Hmdb loader

HMDB0000187 (Serine) Protein Associations

Displaying all 20 metabolite protein links
HMDBP ID Name UniProt ID Gene Name Locus Type References
HMDBP00629Serine--tRNA ligase, mitochondrialQ9NP81 SARS219q13.2EnzymeNot Available
HMDBP00646Serine--tRNA ligase, cytoplasmicP49591 SARS1p13.3Enzyme
  1. Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. [PubMed:17139284 ]
  2. Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. [PubMed:17016423 ]
  3. Zhang Y, Cui J, Zhang R, Wang Y, Hong M: A novel fibrinolytic serine protease from the polychaete Nereis (Neanthes) virens (Sars): purification and characterization. Biochimie. 2007 Jan;89(1):93-103. Epub 2006 Aug 22. [PubMed:16950556 ]
  4. Follis KE, York J, Nunberg JH: Serine-scanning mutagenesis studies of the C-terminal heptad repeats in the SARS coronavirus S glycoprotein highlight the important role of the short helical region. Virology. 2005 Oct 10;341(1):122-9. [PubMed:16081124 ]
  5. McClendon CL, Vaidehi N, Kam VW, Zhang D, Goddard WA 3rd: Fidelity of seryl-tRNA synthetase to binding of natural amino acids from HierDock first principles computations. Protein Eng Des Sel. 2006 May;19(5):195-203. Epub 2006 Mar 3. [PubMed:16517553 ]
HMDBP00671L-serine dehydratase/L-threonine deaminaseP20132 SDS12q24.13Enzyme
  1. Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. [PubMed:17139284 ]
  2. Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. [PubMed:17016423 ]
  3. Velayudhan J, Jones MA, Barrow PA, Kelly DJ: L-serine catabolism via an oxygen-labile L-serine dehydratase is essential for colonization of the avian gut by Campylobacter jejuni. Infect Immun. 2004 Jan;72(1):260-8. [PubMed:14688104 ]
  4. Snell K, Walker DG: Regulation of hepatic L-serine dehydratase and L-serine-pyruvate aminotransferase in the developing neonatal rat. Biochem J. 1974 Dec;144(3):519-31. [PubMed:4377655 ]
  5. Wong HC, Lessie TG: Hydroxy amino acid metabolism in Pseudomonas cepacia: role of L-serine deaminase in dissimilation of serine, glycine, and threonine. J Bacteriol. 1979 Oct;140(1):240-5. [PubMed:500557 ]
HMDBP00779Cystathionine beta-synthaseP35520 CBS21q22.3Unknown
  1. Sen S, Banerjee R: A pathogenic linked mutation in the catalytic core of human cystathionine beta-synthase disrupts allosteric regulation and allows kinetic characterization of a full-length dimer. Biochemistry. 2007 Apr 3;46(13):4110-6. Epub 2007 Mar 13. [PubMed:17352495 ]
  2. Qu K, Lee SW, Bian JS, Low CM, Wong PT: Hydrogen sulfide: neurochemistry and neurobiology. Neurochem Int. 2008 Jan;52(1-2):155-65. Epub 2007 Jun 8. [PubMed:17629356 ]
HMDBP00789Serine--pyruvate aminotransferaseP21549 AGXT2q37.3Unknown
  1. Yard BA, Carter LG, Johnson KA, Overton IM, Dorward M, Liu H, McMahon SA, Oke M, Puech D, Barton GJ, Naismith JH, Campopiano DJ: The structure of serine palmitoyltransferase; gateway to sphingolipid biosynthesis. J Mol Biol. 2007 Jul 27;370(5):870-86. Epub 2007 May 10. [PubMed:17559874 ]
