Hmdb loader

HMDBP00469 (Tryptophan 5-hydroxylase 1) Metabolite Associations

Displaying all 9 metabolite protein links
HMDB ID Name CAS NumberStructureFormula Average Mass
Monoisotopic Mass 		References
HMDB0000027Tetrahydrobiopterin62989-33-7ThumbC9H15N5O3241.2471
241.117489371
  1. Sumi-Ichinose C, Urano F, Kuroda R, Ohye T, Kojima M, Tazawa M, Shiraishi H, Hagino Y, Nagatsu T, Nomura T, Ichinose H: Catecholamines and serotonin are differently regulated by tetrahydrobiopterin. A study from 6-pyruvoyltetrahydropterin synthase knockout mice. J Biol Chem. 2001 Nov 2;276(44):41150-60. Epub 2001 Aug 21. [PubMed:11517215 ]
HMDB0000038Dihydrobiopterin6779-87-9ThumbC9H13N5O3239.2312
239.101839307
  1. Wang L, Erlandsen H, Haavik J, Knappskog PM, Stevens RC: Three-dimensional structure of human tryptophan hydroxylase and its implications for the biosynthesis of the neurotransmitters serotonin and melatonin. Biochemistry. 2002 Oct 22;41(42):12569-74. [PubMed:12379098 ]
HMDB00004725-Hydroxy-L-tryptophan4350-09-8ThumbC11H12N2O3220.2246
220.08479226		Not Available
HMDB0000692Fe2+15438-31-0ThumbFe55.845
55.934942133		Not Available
HMDB0000929L-Tryptophan73-22-3ThumbC11H12N2O2204.2252
204.089877638
  1. Pavon JA, Fitzpatrick PF: Insights into the catalytic mechanisms of phenylalanine and tryptophan hydroxylase from kinetic isotope effects on aromatic hydroxylation. Biochemistry. 2006 Sep 12;45(36):11030-7. [PubMed:16953590 ]
  2. Langfort J, Baranczuk E, Pawlak D, Chalimoniuk M, Lukacova N, Marsala J, Gorski J: The effect of endurance training on regional serotonin metabolism in the brain during early stage of detraining period in the female rat. Cell Mol Neurobiol. 2006 Oct-Nov;26(7-8):1327-42. Epub 2006 Aug 1. [PubMed:16897368 ]
  3. Nakamura K, Hasegawa H: Developmental role of tryptophan hydroxylase in the nervous system. Mol Neurobiol. 2007 Feb;35(1):45-54. [PubMed:17519505 ]
  4. Invernizzi RW: Role of TPH-2 in brain function: news from behavioral and pharmacologic studies. J Neurosci Res. 2007 Nov 1;85(14):3030-5. [PubMed:17492791 ]
  5. Neckameyer WS, Coleman CM, Eadie S, Goodwin SF: Compartmentalization of neuronal and peripheral serotonin synthesis in Drosophila melanogaster. Genes Brain Behav. 2007 Nov;6(8):756-69. Epub 2007 Mar 21. [PubMed:17376153 ]
HMDB0001377Oxygen7782-44-7ThumbO231.9988
31.989829244		Not Available
HMDB0002111Water7732-18-5ThumbH2O18.0153
18.010564686		Not Available
HMDB00022154a-Carbinolamine tetrahydrobiopterin79647-29-3ThumbC9H13N5O3239.2312
239.101839307		Not Available
HMDB00022814a-Hydroxytetrahydrobiopterin1379003-93-6ThumbC9H15N5O4257.25
257.112403983		Not Available
Displaying all 9 metabolite protein links