HMDB0015349 | Halofantrine | 69756-53-2 | ![Thumb](/structures/HMDB0015349/thumb.svg) | C26H30Cl2F3NO | 500.424 499.165654616 | - Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. doi: 10.1093/nar/gkp970. Epub 2009 Nov 24. [PubMed:19934256 ]
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HMDB0005036 | Fluticasone propionate | 80474-14-2 | ![Thumb](/structures/HMDB0005036/thumb.svg) | C25H31F3O5S | 500.571 500.184429407 | - Pearce RE, Leeder JS, Kearns GL: Biotransformation of fluticasone: in vitro characterization. Drug Metab Dispos. 2006 Jun;34(6):1035-40. Epub 2006 Mar 24. [PubMed:16565171 ]
- Murai T, Reilly CA, Ward RM, Yost GS: The inhaled glucocorticoid fluticasone propionate efficiently inactivates cytochrome P450 3A5, a predominant lung P450 enzyme. Chem Res Toxicol. 2010 Aug 16;23(8):1356-64. doi: 10.1021/tx100124k. [PubMed:20707410 ]
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HMDB0014839 | Amprenavir | 161814-49-9 | ![Thumb](/structures/HMDB0014839/thumb.svg) | C25H35N3O6S | 505.627 505.224656557 | - Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. doi: 10.1093/nar/gkp970. Epub 2009 Nov 24. [PubMed:19934256 ]
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HMDB0014423 | Argatroban | 74863-84-6 | ![Thumb](/structures/HMDB0014423/thumb.svg) | C23H36N6O5S | 508.634 508.246788982 | - Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. doi: 10.1093/nar/gkp970. Epub 2009 Nov 24. [PubMed:19934256 ]
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HMDB0015628 | Udenafil | 268203-93-6 | ![Thumb](/structures/HMDB0015628/thumb.svg) | C25H36N6O4S | 516.656 516.25187436 | - Ku HY, Ahn HJ, Seo KA, Kim H, Oh M, Bae SK, Shin JG, Shon JH, Liu KH: The contributions of cytochromes P450 3A4 and 3A5 to the metabolism of the phosphodiesterase type 5 inhibitors sildenafil, udenafil, and vardenafil. Drug Metab Dispos. 2008 Jun;36(6):986-90. doi: 10.1124/dmd.107.020099. Epub 2008 Feb 28. [PubMed:18308836 ]
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HMDB0014538 | Beclometasone dipropionate | 5534-09-8 | ![Thumb](/structures/HMDB0014538/thumb.svg) | C28H37ClO7 | 521.042 520.222781245 | - Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. doi: 10.1093/nar/gkp970. Epub 2009 Nov 24. [PubMed:19934256 ]
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HMDB0014832 | Daunorubicin | 20830-81-3 | ![Thumb](/structures/HMDB0014832/thumb.svg) | C27H29NO10 | 527.5199 527.179146153 | - Wang T, Chen FY, Han JY, Shao NX, Ou-Yuang RR: [Study of CYP3A5 in drug resistance mechanisms in acute leukemia]. Zhonghua Xue Ye Xue Za Zhi. 2003 Jun;24(6):286-9. [PubMed:12859862 ]
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HMDB0015258 | Dutasteride | 164656-23-9 | ![Thumb](/structures/HMDB0015258/thumb.svg) | C27H30F6N2O2 | 528.5297 528.221147444 | - Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. doi: 10.1093/nar/gkp970. Epub 2009 Nov 24. [PubMed:19934256 ]
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HMDB0012242 | Ketoconazole | 65277-42-1 | ![Thumb](/structures/HMDB0012242/thumb.svg) | C26H28Cl2N4O4 | 531.431 530.148760818 | Not Available |
HMDB0014811 | Aprepitant | 170729-80-3 | ![Thumb](/structures/HMDB0014811/thumb.svg) | C23H21F7N4O3 | 534.4267 534.150187993 | Not Available |
HMDB0014365 | Nelfinavir | 159989-64-7 | ![Thumb](/structures/HMDB0014365/thumb.svg) | C32H45N3O4S | 567.782 567.313077633 | - Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. doi: 10.1093/nar/gkp970. Epub 2009 Nov 24. [PubMed:19934256 ]
- Zhou SF, Zhou ZW, Yang LP, Cai JP: Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675. Epub 2009 Sep 1. [PubMed:19515014 ]
