)=CC[C@]4(C)[C@H]3[C@@H](O)C[C@]12C | 3573.8 | Standard polar | 33892256 | Medrysone,3TBDMS,isomer #1 | CC(O[Si](C)(C)C(C)(C)C)=C1CC[C@H]2[C@@H]3C[C@H](C)C4=CC(O[Si](C)(C)C(C)(C)C)=CC[C@]4(C)[C@H]3[C@@H](O[Si](C)(C)C(C)(C)C)C[C@]12C | 3435.9 | Semi standard non polar | 33892256 | Medrysone,3TBDMS,isomer #1 | CC(O[Si](C)(C)C(C)(C)C)=C1CC[C@H]2[C@@H]3C[C@H](C)C4=CC(O[Si](C)(C)C(C)(C)C)=CC[C@]4(C)[C@H]3[C@@H](O[Si](C)(C)C(C)(C)C)C[C@]12C | 3561.6 | Standard non polar | 33892256 | Medrysone,3TBDMS,isomer #1 | CC(O[Si](C)(C)C(C)(C)C)=C1CC[C@H]2[C@@H]3C[C@H](C)C4=CC(O[Si](C)(C)C(C)(C)C)=CC[C@]4(C)[C@H]3[C@@H](O[Si](C)(C)C(C)(C)C)C[C@]12C | 3521.8 | Standard polar | 33892256 | Medrysone,3TBDMS,isomer #2 | C=C(O[Si](C)(C)C(C)(C)C)[C@H]1CC[C@H]2[C@@H]3C[C@H](C)C4=CC(O[Si](C)(C)C(C)(C)C)=CC[C@]4(C)[C@H]3[C@@H](O[Si](C)(C)C(C)(C)C)C[C@]12C | 3427.5 | Semi standard non polar | 33892256 | Medrysone,3TBDMS,isomer #2 | C=C(O[Si](C)(C)C(C)(C)C)[C@H]1CC[C@H]2[C@@H]3C[C@H](C)C4=CC(O[Si](C)(C)C(C)(C)C)=CC[C@]4(C)[C@H]3[C@@H](O[Si](C)(C)C(C)(C)C)C[C@]12C | 3529.6 | Standard non polar | 33892256 | Medrysone,3TBDMS,isomer #2 | C=C(O[Si](C)(C)C(C)(C)C)[C@H]1CC[C@H]2[C@@H]3C[C@H](C)C4=CC(O[Si](C)(C)C(C)(C)C)=CC[C@]4(C)[C@H]3[C@@H](O[Si](C)(C)C(C)(C)C)C[C@]12C | 3560.7 | Standard polar | 33892256 |
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Spectra |
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| GC-MS SpectraSpectrum Type | Description | Splash Key | Deposition Date | Source | View |
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Predicted GC-MS | Predicted GC-MS Spectrum - Medrysone GC-MS (Non-derivatized) - 70eV, Positive | splash10-0kou-1968000000-6477c0d7e9701194dbec | 2017-09-01 | Wishart Lab | View Spectrum | Predicted GC-MS | Predicted GC-MS Spectrum - Medrysone GC-MS (1 TMS) - 70eV, Positive | splash10-0uka-3539600000-a280d5d2a7873de198e3 | 2017-10-06 | Wishart Lab | View Spectrum | Predicted GC-MS | Predicted GC-MS Spectrum - Medrysone GC-MS (Non-derivatized) - 70eV, Positive | Not Available | 2021-10-12 | Wishart Lab | View Spectrum |
MS/MS SpectraSpectrum Type | Description | Splash Key | Deposition Date | Source | View |
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Experimental LC-MS/MS | LC-MS/MS Spectrum - Medrysone LC-ESI-qTof , Positive-QTOF | splash10-0002-0329000000-a39ea3d5131dd74530f9 | 2017-09-14 | HMDB team, MONA | View Spectrum | Experimental LC-MS/MS | LC-MS/MS Spectrum - Medrysone LC-ESI-qTof , Positive-QTOF | splash10-0a4i-4901000000-b25f2b64f82210ccef6f | 2017-09-14 | HMDB team, MONA | View Spectrum | Experimental LC-MS/MS | LC-MS/MS Spectrum - Medrysone , positive-QTOF | splash10-0002-0329000000-a39ea3d5131dd74530f9 | 2017-09-14 | HMDB team, MONA | View Spectrum | Experimental LC-MS/MS | LC-MS/MS Spectrum - Medrysone , positive-QTOF | splash10-053j-3920000000-e4a574efed2d534b983c | 2017-09-14 | HMDB team, MONA | View Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - Medrysone 10V, Positive-QTOF | splash10-004j-0009000000-dbb86b9b0caf47f63423 | 2016-08-03 | Wishart Lab | View Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - Medrysone 20V, Positive-QTOF | splash10-056s-0459000000-19e6ee06a6dad18c5ac7 | 2016-08-03 | Wishart Lab | View Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - Medrysone 40V, Positive-QTOF | splash10-0pvi-4293000000-11a3580a7ecc9f1097d6 | 2016-08-03 | Wishart Lab | View Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - Medrysone 10V, Negative-QTOF | splash10-0006-0009000000-28e86ee7311b452f8e3e | 2016-08-03 | Wishart Lab | View Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - Medrysone 20V, Negative-QTOF | splash10-0006-0009000000-b446d1e7be66aa56b146 | 2016-08-03 | Wishart Lab | View Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - Medrysone 40V, Negative-QTOF | splash10-01t9-1049000000-e79e07a1ab29aca63f0f | 2016-08-03 | Wishart Lab | View Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - Medrysone 10V, Negative-QTOF | splash10-0006-0009000000-ac6607003a942882fb06 | 2021-09-22 | Wishart Lab | View Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - Medrysone 20V, Negative-QTOF | splash10-0006-0029000000-0609dc06d861d9788046 | 2021-09-22 | Wishart Lab | View Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - Medrysone 40V, Negative-QTOF | splash10-0a6s-0069000000-de9864609d2f0e26016d | 2021-09-22 | Wishart Lab | View Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - Medrysone 10V, Positive-QTOF | splash10-0002-0009000000-7b480a50024999a1446f | 2021-09-23 | Wishart Lab | View Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - Medrysone 20V, Positive-QTOF | splash10-00pj-0195000000-be5aede579feb32cbfc0 | 2021-09-23 | Wishart Lab | View Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - Medrysone 40V, Positive-QTOF | splash10-05r0-2390000000-61b8b3d1b1e80d21b69c | 2021-09-23 | Wishart Lab | View Spectrum |
