HMDB0003948 | (2E)-Decenoyl-CoA | 10018-95-8 | | C31H52N7O17P3S | 919.768 919.235323499 | Not Available |
HMDB0003712 | (2E)-Dodecenoyl-CoA | 1066-12-2 | | C33H56N7O17P3S | 947.82 947.266625539 | Not Available |
HMDB0003945 | (2E)-Hexadecenoyl-CoA | 4460-95-1 | | C37H64N7O17P3S | 1003.93 1003.329225797 | Not Available |
HMDB0003949 | (2E)-Octenoyl-CoA | 10018-94-7 | | C29H48N7O17P3S | 891.714 891.204023371 | Not Available |
HMDB0003946 | (2E)-Tetradecenoyl-CoA | 38795-33-4 | | C35H60N7O17P3S | 975.874 975.297923755 | Not Available |
HMDB0001041 | 2-Methylbutyryl-CoA | 87069-91-8 | | C26H44N7O17P3S | 851.651 851.172723243 | Not Available |
HMDB0011660 | 2-Methylhexanoyl-CoA | | | C28H48N7O17P3S | 879.704 879.204023371 | Not Available |
HMDB0004257 | 3Z-dodecenoyl-CoA | 2152-91-2 | | C33H56N7O17P3S | 947.821 947.266623627 | Not Available |
HMDB0001206 | Acetyl-CoA | 72-89-9 | | C23H38N7O17P3S | 809.571 809.125773051 | Not Available |
HMDB0002307 | Acrylyl-CoA | 5776-58-9 | | C24H38N7O17P3S | 821.58 821.12577496 | Not Available |
HMDB0005006 | Atorvastatin | 134523-00-5 | | C33H35FN2O5 | 558.6398 558.253000445 | Not Available |
HMDB0015465 | Bezafibrate | 41859-67-0 | | C19H20ClNO4 | 361.819 361.10808584 | - Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. [PubMed:11752352 ]
- Pedraza N, Solanes G, Carmona MC, Iglesias R, Vinas O, Mampel T, Vazquez M, Giralt M, Villarroya F: Impaired expression of the uncoupling protein-3 gene in skeletal muscle during lactation: fibrates and troglitazone reverse lactation-induced downregulation of the uncoupling protein-3 gene. Diabetes. 2000 Jul;49(7):1224-30. [PubMed:10909982 ]
- Cabrero A, Alegret M, Sanchez R, Adzet T, Laguna JC, Vazquez M: Peroxisome proliferator-activated receptor alpha (PPARalpha) activators, bezafibrate and Wy-14,643, increase uncoupling protein-3 mRNA levels without modifying the mitochondrial membrane potential in primary culture of rat preadipocytes. Arch Biochem Biophys. 2000 Aug 15;380(2):353-9. [PubMed:10933891 ]
- Inoue I, Goto S, Matsunaga T, Nakajima T, Awata T, Hokari S, Komoda T, Katayama S: The ligands/activators for peroxisome proliferator-activated receptor alpha (PPARalpha) and PPARgamma increase Cu2+,Zn2+-superoxide dismutase and decrease p22phox message expressions in primary endothelial cells. Metabolism. 2001 Jan;50(1):3-11. [PubMed:11172467 ]
- Guan Y, Breyer MD: Peroxisome proliferator-activated receptors (PPARs): novel therapeutic targets in renal disease. Kidney Int. 2001 Jul;60(1):14-30. [PubMed:11422732 ]
- Bonilla S, Redonnet A, Noel-Suberville C, Groubet R, Pallet V, Higueret P: Effect of a pharmacological activation of PPAR on the expression of RAR and TR in rat liver. J Physiol Biochem. 2001 Mar;57(1):1-8. [PubMed:11519881 ]
- Goldenberg I, Benderly M, Goldbourt U: Update on the use of fibrates: focus on bezafibrate. Vasc Health Risk Manag. 2008;4(1):131-41. [PubMed:18629356 ]
- Fruchart JC, Duriez P: Mode of action of fibrates in the regulation of triglyceride and HDL-cholesterol metabolism. Drugs Today (Barc). 2006 Jan;42(1):39-64. [PubMed:16511610 ]
|
HMDB0001088 | Butyryl-CoA | 2140-48-9 | | C25H42N7O17P3S | 837.624 837.157073179 | Not Available |
