HMDB0001248 | FAD | 146-14-5 | | C27H33N9O15P2 | 785.5497 785.157134455 | Not Available |
HMDB0001487 | NADH | 58-68-4 | | C21H29N7O14P2 | 665.441 665.124771695 | Not Available |
HMDB0000902 | NAD | 53-84-9 | | C21H27N7O14P2 | 663.4251 663.109121631 | Not Available |
HMDB0014884 | Deferoxamine | 70-51-9 | | C25H48N6O8 | 560.684 560.353362542 | - Rinaldo JE, Gorry M: Protection by deferoxamine from endothelial injury: a possible link with inhibition of intracellular xanthine oxidase. Am J Respir Cell Mol Biol. 1990 Dec;3(6):525-33. [PubMed:2252579 ]
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HMDB0014832 | Daunorubicin | 20830-81-3 | | C27H29NO10 | 527.5199 527.179146153 | - Yee SB, Pritsos CA: Comparison of oxygen radical generation from the reductive activation of doxorubicin, streptonigrin, and menadione by xanthine oxidase and xanthine dehydrogenase. Arch Biochem Biophys. 1997 Nov 15;347(2):235-41. [PubMed:9367530 ]
- Yee SB, Pritsos CA: Reductive activation of doxorubicin by xanthine dehydrogenase from EMT6 mouse mammary carcinoma tumors. Chem Biol Interact. 1997 May 2;104(2-3):87-101. [PubMed:9212777 ]
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HMDB0013946 | 8-Hydroxycarvedilol | | | C24H26N2O5 | 422.4736 422.184171952 | - Yue TL, McKenna PJ, Gu JL, Cheng HY, Ruffolo RE Jr, Feuerstein GZ: Carvedilol, a new vasodilating beta adrenoceptor blocker antihypertensive drug, protects endothelial cells from damage initiated by xanthine-xanthine oxidase and neutrophils. Cardiovasc Res. 1994 Mar;28(3):400-6. [PubMed:7909721 ]
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HMDB0014969 | Trifluoperazine | 117-89-5 | | C21H24F3N3S | 407.496 407.164303088 | - Hirata Y, Ishii K, Taguchi T, Suita S, Takeshige K: Conversion of xanthine dehydrogenase to xanthine oxidase during ischemia of the rat small intestine and the effect of trifluoperazine on the conversion. J Pediatr Surg. 1993 Apr;28(4):597-600. [PubMed:8483075 ]
- Greene EL, Paller MS: Calcium and free radicals in hypoxia/reoxygenation injury of renal epithelial cells. Am J Physiol. 1994 Jan;266(1 Pt 2):F13-20. [PubMed:8304479 ]
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HMDB0015093 | Carboplatin | 41575-94-4 | | C6H12N2O4Pt | 371.254 371.044481331 | - Husai K, Jagannathan R, Hasan Z, Trammell GL, Rybak LP, Hazelrigg SR, Somani SM: Dose response of carboplatin-induced nephrotoxicity in rats. Pharmacol Toxicol. 2002 Aug;91(2):83-9. [PubMed:12420797 ]
- Husain K, Whitworth C, Rybak LP: Time response of carboplatin-induced nephrotoxicity in rats. Pharmacol Res. 2004 Sep;50(3):291-300. [PubMed:15225673 ]
- Husain K, Whitworth C, Somani SM, Rybak LP: Carboplatin-induced oxidative stress in rat cochlea. Hear Res. 2001 Sep;159(1-2):14-22. [PubMed:11520631 ]
- Husain K, Whitworth C, Hazelrigg S, Rybak L: Carboplatin-induced oxidative injury in rat inferior colliculus. Int J Toxicol. 2003 Sep-Oct;22(5):335-42. [PubMed:14555405 ]
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HMDB0015408 | Bismuth Subsalicylate | 14882-18-9 | | C7H5BiO4 | 362.0926 361.999166889 | - Lewis RW, Olivier G: In vitro oxidation of 6-MP and its metallo complexes by xanthine oxidase. Res Commun Chem Pathol Pharmacol. 1977 Oct;18(2):377-80. [PubMed:918354 ]
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HMDB0014656 | Cisplatin | 15663-27-1 | | Cl2H4N2Pt | 298.035 296.939928001 | - Erdogan S, Tosyali E, Duzguner V, Kucukgul A, Aslantas O, Celik S: Cisplatin reduces Brucella melitensis-infected cell number by inducing apoptosis, oxidant and pro-inflammatory cytokine production. Res Vet Sci. 2010 Apr;88(2):218-26. doi: 10.1016/j.rvsc.2009.09.002. Epub 2009 Oct 8. [PubMed:19818462 ]