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Biological Properties |
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Cellular Locations | - Cytoplasm
- Extracellular
- Membrane
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Biospecimen Locations | |
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Tissue Locations | Not Available |
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Pathways | |
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Normal Concentrations |
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Blood | Expected but not Quantified | Not Quantified | Not Available | Not Available | Taking drug identified by DrugBank entry DB00253 | | details | Urine | Expected but not Quantified | Not Quantified | Not Available | Not Available | Taking drug identified by DrugBank entry DB00253 | | details |
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Abnormal Concentrations |
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| Not Available |
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Associated Disorders and Diseases |
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Disease References | None |
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Associated OMIM IDs | None |
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External Links |
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DrugBank ID | DB00253 |
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Phenol Explorer Compound ID | Not Available |
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FooDB ID | Not Available |
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KNApSAcK ID | Not Available |
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Chemspider ID | 216968 |
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KEGG Compound ID | C14643 |
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BioCyc ID | Not Available |
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BiGG ID | Not Available |
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Wikipedia Link | Medrysone |
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METLIN ID | Not Available |
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PubChem Compound | 247839 |
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PDB ID | Not Available |
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ChEBI ID | 775124 |
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Food Biomarker Ontology | Not Available |
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VMH ID | Not Available |
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MarkerDB ID | Not Available |
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Good Scents ID | Not Available |
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References |
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Synthesis Reference | Not Available |
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Material Safety Data Sheet (MSDS) | Not Available |
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General References | - Simons K, Toomre D: Lipid rafts and signal transduction. Nat Rev Mol Cell Biol. 2000 Oct;1(1):31-9. [PubMed:11413487 ]
- Watson AD: Thematic review series: systems biology approaches to metabolic and cardiovascular disorders. Lipidomics: a global approach to lipid analysis in biological systems. J Lipid Res. 2006 Oct;47(10):2101-11. Epub 2006 Aug 10. [PubMed:16902246 ]
- Sethi JK, Vidal-Puig AJ: Thematic review series: adipocyte biology. Adipose tissue function and plasticity orchestrate nutritional adaptation. J Lipid Res. 2007 Jun;48(6):1253-62. Epub 2007 Mar 20. [PubMed:17374880 ]
- Lingwood D, Simons K: Lipid rafts as a membrane-organizing principle. Science. 2010 Jan 1;327(5961):46-50. doi: 10.1126/science.1174621. [PubMed:20044567 ]
- Gunstone, Frank D., John L. Harwood, and Albert J. Dijkstra (2007). The lipid handbook with CD-ROM. CRC Press.
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