Search Results for metabolites
Searching metabolites for histamine returned 108 results.
HMDB0000870
51-45-6
Blood Cerebrospinal Fluid (CSF) Feces Saliva Urine
2-(1H-imidazol-4-yl)ethan-1-amine
Matched synonyms: … Histamine …
Matched name: … Histamine …
Matched description: … Histamine is an amine derived by enzymatic decarboxylation of histidine. ... High amounts of histamine have been found in spinach, oats and ryes. ... Histamine belongs to the class of organic compounds known as 2-arylethylamines. …
Matched name: … Histamine …
Matched description: … Histamine is an amine derived by enzymatic decarboxylation of histidine. ... High amounts of histamine have been found in spinach, oats and ryes. ... Histamine belongs to the class of organic compounds known as 2-arylethylamines. …
HMDB0015557
86-21-5
Blood Urine
dimethyl[3-phenyl-3-(pyridin-2-yl)propyl]amine
Matched description: … [PubChem]Antihistamines such as pheniramine appear to compete with histamine for histamine H1- receptor ... It is one of the histamine H1 antagonists with little sedative action. ... They effectively exert competitive antagonism of histamine for H1-receptors. …
HMDB0001861
644-42-8
Blood Urine
2-(1-methyl-1H-imidazol-5-yl)ethan-1-amine
Matched synonyms: … L-Histamine deriv. 1 …
Matched description: … N tau-methylhistamine is one of the histamine metabolites. ... N tau-methylhistamine in plasma and urine is a good parameter for histamine release, and the determination ... , a very short half-life time or bacterial production) than determinations of histamine itself (PMID …
Matched description: … N tau-methylhistamine is one of the histamine metabolites. ... N tau-methylhistamine in plasma and urine is a good parameter for histamine release, and the determination ... , a very short half-life time or bacterial production) than determinations of histamine itself (PMID …
HMDB0015692
482-15-5
Blood Urine
dimethyl(1-{9-thia-2,4-diazatricyclo[8.4.0.0³,⁸]tetradeca-1(14),3(8),4,6,10,12-hexaen-2-yl}propan-2-yl)amine
Matched description: … symptoms brought on by histamine. ... H1 antagonist and binds to the histamine H1 receptor. ... It is an antihistamine and anticholinergic used as an antipruritic.Isothipendyl is a selective histamine …
HMDB0014571
486-12-4
Blood Urine
2-[(1E)-1-(4-methylphenyl)-3-(pyrrolidin-1-yl)prop-1-en-1-yl]pyridine
Matched description: … symptoms brought on by histamine. ... [PubChem]Triprolidine binds to the histamine H1 receptor. ... It is the first generation histamine H1 antagonist used in allergic rhinitis; asthma; and urticaria. …
(2S,4E)-4-[(2Z)-2-{[2-(1H-imidazol-5-yl)ethyl]imino}ethylidene]-1,2,3,4-tetrahydropyridine-2,6-dicarboxylic acid
Matched name: … Histamine-betaxanthin …
HMDB0002820
2625-49-2
Blood Cerebrospinal Fluid (CSF) Feces Saliva Urine
2-(1-methyl-1H-imidazol-4-yl)acetic acid
Matched description: … Methylimidazoleacetic acid is the main metabolite of histamine. ... marker of any changes in histamine metabolism in the body. ... A possible explanation is that basal histamine turnover is related to body size. …
HMDB0014857
3964-81-6
Blood Urine
2-(1-methylpiperidin-4-ylidene)-4-azatricyclo[9.4.0.0³,⁸]pentadeca-1(15),3(8),4,6,11,13-hexaene
Matched description: … Antihistamines such as azatadine appear to compete with histamine for histamine H1- receptor sites on ... The antihistamines antagonize those pharmacological effects of histamine which are mediated through activation ... receptor sites and thereby reduce the intensity of allergic reactions and tissue injury response involving histamine …
HMDB0015691
5636-83-9
Blood Urine
dimethyl(2-{3-[1-(pyridin-2-yl)ethyl]-1H-inden-2-yl}ethyl)amine
Matched description: … symptoms brought on by histamine. ... H1 antagonist and binds to the histamine H1 receptor. ... antihistamine/anticholinergic used orally and locally as an antipruritic.Dimethindene is a selective histamine …
HMDB0015238
79516-68-0
Blood Urine
(3S,4R)-1-[4-cyano-4-(4-fluorophenyl)cyclohexyl]-3-methyl-4-phenylpiperidine-4-carboxylic acid
Matched description: … Levocabastine does not block histamine release but, rather, prevents histamine binding and activity. ... It works by competing with histamine for H1-receptor sites on effector cells. ... It thereby prevents, but does not reverse, responses mediated by histamine alone. …
HMDB0014930
91-81-6
Blood Urine
N-benzyl-N-[2-(dimethylamino)ethyl]pyridin-2-amine
Matched description: … symptoms brought on by histamine. ... [PubChem]Tripelennamine binds to the histamine H1 receptor. ... It is a histamine H1 antagonist with low sedative action but frequent gastrointestinal irritation. …
HMDB0014549
132-21-8
Blood Urine
[(3S)-3-(4-bromophenyl)-3-(pyridin-2-yl)propyl]dimethylamine
Matched description: … symptoms brought on by histamine. ... Dexbrompheniramine competitively binds to the histamine H1-receptor. ... This blocks the action of endogenous histamine, which subsequently leads to temporary relief of the negative …
