| HMDB0015378 | Docetaxel | 114977-28-5 |  | C43H53NO14 | 807.8792
807.346605409 | Not Available |
| HMDB0015384 | Dasatinib | 302962-49-8 |  | C22H26ClN7O2S | 488.006
487.155721508 | - van Erp NP, Gelderblom H, Guchelaar HJ: Clinical pharmacokinetics of tyrosine kinase inhibitors. Cancer Treat Rev. 2009 Dec;35(8):692-706. doi: 10.1016/j.ctrv.2009.08.004. Epub 2009 Sep 5. [PubMed:19733976 ]
- Wang L, Christopher LJ, Cui D, Li W, Iyer R, Humphreys WG, Zhang D: Identification of the human enzymes involved in the oxidative metabolism of dasatinib: an effective approach for determining metabolite formation kinetics. Drug Metab Dispos. 2008 Sep;36(9):1828-39. doi: 10.1124/dmd.107.020255. Epub 2008 Jun 12. [PubMed:18556438 ]
|
| HMDB0015388 | Lapatinib | 388082-78-8 |  | C29H26ClFN4O4S | 581.058
580.134731942 | - van Erp NP, Gelderblom H, Guchelaar HJ: Clinical pharmacokinetics of tyrosine kinase inhibitors. Cancer Treat Rev. 2009 Dec;35(8):692-706. doi: 10.1016/j.ctrv.2009.08.004. Epub 2009 Sep 5. [PubMed:19733976 ]
- Medina PJ, Goodin S: Lapatinib: a dual inhibitor of human epidermal growth factor receptor tyrosine kinases. Clin Ther. 2008 Aug;30(8):1426-47. doi: 10.1016/j.clinthera.2008.08.008. [PubMed:18803986 ]
|
| HMDB0015396 | Paliperidone | 144598-75-4 |  | C23H27FN4O3 | 426.4839
426.206718955 | - Yasui-Furukori N, Hidestrand M, Spina E, Facciola G, Scordo MG, Tybring G: Different enantioselective 9-hydroxylation of risperidone by the two human CYP2D6 and CYP3A4 enzymes. Drug Metab Dispos. 2001 Oct;29(10):1263-8. [PubMed:11560868 ]
|
| HMDB0015397 | Sunitinib | 557795-19-4 |  | C22H27FN4O2 | 398.4738
398.211804333 | Not Available |
| HMDB0015448 | Troleandomycin | 2751-09-9 |  | C41H67NO15 | 813.9684
813.451070479 | - Klees TM, Sheffels P, Dale O, Kharasch ED: Metabolism of alfentanil by cytochrome p4503a (cyp3a) enzymes. Drug Metab Dispos. 2005 Mar;33(3):303-11. Epub 2004 Nov 22. [PubMed:15557344 ]
|
| HMDB0015628 | Udenafil | 268203-93-6 |  | C25H36N6O4S | 516.656
516.25187436 | - Ku HY, Ahn HJ, Seo KA, Kim H, Oh M, Bae SK, Shin JG, Shon JH, Liu KH: The contributions of cytochromes P450 3A4 and 3A5 to the metabolism of the phosphodiesterase type 5 inhibitors sildenafil, udenafil, and vardenafil. Drug Metab Dispos. 2008 Jun;36(6):986-90. doi: 10.1124/dmd.107.020099. Epub 2008 Feb 28. [PubMed:18308836 ]
|
| HMDB0015632 | Temsirolimus | 162635-04-3 |  | C56H87NO16 | 1030.2871
1029.602485741 | Not Available |
| HMDB0015634 | Saxagliptin | 361442-04-8 |  | C18H25N3O2 | 315.41
315.194677059 | - Upreti VV, Boulton DW, Li L, Ching A, Su H, Lacreta FP, Patel CG: Effect of rifampicin on the pharmacokinetics and pharmacodynamics of saxagliptin, a dipeptidyl peptidase-4 inhibitor, in healthy subjects. Br J Clin Pharmacol. 2011 Jul;72(1):92-102. doi: 10.1111/j.1365-2125.2011.03937.x. [PubMed:21651615 ]
- Patel CG, Kornhauser D, Vachharajani N, Komoroski B, Brenner E, Handschuh del Corral M, Li L, Boulton DW: Saxagliptin, a potent, selective inhibitor of DPP-4, does not alter the pharmacokinetics of three oral antidiabetic drugs (metformin, glyburide or pioglitazone) in healthy subjects. Diabetes Obes Metab. 2011 Jul;13(7):604-14. doi: 10.1111/j.1463-1326.2011.01381.x. [PubMed:21332626 ]
- Scheen AJ: Dipeptidylpeptidase-4 inhibitors (gliptins): focus on drug-drug interactions. Clin Pharmacokinet. 2010 Sep;49(9):573-88. doi: 10.2165/11532980-000000000-00000. [PubMed:20690781 ]
|
| HMDB0015643 | Artemether | 71963-77-4 |  | C16H26O5 | 298.3746
298.178023942 | Not Available |
| HMDB0015668 | Gestodene | 60282-87-3 |  | C21H26O2 | 310.4299
310.193280076 | Not Available |
| HMDB0015672 | Cabazitaxel | 183133-96-2 |  | C45H57NO14 | 835.9324
835.377905537 | Not Available |