HMDB0014774 | Clofibrate | 637-07-0 | | C12H15ClO3 | 242.699 242.070972053 | - Barclay TB, Peters JM, Sewer MB, Ferrari L, Gonzalez FJ, Morgan ET: Modulation of cytochrome P-450 gene expression in endotoxemic mice is tissue specific and peroxisome proliferator-activated receptor-alpha dependent. J Pharmacol Exp Ther. 1999 Sep;290(3):1250-7. [PubMed:10454501 ]
- Murata M, Kaji H, Takahashi Y, Iida K, Mizuno I, Okimura Y, Abe H, Chihara K: Stimulation by eicosapentaenoic acids of leptin mRNA expression and its secretion in mouse 3T3-L1 adipocytes in vitro. Biochem Biophys Res Commun. 2000 Apr 13;270(2):343-8. [PubMed:10753628 ]
- Hunt MC, Lindquist PJ, Peters JM, Gonzalez FJ, Diczfalusy U, Alexson SE: Involvement of the peroxisome proliferator-activated receptor alpha in regulating long-chain acyl-CoA thioesterases. J Lipid Res. 2000 May;41(5):814-23. [PubMed:10787442 ]
- Casas F, Domenjoud L, Rochard P, Hatier R, Rodier A, Daury L, Bianchi A, Kremarik-Bouillaud P, Becuwe P, Keller J, Schohn H, Wrutniak-Cabello C, Cabello G, Dauca M: A 45 kDa protein related to PPARgamma2, induced by peroxisome proliferators, is located in the mitochondrial matrix. FEBS Lett. 2000 Jul 28;478(1-2):4-8. [PubMed:10922459 ]
- Komuves LG, Hanley K, Lefebvre AM, Man MQ, Ng DC, Bikle DD, Williams ML, Elias PM, Auwerx J, Feingold KR: Stimulation of PPARalpha promotes epidermal keratinocyte differentiation in vivo. J Invest Dermatol. 2000 Sep;115(3):353-60. [PubMed:10951268 ]
- Gelosa P, Banfi C, Gianella A, Brioschi M, Pignieri A, Nobili E, Castiglioni L, Cimino M, Tremoli E, Sironi L: Peroxisome proliferator-activated receptor {alpha} agonism prevents renal damage and the oxidative stress and inflammatory processes affecting the brains of stroke-prone rats. J Pharmacol Exp Ther. 2010 Nov;335(2):324-31. doi: 10.1124/jpet.110.171090. Epub 2010 Jul 29. [PubMed:20671072 ]
- Palkar PS, Anderson CR, Ferry CH, Gonzalez FJ, Peters JM: Effect of prenatal peroxisome proliferator-activated receptor alpha (PPARalpha) agonism on postnatal development. Toxicology. 2010 Sep 30;276(1):79-84. doi: 10.1016/j.tox.2010.07.008. Epub 2010 Jul 15. [PubMed:20637823 ]
|
HMDB0002009 | Crotonoyl-CoA | 38795-21-0 | | C25H40N7O17P3S | 835.608 835.141423115 | Not Available |
HMDB0006404 | Decanoyl-CoA (n-C10:0CoA) | 1264-57-9 | | C31H54N7O17P3S | 921.783 921.250973563 | Not Available |
HMDB0004258 | Eicosanoyl-CoA | 15895-27-9 | | C41H74N7O17P3S | 1062.06 1061.407476119 | Not Available |
HMDB0015173 | Fenofibrate | 49562-28-9 | | C20H21ClO4 | 360.831 360.112836867 | - Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. [PubMed:11752352 ]
- Clavey V, Copin C, Mariotte MC, Bauge E, Chinetti G, Fruchart J, Fruchart JC, Dallongeville J, Staels B: Cell culture conditions determine apolipoprotein CIII secretion and regulation by fibrates in human hepatoma HepG2 cells. Cell Physiol Biochem. 1999;9(3):139-49. [PubMed:10494028 ]
- Chaput E, Saladin R, Silvestre M, Edgar AD: Fenofibrate and rosiglitazone lower serum triglycerides with opposing effects on body weight. Biochem Biophys Res Commun. 2000 May 10;271(2):445-50. [PubMed:10799317 ]