- Yilmaz HR, Sogut S, Ozyurt B, Ozugurlu F, Sahin S, Isik B, Uz E, Ozyurt H: The activities of liver adenosine deaminase, xanthine oxidase, catalase, superoxide dismutase enzymes and the levels of malondialdehyde and nitric oxide after cisplatin toxicity in rats: protective effect of caffeic acid phenethyl ester. Toxicol Ind Health. 2005 May;21(3-4):67-73. [PubMed:15986578 ]
- Cetin R, Devrim E, Kilicoglu B, Avci A, Candir O, Durak I: Cisplatin impairs antioxidant system and causes oxidation in rat kidney tissues: possible protective roles of natural antioxidant foods. J Appl Toxicol. 2006 Jan-Feb;26(1):42-6. [PubMed:16158393 ]
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HMDB0015128 | Azathioprine | 446-86-6 | | C9H7N7O2S | 277.263 277.038193193 | - Dubinsky MC: Azathioprine, 6-mercaptopurine in inflammatory bowel disease: pharmacology, efficacy, and safety. Clin Gastroenterol Hepatol. 2004 Sep;2(9):731-43. [PubMed:15354273 ]
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HMDB0000195 | Inosine | 58-63-9 | | C10H12N4O5 | 268.2261 268.080769514 | - STIRPE F, DELLACORTE E: REGULATION OF XANTHINE DEHYDROGENASE IN CHICK LIVER. EFFECT OF STARVATION AND OF ADMINISTRATION OF PURINES AND PURINE NUCLEOSIDES. Biochem J. 1965 Feb;94:309-13. [PubMed:14348191 ]
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HMDB0015299 | Procarbazine | 671-16-9 | | C12H19N3O | 221.2988 221.152812245 | Not Available |
HMDB0014994 | Chlorphenesin | 104-29-0 | | C9H11ClO3 | 202.635 202.039671925 | - Springer RH, Dimmitt MK, Novinson T, O'Brien DE, Robins RK, Simon LN, Miller JP: Synthesis and enzymic activity of some novel xanthine oxidase inhibitors. 3-Substituted 5,7-dihydroxypyrazolo(1,5-alpha)pyrimidines. J Med Chem. 1976 Feb;19(2):291-6. [PubMed:2778 ]
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HMDB0001256 | Spermine | 71-44-3 | | C10H26N4 | 202.3402 202.215746852 | - Lovaas E, Carlin G: Spermine: an anti-oxidant and anti-inflammatory agent. Free Radic Biol Med. 1991;11(5):455-61. [PubMed:1663062 ]
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HMDB0014480 | Nitrofurazone | 59-87-0 | | C6H6N4O4 | 198.1362 198.0389047 | - Tatsumi K, Kitamura S, Yoshimura H: Reduction of nitrofuran derivatives by xanthine oxidase and microsomes. Isolation and identification of reduction products. Arch Biochem Biophys. 1976 Jul;175(1):131-7. [PubMed:952514 ]
- Kutcher WW, McCalla DR: Aerobic reduction of 5-nitro-2-furaldehyde semicarbazone by rat liver xanthine dehydrogenase. Biochem Pharmacol. 1984 Mar 1;33(5):799-805. [PubMed:6585203 ]
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HMDB0011103 | 1,7-Dimethyluric acid | 33868-03-0 | | C7H8N4O3 | 196.1634 196.059640142 | Not Available |
HMDB0001982 | 3,7-Dimethyluric acid | 13087-49-5 | | C7H8N4O3 | 196.1634 196.059640142 | Not Available |
HMDB0060417 | 6-Thiourate | | | C5H4N4O2S | 184.176 184.005496082 | Not Available |
HMDB0003099 | 1-Methyluric acid | 708-79-2 | | C6H6N4O3 | 182.1368 182.043990078 | Not Available |
HMDB0011107 | 7-Methyluric acid | | | C6H6N4O3 | 182.1368 182.043990078 | Not Available |
HMDB0001860 | Paraxanthine | 611-59-6 | | C7H8N4O2 | 180.164 180.06472552 | Not Available |
HMDB0002825 | Theobromine | 83-67-0 | | C7H8N4O2 | 180.164 180.06472552 | Not Available |
HMDB0001892 | Menadione | 58-27-5 | | C11H8O2 | 172.18 172.0524295 | - Yee SB, Pritsos CA: Comparison of oxygen radical generation from the reductive activation of doxorubicin, streptonigrin, and menadione by xanthine oxidase and xanthine dehydrogenase. Arch Biochem Biophys. 1997 Nov 15;347(2):235-41. [PubMed:9367530 ]
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HMDB0000289 | Uric acid | 69-93-2 | | C5H4N4O3 | 168.1103 168.028340014 | Not Available |