HMDB0015216
87233-61-2
Blood Urine
1-(2-ethoxyethyl)-2-(4-methyl-1,4-diazepan-1-yl)-1H-1,3-benzodiazole
Matched description: … for the H1 histamine receptor. ... [Wikipedia]Emedastine is a relatively selective, histamine H1 antagonist. ... In vitro examinations of emedastine's affinity for histamine receptors demonstrate relative selectivity …
HMDB0015277
147-20-6
Blood Urine
4-(diphenylmethoxy)-1-methylpiperidine
Matched description: … Antihistamines prevent, but do not reverse, responses mediated by histamine alone. ... Antihistamines used in the treatment of allergy act by competing with histamine for H 1-receptor sites ... Antihistamines antagonize, in varying degrees, most of the pharmacological effects of histamine, including …
HMDB0014644
51481-61-9
Blood Urine
(Z)-N-cyano-N''-methyl-N'-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl)guanidine
Matched description: … A histamine congener, it competitively inhibits histamine binding to histamine H2 receptors. …
HMDB0014578
129-03-3
Blood Urine
1-methyl-4-{tricyclo[9.4.0.0³,⁸]pentadeca-1(15),3,5,7,9,11,13-heptaen-2-ylidene}piperidine
Matched description: … brought on by histamine HA-receptor binding. ... [PubChem]Cyproheptadine competes with free histamine for binding at HA-receptor sites. ... It is a serotonin antagonist and a histamine H1 blocker used as antipruritic, appetite stimulant, antiallergic …
HMDB0015038
1982-37-2
Blood Urine
10-[(1-methylpyrrolidin-3-yl)methyl]-10H-phenothiazine
Matched description: … symptoms brought on by histamine. ... It is used in the treatment of various dermatoses to relieve pruritus.Methdilazine binds to the histamine ... This blocks the action of endogenous histamine, which subsequently leads to temporary relief of the negative …
HMDB0014417
105-20-4
Blood Feces Urine
2-(1H-pyrazol-3-yl)ethan-1-amine
Matched description: … [PubChem]Betazole is a histamine analogue. ... It is a histamine H2 agonist used clinically to test gastric secretory function. ... It produces the same effects as histamine, binding the H2 receptor which is a mediator of gastric acid …
HMDB0014428
15686-51-8
Blood Urine
(2R)-2-{2-[(1R)-1-(4-chlorophenyl)-1-phenylethoxy]ethyl}-1-methylpyrrolidine
Matched description: … [PubChem]Clemastine is a selective histamine H1 antagonist and binds to the histamine H1 receptor. ... symptoms brought on by histamine. ... It is an ethanolamine-derivative, first generation histamine H1 antagonist used in hay fever, rhinitis …
HMDB0015689
91-75-8
Blood Urine
N-benzyl-N-(4,5-dihydro-1H-imidazol-2-ylmethyl)aniline
Matched description: … symptoms brought on by histamine. ... This blocks the action of endogenous histamine, which subsequently leads to temporary relief of the negative ... combination with naphazoline, to relieve the symptoms of allergic conjunctivitis.Antazoline binds to the histamine …
HMDB0015367
1808-12-4
Blood Urine
{2-[(4-bromophenyl)(phenyl)methoxy]ethyl}dimethylamine
Matched description: … brought on by histamine HA-receptor binding. ... This antagonizes the effects of histamine on HA-receptors, leading to a reduction of the negative symptoms ... Ethanolamine antihistamines produce marked sedation in most patientsBromodiphenhydramine competes with free histamine …
HMDB0015556
82-88-2
Blood Urine
2-methyl-9-phenyl-1H,2H,3H,4H,9H-indeno[2,1-c]pyridine
Matched description: … Antihistamines such as phenindamine appear to compete with histamine for histamine H1- receptor sites ... Phenindamine blocks the effects of the naturally occurring chemical histamine in your body. ... The antihistamines antagonize those pharmacological effects of histamine which are mediated through activation …
HMDB0014906
113806-05-6
Blood Urine
2-[(2Z)-2-[3-(dimethylamino)propylidene]-9-oxatricyclo[9.4.0.0³,⁸]pentadeca-1(15),3(8),4,6,11,13-hexaen-5-yl]acetic acid
Matched description: … Used to treat allergic conjunctivitis (itching eyes), olopatadine inhibits the release of histamine from ... It is a relatively selective histamine H1 antagonist that inhibits the in vivo and in vitro type 1 immediate ... hypersensitivity reaction including inhibition of histamine induced effects on human conjunctival epithelial …
HMDB0004181
19639-03-3
2-(1-methyl-1H-imidazol-4-yl)acetaldehyde
Matched description: … Methyimidazole acetaldehyde is a metabolite of histamine. ... and acetaldehyde can successfully compete with methylimidazole acetaldehyde, since the alcohol and histamine …
HMDB0015376
84-96-8
Blood Urine
dimethyl[2-methyl-3-(10H-phenothiazin-10-yl)propyl]amine
Matched description: … brought on by histamine HA-receptor binding. ... [PubChem]Trimeprazine competes with free histamine for binding at HA-receptor sites. ... This antagonizes the effects of histamine on HA-receptors, leading to a reduction of the negative symptoms …