- Casas F, Pineau T, Rochard P, Rodier A, Daury L, Dauca M, Cabello G, Wrutniak-Cabello C: New molecular aspects of regulation of mitochondrial activity by fenofibrate and fasting. FEBS Lett. 2000 Sep 29;482(1-2):71-4. [PubMed:11018525 ]
- Bouly M, Masson D, Gross B, Jiang XC, Fievet C, Castro G, Tall AR, Fruchart JC, Staels B, Lagrost L, Luc G: Induction of the phospholipid transfer protein gene accounts for the high density lipoprotein enlargement in mice treated with fenofibrate. J Biol Chem. 2001 Jul 13;276(28):25841-7. Epub 2001 May 7. [PubMed:11342537 ]
- Dana SL, Hoener PA, Bilakovics JM, Crombie DL, Ogilvie KM, Kauffman RF, Mukherjee R, Paterniti JR Jr: Peroxisome proliferator-activated receptor subtype-specific regulation of hepatic and peripheral gene expression in the Zucker diabetic fatty rat. Metabolism. 2001 Aug;50(8):963-71. [PubMed:11474486 ]
- Guerre-Millo M, Gervois P, Raspe E, Madsen L, Poulain P, Derudas B, Herbert JM, Winegar DA, Willson TM, Fruchart JC, Berge RK, Staels B: Peroxisome proliferator-activated receptor alpha activators improve insulin sensitivity and reduce adiposity. J Biol Chem. 2000 Jun 2;275(22):16638-42. [PubMed:10828060 ]
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HMDB0015371 | Gemfibrozil | 25812-30-0 | | C15H22O3 | 250.3334 250.15689457 | - Clavey V, Copin C, Mariotte MC, Bauge E, Chinetti G, Fruchart J, Fruchart JC, Dallongeville J, Staels B: Cell culture conditions determine apolipoprotein CIII secretion and regulation by fibrates in human hepatoma HepG2 cells. Cell Physiol Biochem. 1999;9(3):139-49. [PubMed:10494028 ]
- Bosse Y, Pascot A, Dumont M, Brochu M, Prud'homme D, Bergeron J, Despres JP, Vohl MC: Influences of the PPAR alpha-L162V polymorphism on plasma HDL(2)-cholesterol response of abdominally obese men treated with gemfibrozil. Genet Med. 2002 Jul-Aug;4(4):311-5. [PubMed:12172398 ]
- Pahan K, Jana M, Liu X, Taylor BS, Wood C, Fischer SM: Gemfibrozil, a lipid-lowering drug, inhibits the induction of nitric-oxide synthase in human astrocytes. J Biol Chem. 2002 Nov 29;277(48):45984-91. Epub 2002 Sep 18. [PubMed:12244038 ]
- Shoji Y, Sanekata A, Sato M, Imaizumi K: Preparation of antiserum against rat delta6-desaturase and its use to evaluate the desaturase protein levels in rats treated with gemfibrozil, a ligand for peroxisome proliferator-activated receptor alpha. Biosci Biotechnol Biochem. 2003 May;67(5):1177-8. [PubMed:12834305 ]
- Rizvi F, Iftikhar M, George JP: Beneficial effects of fish liver preparations of sea bass (Lates calcarifer) versus gemfibrozil in high fat diet-induced lipid-intolerant rats. J Med Food. 2003 Summer;6(2):123-8. [PubMed:12935323 ]
|
HMDB0001290 | Glutaconyl-CoA | 167357-83-7 | | C26H40N7O19P3S | 879.62 879.131254264 | Not Available |
HMDB0006497 | Heptadecanoyl CoA | 3546-17-6 | | C38H68N7O17P3S | 1019.97 1019.360524011 | Not Available |
HMDB0012969 | Heptanoyl-CoA | | | C28H48N7O17P3S | 879.704 879.204023371 | Not Available |
HMDB0002845 | Hexanoyl-CoA | 5060-32-2 | | C27H46N7O17P3S | 865.677 865.188373307 | Not Available |
HMDB0001243 | Isobutyryl-CoA | 15621-60-0 | | C25H42N7O17P3S | 837.624 837.157073179 | Not Available |
HMDB0001113 | Isovaleryl-CoA | 6244-91-3 | | C26H44N7O17P3S | 851.651 851.172723243 | Not Available |