Human Metabolome Database: Showing metabocard for Calcium (HMDB0000464)

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enzymes (1083)transporters (2) Show 1085 proteins

Record Information

Version

5.0

Status

Detected and Quantified

Creation Date

2006-08-15 17:25:35 UTC

Update Date

2022-03-07 02:49:02 UTC

HMDB ID

HMDB0000464

Secondary Accession Numbers

HMDB00464

Metabolite Identification

Common Name

Calcium

Description

Calcium is essential for the normal growth and maintenance of bones and teeth, and calcium requirements must be met throughout life. Requirements are greatest during periods of growth, such as childhood, during pregnancy and when breast-feeding. Long-term calcium deficiency can lead to osteoporosis, in which the bone deteriorates and there is an increased risk of fractures. Adults need between 1,000 and 1,300 mg of calcium in their daily diet. Calcium is essential for living organisms, particularly in cell physiology, and is the most common metal in many animals. Physiologically, it exists as an ion in the body. Calcium combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes. Calcium is an important component of a healthy diet. A deficit can affect bone and tooth formation, while overretention can cause kidney stones. Vitamin D is needed to absorb calcium. Dairy products, such as milk and cheese, are a well-known source of calcium. However, some individuals are allergic to dairy products and even more people, particularly those of non-European descent, are lactose-intolerant, leaving them unable to consume dairy products. Fortunately, many other good sources of calcium exist. These include: seaweeds such as kelp, wakame and hijiki; nuts and seeds (like almonds and sesame); beans; amaranth; collard greens; okra; rutabaga; broccoli; kale; and fortified products such as orange juice and soy milk. Calcium has also been found to assist in the production of lymphatic fluids. Furthermore, calcium is found to be associated with primary hypomagnesemia, which is an inborn error of metabolism.

Structure

MOL 3D MOL SDF 3D SDF PDB 3D PDB SMILES InChI

View in JSmol View Stereo Labels

Synonyms

Value	Source
Ca(2+)	ChEBI
Ca2+	ChEBI
CALCIUM ion	ChEBI
Calcium, doubly charged positive ion	ChEBI
Calcium(2+)	Kegg
Ca	HMDB
Calcium element	HMDB

Chemical Formula

Average Molecular Weight

40.078

Monoisotopic Molecular Weight

39.962591155

IUPAC Name

calcium(2+) ion

Traditional Name

calcium(2+) ion

CAS Registry Number

7440-70-2

SMILES

[Ca++]

InChI Identifier

InChI=1S/Ca/q+2

InChI Key

BHPQYMZQTOCNFJ-UHFFFAOYSA-N

Chemical Taxonomy

Description

Belongs to the class of inorganic compounds known as homogeneous alkaline earth metal compounds. These are inorganic compounds containing only metal atoms,with the largest atom being a alkaline earth metal atom.

Kingdom

Inorganic compounds

Super Class

Homogeneous metal compounds

Class

Homogeneous alkaline earth metal compounds

Sub Class

Not Available

Direct Parent

Homogeneous alkaline earth metal compounds

Alternative Parents

Not Available