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HMDB0015388 | Lapatinib | 388082-78-8 | ![Thumb](/structures/HMDB0015388/thumb.svg) | C29H26ClFN4O4S | 581.058 580.134731942 | - van Erp NP, Gelderblom H, Guchelaar HJ: Clinical pharmacokinetics of tyrosine kinase inhibitors. Cancer Treat Rev. 2009 Dec;35(8):692-706. doi: 10.1016/j.ctrv.2009.08.004. Epub 2009 Sep 5. [PubMed:19733976 ]
- Medina PJ, Goodin S: Lapatinib: a dual inhibitor of human epidermal growth factor receptor tyrosine kinases. Clin Ther. 2008 Aug;30(8):1426-47. doi: 10.1016/j.clinthera.2008.08.008. [PubMed:18803986 ]
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HMDB0014900 | Irinotecan | 100286-90-6 | ![Thumb](/structures/HMDB0014900/thumb.svg) | C33H38N4O6 | 586.678 586.279134968 | - Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. doi: 10.1093/nar/gkp970. Epub 2009 Nov 24. [PubMed:19934256 ]
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HMDB0014911 | Etoposide | 33419-42-0 | ![Thumb](/structures/HMDB0014911/thumb.svg) | C29H32O13 | 588.5566 588.18429111 | - Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. doi: 10.1093/nar/gkp970. Epub 2009 Nov 24. [PubMed:19934256 ]
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HMDB0014351 | Reserpine | 50-55-5 | ![Thumb](/structures/HMDB0014351/thumb.svg) | C33H40N2O9 | 608.6787 608.273380888 | - Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. doi: 10.1093/nar/gkp970. Epub 2009 Nov 24. [PubMed:19934256 ]
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HMDB0014669 | Lercanidipine | 100427-26-7 | ![Thumb](/structures/HMDB0014669/thumb.svg) | C36H41N3O6 | 611.7272 611.299536059 | Not Available |
HMDB0014369 | Indinavir | 150378-17-9 | ![Thumb](/structures/HMDB0014369/thumb.svg) | C36H47N5O4 | 613.7895 613.362805017 | - Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. doi: 10.1093/nar/gkp970. Epub 2009 Nov 24. [PubMed:19934256 ]
- Zhou SF, Zhou ZW, Yang LP, Cai JP: Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675. Epub 2009 Sep 1. [PubMed:19515014 ]
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HMDB0003178 | Heme | 14875-96-8 | ![Thumb](/structures/HMDB0003178/thumb.svg) | C34H32FeN4O4 | 616.487 616.177297665 | Not Available |
HMDB0014587 | Teniposide | 29767-20-2 | ![Thumb](/structures/HMDB0014587/thumb.svg) | C32H32O13S | 656.654 656.1563618 | - Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. doi: 10.1093/nar/gkp970. Epub 2009 Nov 24. [PubMed:19934256 ]
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HMDB0015362 | Saquinavir | 127779-20-8 | ![Thumb](/structures/HMDB0015362/thumb.svg) | C38H50N6O5 | 670.8408 670.38426874 | - Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. doi: 10.1093/nar/gkp970. Epub 2009 Nov 24. [PubMed:19934256 ]
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HMDB0015298 | Itraconazole | 84625-61-6 | ![Thumb](/structures/HMDB0015298/thumb.svg) | C35H38Cl2N8O4 | 705.633 704.239307158 | Not Available |
HMDB0014646 | Ritonavir | 155213-67-5 | ![Thumb](/structures/HMDB0014646/thumb.svg) | C37H48N6O5S2 | 720.944 720.312760056 | - Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. doi: 10.1093/nar/gkp970. Epub 2009 Nov 24. [PubMed:19934256 ]
- Zhou SF, Zhou ZW, Yang LP, Cai JP: Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675. Epub 2009 Sep 1. [PubMed:19515014 ]
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HMDB0014344 | Erythromycin | 114-07-8 | ![Thumb](/structures/HMDB0014344/thumb.svg) | C37H67NO13 | 733.9268 733.461241235 | Not Available |
HMDB0000217 | NADP | 53-59-8 | ![Thumb](/structures/HMDB0000217/thumb.svg) | C21H28N7O17P3 | 743.405 743.075452041 | Not Available |
HMDB0000221 | NADPH | 53-57-6 | ![Thumb](/structures/HMDB0000221/thumb.svg) | C21H30N7O17P3 | 745.4209 745.091102105 | Not Available |