Showing metabocard for FAD (HMDB0001248)

General function:

Involved in oxidoreductase activity

Specific function:

Lipoamide dehydrogenase is a component of the glycine cleavage system as well as of the alpha-ketoacid dehydrogenase complexes. Involved in the hyperactivation of spermatazoa during capacitation and in the spermatazoal acrosome reaction.

Gene Name:

DLD

Uniprot ID:

P09622

Molecular weight:

54176.91

General function:

Involved in acyl-CoA dehydrogenase activity

Specific function:

Not Available

Gene Name:

ACADL

Uniprot ID:

P28330

Molecular weight:

47655.275

Reactions

General function:

Involved in acyl-CoA dehydrogenase activity

Specific function:

Not Available

Gene Name:

ACADS

Uniprot ID:

P16219

Molecular weight:

44296.705

Reactions

General function:

Involved in acyl-CoA dehydrogenase activity

Specific function:

This enzyme is specific for acyl chain lengths of 4 to 16.

Gene Name:

ACADM

Uniprot ID:

P11310

Molecular weight:

46587.98

Reactions

General function:

Involved in oxidation reduction

Specific function:

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).

Gene Name:

MT-ND1

Uniprot ID:

P03886

Molecular weight:

35660.055

General function:

Involved in NADH dehydrogenase activity

Specific function:

Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone

Gene Name:

NDUFB1

Uniprot ID:

O75438

Molecular weight:

6961.2

General function:

Involved in catalytic activity

Specific function:

Involved primarily in ATP hydrolysis at the plasma membrane. Plays a role in regulating pyrophosphate levels, and functions in bone mineralization and soft tissue calcification. In vitro, has a broad specificity, hydrolyzing other nucleoside 5' triphosphates such as GTP, CTP, TTP and UTP to their corresponding monophosphates with release of pyrophosphate and diadenosine polyphosphates, and also 3',5'-cAMP to AMP. May also be involved in the regulation of the availability of nucleotide sugars in the endoplasmic reticulum and Golgi, and the regulation of purinergic signaling. Appears to modulate insulin sensitivity.

Gene Name:

ENPP1

Uniprot ID:

P22413

Molecular weight:

104923.58

Reactions

General function:

Involved in oxidoreductase activity, acting on NADH or NADPH

Specific function:

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).

Gene Name:

NDUFS2

Uniprot ID:

O75306

Molecular weight:

51851.59

General function:

Involved in succinate dehydrogenase activity

Specific function:

Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).

Gene Name:

SDHC

Uniprot ID:

Q99643

Molecular weight:

16650.185

General function:

Involved in oxidoreductase activity

Specific function:

Metabolizes sarcosine, L-pipecolic acid and L-proline.

Gene Name:

PIPOX

Uniprot ID:

Q9P0Z9

Molecular weight:

44065.515