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Record Information
Version5.0
StatusDetected but not Quantified
Creation Date2021-09-11 16:39:49 UTC
Update Date2021-09-26 23:11:52 UTC
HMDB IDHMDB0256306
Secondary Accession NumbersNone
Metabolite Identification
Common NamePerazine
DescriptionPerazine belongs to the class of organic compounds known as phenothiazines. These are polycyclic aromatic compounds containing a phenothiazine moiety, which is a linear tricyclic system that consists of a two benzene rings joined by a para-thiazine ring. Based on a literature review a small amount of articles have been published on Perazine. This compound has been identified in human blood as reported by (PMID: 31557052 ). Perazine is not a naturally occurring metabolite and is only found in those individuals exposed to this compound or its derivatives. Technically Perazine is part of the human exposome. The exposome can be defined as the collection of all the exposures of an individual in a lifetime and how those exposures relate to health. An individual's exposure begins before birth and includes insults from environmental and occupational sources.
Structure
Thumb
Synonyms
ValueSource
10-(3-(4-Methyl-1-piperazinyl)propyl)-10H-phenothiazineChEBI
N-(3-(4-Methyl-1-piperazinyl)propyl)phenothiazineChEBI
N-Methyl-piperazinyl-n'-propyl-phenothiazinChEBI
N-Methyl-piperazinylpropyl-phenothiazineChEBI
PernazineChEBI
Dihydrochloride, perazineMeSH
PerazineMeSH
Perazine dihydrochlorideMeSH
Perazine maleateMeSH
TaxilanMeSH
Maleate, perazineMeSH
Perazine maleate (1:1)MeSH
Perazine maleate (1:2)MeSH
Chemical FormulaC20H25N3S
Average Molecular Weight339.5
Monoisotopic Molecular Weight339.176918991
IUPAC Name10-[3-(4-methylpiperazin-1-yl)propyl]-10H-phenothiazine
Traditional Nameperazine
CAS Registry NumberNot Available
SMILES
CN1CCN(CCCN2C3=CC=CC=C3SC3=CC=CC=C23)CC1
InChI Identifier
InChI=1S/C20H25N3S/c1-21-13-15-22(16-14-21)11-6-12-23-17-7-2-4-9-19(17)24-20-10-5-3-8-18(20)23/h2-5,7-10H,6,11-16H2,1H3
InChI KeyWEYVCQFUGFRXOM-UHFFFAOYSA-N
Chemical Taxonomy
Description Belongs to the class of organic compounds known as phenothiazines. These are polycyclic aromatic compounds containing a phenothiazine moiety, which is a linear tricyclic system that consists of a two benzene rings joined by a para-thiazine ring.
KingdomOrganic compounds
Super ClassOrganoheterocyclic compounds
ClassBenzothiazines
Sub ClassPhenothiazines
Direct ParentPhenothiazines
Alternative Parents
Substituents
  • Phenothiazine
  • Alkyldiarylamine
  • Diarylthioether
  • Aryl thioether
  • Tertiary aliphatic/aromatic amine
  • N-alkylpiperazine
  • N-methylpiperazine
  • 1,4-diazinane
  • Piperazine
  • Para-thiazine
  • Benzenoid
  • Tertiary aliphatic amine
  • Tertiary amine
  • Azacycle
  • Thioether
  • Organic nitrogen compound
  • Organonitrogen compound
  • Hydrocarbon derivative
  • Organopnictogen compound
  • Amine
  • Aromatic heteropolycyclic compound
Molecular FrameworkAromatic heteropolycyclic compounds
External Descriptors
Ontology
Physiological effectNot Available
Disposition
ProcessNot Available
RoleNot Available
Physical Properties
StateNot Available
Experimental Molecular Properties
PropertyValueReference
Melting PointNot AvailableNot Available
Boiling PointNot AvailableNot Available
Water SolubilityNot AvailableNot Available
LogPNot AvailableNot Available
Experimental Chromatographic PropertiesNot Available
Predicted Molecular Properties
Predicted Chromatographic Properties
Spectra
Biological Properties
Cellular LocationsNot Available
Biospecimen Locations
  • Blood
Tissue LocationsNot Available
Pathways
Normal Concentrations
BiospecimenStatusValueAgeSexConditionReferenceDetails
BloodDetected but not QuantifiedNot QuantifiedNot SpecifiedNot SpecifiedNormal details
Abnormal Concentrations
Not Available
Associated Disorders and Diseases
Disease ReferencesNone
Associated OMIM IDsNone
DrugBank IDDB12710
Phenol Explorer Compound IDNot Available
FooDB IDNot Available
KNApSAcK IDC00011258
Chemspider ID4582
KEGG Compound IDC16903
BioCyc IDNot Available
BiGG IDNot Available
Wikipedia LinkPerazine
METLIN IDNot Available
PubChem CompoundNot Available
PDB IDNot Available
ChEBI ID59118
Food Biomarker OntologyNot Available
VMH IDNot Available
MarkerDB IDNot Available
Good Scents IDNot Available
References
Synthesis ReferenceNot Available
Material Safety Data Sheet (MSDS)Not Available
General References
  1. Barupal DK, Fiehn O: Generating the Blood Exposome Database Using a Comprehensive Text Mining and Database Fusion Approach. Environ Health Perspect. 2019 Sep;127(9):97008. doi: 10.1289/EHP4713. Epub 2019 Sep 26. [PubMed:31557052 ]