  2. Ikushiro H, Islam MM, Tojo H, Hayashi H: Molecular characterization of membrane-associated soluble serine palmitoyltransferases from Sphingobacterium multivorum and Bdellovibrio stolpii. J Bacteriol. 2007 Aug;189(15):5749-61. Epub 2007 Jun 8. [PubMed:17557831 ]
  3. Cowart LA, Hannun YA: Selective substrate supply in the regulation of yeast de novo sphingolipid synthesis. J Biol Chem. 2007 Apr 20;282(16):12330-40. Epub 2007 Feb 23. [PubMed:17322298 ]
  4. Son JH, Yoo HH, Kim DH: Activation of de novo synthetic pathway of ceramides is responsible for the initiation of hydrogen peroxide-induced apoptosis in HL-60 cells. J Toxicol Environ Health A. 2007 Aug;70(15-16):1310-8. [PubMed:17654249 ]
HMDBP00792Serine hydroxymethyltransferase, mitochondrialP34897 SHMT212q12-q14EnzymeNot Available
HMDBP00794Serine hydroxymethyltransferase, cytosolicP34896 SHMT117p11.2EnzymeNot Available
HMDBP00886Serine palmitoyltransferase 1O15269 SPTLC19q22.2Enzyme
  1. Yard BA, Carter LG, Johnson KA, Overton IM, Dorward M, Liu H, McMahon SA, Oke M, Puech D, Barton GJ, Naismith JH, Campopiano DJ: The structure of serine palmitoyltransferase; gateway to sphingolipid biosynthesis. J Mol Biol. 2007 Jul 27;370(5):870-86. Epub 2007 May 10. [PubMed:17559874 ]
HMDBP00887Phosphoserine phosphataseP78330 PSPH7p11.2UnknownNot Available
HMDBP00888Serine palmitoyltransferase 2O15270 SPTLC214q24.3Enzyme
  1. Yard BA, Carter LG, Johnson KA, Overton IM, Dorward M, Liu H, McMahon SA, Oke M, Puech D, Barton GJ, Naismith JH, Campopiano DJ: The structure of serine palmitoyltransferase; gateway to sphingolipid biosynthesis. J Mol Biol. 2007 Jul 27;370(5):870-86. Epub 2007 May 10. [PubMed:17559874 ]
HMDBP02190Phosphatidylserine synthase 1P48651 PTDSS18q22EnzymeNot Available
HMDBP02960Phosphatidylserine synthase 2Q9BVG9 PTDSS211p15.5EnzymeNot Available
HMDBP03110Neutral amino acid transporter AP43007 SLC1A42p15-p13UnknownNot Available
HMDBP05340Monocarboxylate transporter 10Q8TF71 SLC16A106q21-q22Transporter
  1. Kim DK, Kanai Y, Chairoungdua A, Matsuo H, Cha SH, Endou H: Expression cloning of a Na+-independent aromatic amino acid transporter with structural similarity to H+/monocarboxylate transporters. J Biol Chem. 2001 May 18;276(20):17221-8. Epub 2001 Feb 20. [PubMed:11278508 ]
HMDBP08972Serine dehydratase-likeQ96GA7 SDSL12q24.13EnzymeNot Available
HMDBP08974Serine palmitoyltransferase 3Q9NUV7 SPTLC320p12.1EnzymeNot Available
HMDBP08975Serine racemaseQ9GZT4 SRR17p13Enzyme
  1. Fujitani Y, Horiuchi T, Ito K, Sugimoto M: Serine racemases from barley, Hordeum vulgare L., and other plant species represent a distinct eukaryotic group: gene cloning and recombinant protein characterization. Phytochemistry. 2007 Jun;68(11):1530-6. Epub 2007 May 17. [PubMed:17499824 ]
  2. Ying-Luan Z, Zhao YL, Mori H: [Role of D-serine in the mammalian brain]. Brain Nerve. 2007 Jul;59(7):725-30. [PubMed:17663143 ]
HMDBP08981Serine hydroxymethyltransferaseA8MYA6 SHMT117p11.2EnzymeNot Available
HMDBP08988Serine hydroxymethyltransferaseQ5BJF5 SHMT212q12-q14EnzymeNot Available
HMDBP10743Serine incorporator 1Q9NRX5 SERINC16q22.31UnknownNot Available
Displaying all 20 metabolite protein links